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Home › Research › Topic

Air pollution and environmental exposures

294 studies in this group. A computer grouped them by what their titles and summaries are about, not by a hand-made list. The name describes most of the group, not every study in it.

Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.

Highest usefulness score first. Studies without a score come last.

  1. Neurotoxicity of Diesel Exhaust Particles

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Journal of Alzheimer's disease : JAD 2022 Risk factors

    DEP exposure at 100μg/m3 for 5 h, but not lower doses, caused oxidative damage, complement and microglia activation in cerebral cortex and corpus callosum.

  2. TUBE Project: Transport-Derived Ultrafines and the Brain Effects

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. International journal of environmental research and public health 2021-12-28 Risk factors

    The adverse effects of air pollutants on the respiratory and cardiovascular systems are unquestionable.

  3. Air Pollution Particulate Matter Amplifies White Matter Vascular Pathology and Demyelination Caused by Hypoperfusion

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Frontiers in immunology 2021-11-16 Risk factors

    Cerebrovascular pathologies are commonly associated with dementia.

  4. Outdoor green space exposure and brain health measures related to Alzheimer's disease: a rapid review

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. BMJ open 2021-05-03 Risk factors

    PubMed, Embase and Web of Science Core Collection were searched for articles meeting the criteria published on/before 13 February 2020.

  5. Urban Air Pollution Nanoparticles from Los Angeles: Recently Decreased Neurotoxicity

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Journal of Alzheimer's disease : JAD 2021 Risk factors

    Five older nPM batches (2009-2017) and four recent nPM batches (2018, 2019) for NF-κB and Nrf2 induction showed declines in nPM potency after 2017 that paralleled declines of in vivo activity from independent exposures in different years.

  6. Particulate Matter Exposure Exacerbates Amyloid-β Plaque Deposition and Gliosis in APP/PS1 Mice

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Journal of Alzheimer's disease : JAD 2021 Risk factors

    The Aβ plaque load was significantly increased in the hippocampus of PM2.5-exposed APP/PS1 mice compared to their respective FA controls.

  7. Human Health and Ocean Pollution

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Annals of global health 2020-12-03 Risk factors

    Bans on persistent organic pollutants (POPs) have reduced pollution by PCBs and DDT.

  8. Cadmium and Lead Exposure, Nephrotoxicity, and Mortality

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Toxics 2020-10-13 Risk factors

    The present review aims to provide an update on health risks associated with the low-to-moderate levels of environmental cadmium (Cd) and lead (Pb) to which most populations are exposed.

  9. Neurological disorders vis-à-vis climate change

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Early human development 2020-10-01 Risk factors

    Climate change is one of the biggest challenges humanity is facing in the 21st century.

  10. Neuropathological Mechanisms Associated with Pesticides in Alzheimer’s Disease

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Toxics 2020-03-25 Risk factors

    Environmental toxicants have been implicated in neurodegenerative diseases, and pesticide exposure is a suspected environmental risk factor for Alzheimer's disease (AD).

  11. Evolutionarily conserved susceptibility of the mitochondrial respiratory chain to SDHI pesticides and its consequence on the impact of SDHIs on human cultured cells

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. PLoS ONE 2019-11-07 Risk factors

    Succinate dehydrogenase (SDH) inhibitors (SDHIs) are used worldwide to limit the proliferation of molds on plants and plant products.

  12. Traffic-Related Air Pollution, APOE ε4 Status, and Neurodevelopmental Outcomes among School Children Enrolled in the BREATHE Project (Catalonia, Spain)

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Environmental Health Perspectives 2018-08-01 Risk factors

    APOE ε4 allele carriers had significantly higher behavior problem scores than noncarriers, and adverse associations with PAHs and NO2 were stronger or limited to ε4 carriers for behavior problem scores (P-interaction 0.03 and 0.04), caudate volume (P-interaction 0.04 and 0.03), and inattentiveness trajectories (P-interaction 0.15 and 0.08, respectively).

