Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.
Highest usefulness score first. Studies without a score come last.
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A reduction in the incidence of smoking will likely reduce the future prevalence of AD.
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To examine the relationship between smoking and Alzheimer's disease (AD) after controlling for study design, quality, secular trend, and tobacco industry affiliation of the authors, electronic databases were searched; 43 individual studies met the inclusion criteria.
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Both environmental exposures and genetics are known to play important roles in shaping human aging.
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Higher chronic exposure to SO2 was associated with a faster decline in memory score, whereas chronic exposure to CO, NO2 , and PM10 were not associated with the rate of cognitive decline.
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Long-term exposure to PM 2.5 contributed to the development of cognitive decline, which may be partly explained by brain amyloid accumulation indicative of increased AD risk.
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Increased exposure to urban green space was associated with reduced incidence of dementia and stroke.
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Air pollution exposure may exacerbate AD development.
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Evidence is emerging that greater exposure to airborne pollutants is associated with increased risk of dementia.
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Current evidence for an association between ambient ozone exposure and mental health outcomes is inconclusive and further high quality studies are needed to assess any potential links given the strong biologic plausibility.
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PM2.5 exposure may contribute to WM loss in older women.
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Neurodegenerative disease in patients with chronic obstructive pulmonary disease (COPD) was observed.
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Cognitive impairment associated with aging is a serious and growing public health problem.
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Strong conclusions remain elusive, although the weight of the evidence suggests an adverse association between PM2.5 and cognitive decline.
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The PSI was higher in Kaohsiung and compared with Pingtung patients, Kaohsiung patients were exposed to higher average annual concentrations of CO, NO2, PM10, and SO2.
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Between Jan 1, 2000, and Dec 31, 2016, of 63 038 019 individuals who were aged 65 years or older during the study period, we identified 1·0 million cases of Parkinson's disease and 3·4 million cases of Alzheimer's disease and related dementias based on primary and secondary diagnosis billing codes.
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We also identified several common challenges.
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We identified several subgroups of the population who are particularly susceptible to temperature extremes, including persons with atrial fibrillation.
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SDI score (aHR = 1.08; 95% CI 0.96, 1.22), joint air pollution (aHR = 1.03, 95% CI 0.92, 1.16) and joint SDI with air pollution (aHR = 1.04, 95% CI 0.89, 1.22) were not associated with dementia risk.
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63/100
Evidence regarding the association of specific air pollutants with vascular dementia (VaD) risk is limited.
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Therefore, respective software was developed in-house.8,9 Segmentation results are then analysed for potential associations with disease risks and to establish reference intervals of organ size and function.10 SHIP is also used as a basis for meta-research with a particular focus on incidental MRI findings and their effects on study participants.11,12 With its large amount of standardized data and the option to internally replicate findings from SHIP-START using data of the independent SHIP-TREND, the project offers good opportunities to apply new bioinformatical tools to mine the data and gain new insights into risk factors and pathomechanisms.
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Growing evidence has linked long-term fine particulate matter (PM 2.5 ) exposure to neurological disorders.
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In cognitively unimpaired adults with increased risk for AD, increased exposure to air pollution was suggested to be associated with greater global atrophy and reduced volume and thickness in specific brain areas known to be affected in AD, thus suggesting a potential link between environmental exposures and cerebral vulnerability to AD.
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62/100
Our results showed a positive association between exposure to NOx and O 3 and hospitalization for dementia and a negative association between NO 2 exposure and hospitalization for dementia.
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Our results support an association between anemia experienced early in life and the later development of Parkinson disease.
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To review the evidence for risk factors of Creutzfeldt-Jakob disease (CJD), we pooled and reanalyzed the raw data of three case-control studies.