The incidence of dementia and obstructive sleep apnea (OSA) increases with age. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Full text may need a subscription
Research
27,380 Alzheimer's and dementia studies in plain English, each scored out of 100.
Hearing loss has been linked to many types of cognitive decline in adults, including an association between hearing loss severity and dementia. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Effective communication by nursing home staff is related to a higher quality of life and a decrease in verbal and physical aggression and depression in nursing home residents. 2 key findings →
Participants: 24 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
The aim of this study was to assess chewing ability using color-changeable chewing gum and to show the association between chewing ability and geriatric functions, as well as dietary status in the community-dwelling elderly. 4 key findings →
Evidence: low
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Performance on cognitive tests can be affected by age, education, and also selection bias. 4 key findings →
Evidence: moderate
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The existing evidence suggests that both could be addressed with either antecedent behavior management strategies, such as creating verbal scripts and routines (e.g., an “escape” routine when he is losing his temper, greeting routines for customers), or consequence-oriented management such as reinforcement of either positive behaviors or low rates of negative behaviors (Ylvisaker, Turkstra, & Coelho, 2005). 4 key findings →
Design: systematic review Evidence: high
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Typical normative models appear appropriate for remote self‐administered measures and are sensitive to cognitive impairment. 3 key findings →
Participants: 167 Evidence: low
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Dementia and depression are two prevalent disorders that warrant significant attention due to their high prevalence and substantial contribution to the global burden of disease. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
42/100
Gender has an impact on CR, but not through socio‐economic variables. 2 key findings →
Participants: 440 Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
Regular opioid use was associated with a 20% higher risk of all-cause dementia and a 49% higher risk of vascular dementia (VD) compared with those not using analgesics. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
42/100
Our findings revealed a significant impact of unfavorable medical and psychiatric histories on processing speed and visual episodic memory decline (Hazard Ratio (HR) = 1.34, 95% CI: 1.20–1.51, p = 6.06 × 10⁻7; HR = 1.50, 95% CI: 1.22–1.86, p = 1.62 × 10⁻4, respectively). 4 key findings →
Participants: 453,950 Evidence: low
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The MI group significantly improved in attention-executive functioning (p = 0.003) compared to ACI (Cohen's d: 0.47, 95% CI 0.13-0.79). 5 key findings →
Evidence: low
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After adjusting for baseline scores via ANCOVA, the experimental group demonstrated significantly higher post-intervention outcomes compared to the control group (p < 0.001). 5 key findings →
Participants: 58 Evidence: low
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Although a substantial proportion of TG participants achieved high MI accuracy values, statistical analyses revealed no cognitive improvements specific to TG, suggesting limited efficacy of the MI-based protocol compared to classical cognitive stimulation. 5 key findings →
Evidence: high
Full summary, score breakdown and related studies → Original source Free full text
42/100
This study included 5899 older adults (65+) of whom 687 reported dysphagia (median age, 80 years; 62.2% female). 5 key findings →
Participants: 5,899 Evidence: low
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Research in animals and humans has shown that mastication maintains cognitive function in the hippocampus, a brain area important for learning and memory. 2 key findings →
Evidence: low
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41/100
Cognitive impairment has been reported in middle aged patients with end stage heart failure. 4 key findings →
Evidence: low
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This narrative review examines how socioeconomic disparities accelerate health decline in older adults. 1 key finding →
Design: narrative review Evidence: low
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41/100
In adjusted analyses, walkability was not related to cognitive impairment in the full sample (OR = 0.89 (95% CI: 0.61‐1.28 for highest vs lowest quartile). 2 key findings →
Participants: 1,625 Evidence: low
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Overall, these findings highlight the generally robust, protective effect of social support on cognitive abilities in this large, diverse cohort of older adults. 5 key findings →
Participants: 2,811 Evidence: moderate
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Lower objective SES was associated with poorer performance on all cognitive domains: episodic memory (β = 0.115, p = 0.003), executive function (β = 0.210, p 0.05). 5 key findings →
Design: cross-sectional Evidence: high
Full summary, score breakdown and related studies → Original source Free full text
Loneliness moderated the relationship between national ADI scores and short-term visuospatial memory. 5 key findings →
Design: cross-sectional Participants: 136 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Obesity and its associated metabolic disturbances increase the risk of cognitive decline, dementia, and anxiety-related disorders. 2 key findings →
Evidence: low
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The project is expected to generate evidence on the effectiveness, feasibility, and cost-effectiveness of multidomain interventions implemented across diverse real-world settings, including community, hospital, and long-term care. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Change in QoL (decreased, maintained or improved) was determined using a cross-tabulation test. 4 key findings →
Evidence: high
Full summary, score breakdown and related studies → Original source Free full text
From across this tag
10 of the 1,130 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
- Strategies to prevent falls and fractures in hospitals and care homes and effect of cognitive impairment: systematic review and meta-analyses
- The neurobiology of brain and cognitive reserve: mental and physical activity as modulators of brain disorders
- Changing the food environment: the effect of trained volunteers on mealtime care for older people in hospital
- Efficacy of Multidomain Intervention Against Physio-cognitive Decline Syndrome: A Cluster-randomized Trial
- Association of Daily Driving Behaviors With Mild Cognitive Impairment in Older Adults Followed Over 10 Years
- Long sleep duration, cognitive performance, and the moderating role of depression: A cross‐sectional analysis in the Framingham Heart Study
- The Mediterranean Diet and Cognitive Function among Healthy Older Adults in a 6-Month Randomised Controlled Trial: The MedLey Study
- Association Between Lifestyle at Different Life Periods and Brain Integrity in Older Adults
- ASSOCIATION BETWEEN VIOLENT CRIME INCIDENT PROXIMITY AND COGNITIVE FUNCTION IN OLDER AFRICAN AMERICANS
- Longitudinal Trajectories of the Cognitive Function Index in the A4 Study
Where “Free full text” comes from
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
How the 0–100 score works — and why some entries are capped
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
- Journal tier up to 10 pts
- Journal's citation record up to 4 pts
- Study design up to 12 pts
- Strength of evidence up to 5 pts
- Peer-review validation up to 10 pts
- How recent up to 5 pts
- Sample size up to 4 pts
- Effect reported up to 3 pts
- Studied in people up to 3 pts
- Randomised / blinded up to 2 pts
- Times cited up to 7 pts
- Citations per year up to 5 pts
- Impact for its field and year up to 6 pts
- Cited by studies here up to 6 pts
- Still being cited up to 4 pts
- Senior author's track record up to 4 pts
- Institution's track record up to 3 pts
- Multi-centre collaboration up to 3 pts
- Indexed in PubMed up to 2 pts
- Free to read up to 2 pts
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 27,380 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
What this library is — and isn't
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,380 records, built mostly from automated pulls of Europe PMC (60.6% of the library) and OpenAlex (18.6%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,032 records (3.8% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →