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The Role of Nutrition for the Aging Population: Implications for Cognition and Alzheimer's Disease
Power R, Prado-Cabrero A, Mulcahy R, Howard A, Nolan JM.. Annual review of food science and technology, 2019-03-01
Topic: Risk, prevention and care in population studies
Improved life expectancy worldwide has resulted in a significant increase in age-related diseases. Dementia is one of the fastest growing age-related diseases, with 75 million adults globally projected to develop the condition by 2030. Alzheimer's disease (AD) is the most common form of dementia and represents the most significant stage of cognitive decline. With no cure identified to date for AD, focus is being placed on preventative strategies to slow progression, minimize the burden of neurological disease, and promote healthy aging. Accumulating evidence suggests that nutrition (e.g., via fruit, vegetables, fish) is important for optimizing cognition and reducing risk of AD. This review examines the role of nutrition on cognition and AD, with specific emphasis on the Mediterranean diet (MeDi) and key nutritional components of the MeDi, namely xanthophyll carotenoids and omega-3 fatty acids. Given their selective presence in the brain and their ability to attenuate proposed mechanisms involved in AD pathogenesis (namely oxidative damage and inflammation), these nutritional compounds offer potential for optimizing cognition and reducing the risk of AD.
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APA 7th
Power, R., Prado-Cabrero, A., Mulcahy, R., Howard, A., & Nolan, J. M. (2019). The Role of Nutrition for the Aging Population: Implications for Cognition and Alzheimer's Disease. Annual review of food science and technology. https://doi.org/10.1146/annurev-food-030216-030125
Vancouver
Power R, Prado-Cabrero A, Mulcahy R, Howard A, Nolan JM. The Role of Nutrition for the Aging Population: Implications for Cognition and Alzheimer's Disease. Annual review of food science and technology. 2019. doi:10.1146/annurev-food-030216-030125. PMID: 30908950.
BibTeX
@article{power2019-30908950,
author = {Power, R. and Prado-Cabrero, A. and Mulcahy, R. and Howard, A. and Nolan, J. M.},
title = {{The Role of Nutrition for the Aging Population: Implications for Cognition and Alzheimer's Disease}},
journal = {Annual review of food science and technology},
year = {2019},
doi = {10.1146/annurev-food-030216-030125},
pmid = {30908950},
url = {https://doi.org/10.1146/annurev-food-030216-030125}
}
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Key findings
- Improved life expectancy worldwide has resulted in a significant increase in age-related diseases.
- Alzheimer's disease (AD) is the most common form of dementia and represents the most significant stage of cognitive decline.
- Accumulating evidence suggests that nutrition (e.g., via fruit, vegetables, fish) is important for optimizing cognition and reducing risk of AD.
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Study details
- Evidence strengthLow
How this study scored 38/100
Published in a peer-reviewed journal. Scored zero for study design, sample size, effect reported, studied in people and randomized / blinded because the record does not state it. We have no data on journal's citation record, times cited, citations per year, impact for its field and year, cited by studies here, still being cited, senior author's track record, institution's track record and multicenter collaboration, so those were left out: it earned 22 of the 58 points we could judge it on, which is 38 out of 100.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Annual review of food science and technology) |
| Journal's citation record | — / 4 | No journal record from OpenAlex — left out of this score |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 2 / 5 | 2019 — within 10 year(s) of the newest study here |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomized / blinded | 0 / 2 | No randomization or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | — / 7 | No citation count (not found in OpenAlex) — left out of this score |
| Citations per year | — / 5 | No citation count or no year — left out of this score |
| Impact for its field and year | — / 6 | No field-weighted citation impact (OpenAlex has none yet) — left out of this score |
| Cited by studies here | — / 6 | Not yet checked against this library's citation graph — left out of this score |
| Still being cited | — / 4 | No yearly citation counts — left out of this score |
| Senior author's track record | — / 4 | Senior author's record not available — left out of this score |
| Institution's track record | — / 3 | No institution listed in OpenAlex — left out of this score |
| Multicenter collaboration | — / 3 | Institutions not listed — left out of this score |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 30908950) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Points | 22 / 58 | Scored on 11 of 20 parts. We have no data for the rest, so they are left out: 22 of the 58 points we could judge it on is 38 out of 100. |
| Total | 38 / 100 | — |
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