This page is alzhub.org's plain-English summary of a published study, not the paper itself. It is generated from the record we hold for this study, sourced and linked below — check the original for the full text and methods.

54/100

✓ Peer-reviewed alzhub usefulness score 54 out of 100. Cognitive tests and assessment

Topic: Risk, prevention and care in population studies

Background/aims We developed and validated the Mini-Addenbrooke's Cognitive Examination (M-ACE) in dementia patients. Comparisons were also made with the Mini Mental State Examination (MMSE). Method The M-ACE was developed using Mokken scaling analysis in 117 dementia patients [behavioural variant frontotemporal dementia (bvFTD), n = 25; primary progressive aphasia (PPA), n = 49; Alzheimer's disease (AD), n = 34; corticobasal syndrome (CBS), n = 9] and validated in an independent sample of 164 dementia patients (bvFTD, n = 23; PPA, n = 82; AD, n = 38; CBS, n = 21) and 78 controls, who also completed the MMSE.

Cite this study APA, Vancouver, BibTeX · download .bib or .ris

APA 7th

Hsieh, S., McGrory, S., Leslie, F., Dawson, K., Ahmed, S., Butler, C. R., et al. (2015). The Mini-Addenbrooke's Cognitive Examination: a new assessment tool for dementia. Dementia and geriatric cognitive disorders. https://doi.org/10.1159/000366040

Vancouver

Hsieh S, McGrory S, Leslie F, Dawson K, Ahmed S, Butler CR, et al. The Mini-Addenbrooke's Cognitive Examination: a new assessment tool for dementia. Dementia and geriatric cognitive disorders. 2015. doi:10.1159/000366040. PMID: 25227877.

BibTeX

@article{hsieh2015-25227877,
  author  = {Hsieh, S. and McGrory, S. and Leslie, F. and Dawson, K. and Ahmed, S. and Butler, C. R. and Rowe, J. B. and Mioshi, E. and others},
  title   = {{The Mini-Addenbrooke's Cognitive Examination: a new assessment tool for dementia}},
  journal = {Dementia and geriatric cognitive disorders},
  year    = {2015},
  doi     = {10.1159/000366040},
  pmid    = {25227877},
  url     = {https://doi.org/10.1159/000366040}
}

Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record's author list ends in “et al.”, so not every author is named. Check the citation against the original before you use it.

Key findings

Comparisons were also made with the Mini Mental State Examination (MMSE).
Method The M-ACE was developed using Mokken scaling analysis in 117 dementia patients [behavioural variant frontotemporal dementia (bvFTD), n = 25; primary progressive aphasia (PPA), n = 49; Alzheimer's disease (AD), n = 34; corticobasal syndrome (CBS), n = 9] and validated in an independent sample of 164 dementia patients (bvFTD, n = 23; PPA, n = 82; AD, n = 38; CBS, n = 21) and 78 controls, who also completed the MMSE.
Results The M-ACE consists of 5 items with a maximum score of 30.
Two cut-offs were identified: (1) ≤25/30 has both high sensitivity and specificity, and (2) ≤21/30 is almost certainly a score to have come from a dementia patient regardless of the clinical setting.

Why it matters

Researchers developed and validated the Mini-Addenbrooke's Cognitive Examination, a five-item test, in dementia patients and compared it with the Mini Mental State Examination. This is a test development study and does not address treating, curing or preventing Alzheimer's disease.

Study details

Participants25
Evidence strengthLow

How this study scored 54/100

Published in a peer-reviewed journal. Scored zero for study design, effect reported and randomised / blinded because the record does not state it.

Component	Points	Why
Journal tier	7 / 10	Tier 3 — peer-reviewed journal (Dementia and geriatric cognitive disorders)
Journal's citation record	1 / 4	Dementia and Geriatric Cognitive Disorders: journal h-index 149 (OpenAlex, 2026-10-29)
Study design	0 / 12	No study design recorded — scores zero, not guessed (not stated in the record — scored 0)
Strength of evidence	1 / 5	Rated “low” in our summary
Peer-review validation	10 / 10	Peer-reviewed. Published as an article in a named peer-reviewed journal.
How recent	1 / 5	2015 — within 20 year(s) of the newest study here
Sample size	1 / 4	25 participants
Effect reported	0 / 3	No effect size reported — scores zero (not stated in the record — scored 0)
Studied in people	3 / 3	Studied in people (participant count stated)
Randomised / blinded	0 / 2	No randomisation or blinding stated — scores zero (not stated in the record — scored 0)
Times cited	5 / 7	Cited 279 times (OpenAlex, 2026-10-10)
Citations per year	4 / 5	21.5 citations a year over 13 year(s) since 2015
Impact for its field and year	4 / 6	Cited 8.8× the average for papers of its field and year (OpenAlex FWCI)
Cited by studies here	1 / 6	Cited by 2 other studies in this library
Still being cited	3 / 4	Cited 61 times in 2024–2026 (2026 still in progress; OpenAlex)
Senior author's track record	4 / 4	Last-listed author John R. Hodges: h-index 107 (OpenAlex, whole career)
Institution's track record	2 / 3	University of Oxford: institution h-index 2,205 (OpenAlex)
Multi-centre collaboration	3 / 3	OpenAlex lists 10 institution(s) in 2 countries
Indexed in PubMed	2 / 2	Indexed in PubMed (PMID 25227877)
Free to read	2 / 2	Free to read
Total	54 / 100	—

What each of these 20 components measures, and what this score is not →

Read the original

Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).

Studies this one cites

Referenced by this study and also in the alzhub library, so you can read them here.

Later studies that cite this one

2 studies in the alzhub library list this one in their references.

Related studies in Cognitive tests and assessment

Also tagged “examination”

840 studies in the library carry the topic tag “examination”; these are this study's neighbours in a fixed, alphabetical-by-hash tour of them, not the closest in content. All 840 tagged studies.

Similar studies

More on Cognitive tests and assessment

See all studies in Cognitive tests and assessment →