  13. The emerging risk of exposure to air pollution on cognitive decline and Alzheimer's disease - Evidence from epidemiological and animal studies

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Biomedical journal 2018-06-01 Risk factors

    As incidence of Alzheimer's disease (AD) and other neurodegenerative diseases rise, there is increasing interest in environmental factors which may contribute to disease onset and progression.

  14. PM2.5 exposure aggravates oligomeric amyloid beta-induced neuronal injury and promotes NLRP3 inflammasome activation in an in vitro model of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Journal of neuroinflammation 2018-05-02 Risk factors

    For the first time, these results suggested that the effects of PM2.5 under AD context were possibly mediated by NLRP3 inflammasome activation, which was triggered by ROS.

  15. Hallmarks of Alzheimer disease are evolving relentlessly in Metropolitan Mexico City infants, children and young adults. APOE4 carriers have higher suicide risk and higher odds of reaching NFT stage V at ≤ 40 years of age

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Environmental research 2018-03-26 Risk factors

    Exposures to fine particulate matter (PM 2.5 ) and ozone (O 3 ) above USEPA standards are associated with Alzheimer's disease (AD) risk.

  16. Diesel engine exhaust accelerates plaque formation in a mouse model of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Particle and fibre toxicology 2017-08-30 Risk factors

    Inhalation exposure to DEE causes accelerated plaque formation and motor function impairment in 5XFAD transgenic mice.

  17. Toll-like receptor 4 in glial inflammatory responses to air pollution in vitro and in vivo

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Journal of neuroinflammation 2017-04-14 Risk factors

    These results show TLR4 activation is integral in brain inflammatory responses to air pollution, and warrant further study of TLR4 in accelerated cognitive aging by air pollution.

  18. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Lancet (London, England) 2012-12-01 Risk factors

    Ischaemic heart disease and stroke collectively killed 12·9 million people in 2010, or one in four deaths worldwide, compared with one in five in 1990; 1·3 million deaths were due to diabetes, twice as many as in 1990.

  19. Potential occupational risks for neurodegenerative diseases

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. American journal of industrial medicine 2005-07-01 Risk factors

    Support was observed for hypothesized excess neurodegenerative disease associated with a variety of occupations, 60 Hz magnetic fields and welding.

  20. Essential metals in health and disease

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Chemico-biological interactions 2022-09-22 Risk factors

    In total, twenty elements appear to be essential for the correct functioning of the human body, half of which are metals and half are non-metals.

  21. Air Pollution, Ultrafine Particles, and Your Brain: Are Combustion Nanoparticle Emissions and Engineered Nanoparticles Causing Preventable Fatal Neurodegenerative Diseases and Common Neuropsychiatric Outcomes?

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Environmental science & technology 2022-02-22 Risk factors

    Exposure to particulate matter (PM) pollution damages the human brain.

  22. Air Pollution and the Risk of Parkinson's Disease: A Review

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Movement disorders : official journal of the Movement Disorder Society 2022-01-19 Risk factors

    Parkinson's disease, as well as other neurodegenerative disorders, are primarily characterized by pathological accumulation of proteins, inflammation, and neuron loss.

  23. PM2.5 exposure in association with AD-related neuropathology and cognitive outcomes

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Environmental pollution (Barking, Essex : 1987) 2021-10-08 Risk factors

    Particulate matter with a diameter of less than 2.5 μm or PM2.5 is recognized worldwide as a cause of public health problems, mainly associated with respiratory and cardiovascular diseases.

  24. Biodegradable polymers and their nano-composites for the removal of endocrine-disrupting chemicals (EDCs) from wastewater: A review

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Environmental research 2021-07-15 Risk factors

    Endocrine-disrupting chemicals (EDCs) target the endocrine system by interfering with the natural hormones in the body leading to adverse effects on human and animal health.

  25. Reduced repressive epigenetic marks, increased DNA damage and Alzheimer's disease hallmarks in the brain of humans and mice exposed to particulate urban air pollution

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Environmental research 2020-02-04 Risk factors

    Exposure to air pollutants is associated with an increased risk of developing Alzheimer's disease (AD).

From across this topic

7 of the 294 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 7. The same 7 appear here every time.

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