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How Do Scores on the ADAS-Cog, MMSE, and CDR-SOB Correspond?
Balsis S, Benge JF, Lowe DA, Geraci L, Doody RS.. The Clinical neuropsychologist, 2015-11-30
Topic: Risk, prevention and care in population studies
Objective Clinicians and researchers who measure cognitive dysfunction often use the Alzheimer's Disease Assessment Scale--Cognitive Subscale (ADAS-Cog), the Mini-Mental State Examination (MMSE), or the Clinical Dementia Rating scale (CDR-SOB). But, the use of different measures can make it difficult to compare data across patients or studies. What is needed is a simple chart that shows how scores on these three important measures correspond to each other.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Balsis, S., Benge, J. F., Lowe, D. A., Geraci, L., & Doody, R. S. (2015). How Do Scores on the ADAS-Cog, MMSE, and CDR-SOB Correspond? The Clinical neuropsychologist. https://doi.org/10.1080/13854046.2015.1119312
Vancouver
Balsis S, Benge JF, Lowe DA, Geraci L, Doody RS. How Do Scores on the ADAS-Cog, MMSE, and CDR-SOB Correspond? The Clinical neuropsychologist. 2015. doi:10.1080/13854046.2015.1119312. PMID: 26617181.
BibTeX
@article{balsis2015-26617181,
author = {Balsis, S. and Benge, J. F. and Lowe, D. A. and Geraci, L. and Doody, R. S.},
title = {{How Do Scores on the ADAS-Cog, MMSE, and CDR-SOB Correspond?}},
journal = {The Clinical neuropsychologist},
year = {2015},
doi = {10.1080/13854046.2015.1119312},
pmid = {26617181},
url = {https://doi.org/10.1080/13854046.2015.1119312}
}
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Key findings
- But, the use of different measures can make it difficult to compare data across patients or studies.
- What is needed is a simple chart that shows how scores on these three important measures correspond to each other.
- Methods Using data from 1709 participants from the Alzheimer's Disease Neuroimaging Initiative and item response theory-based statistics, we analyzed how scores on each measure, the ADAS-Cog, the MMSE, and the CDR-SOB, correspond.
- Results Results indicated multiple inflections in CDR-SOB and ADAS-Cog scores within a given MMSE score, suggesting that the CDR-SOB and ADAS-Cog are more precise in measuring the severity of cognitive dysfunction than the MMSE.
Why it matters
This work used data from 1709 participants to build a chart showing how scores on the ADAS-Cog, MMSE and CDR-SOB correspond to each other. It is about making it easier to compare cognitive test scores across patients and studies, not about treating or preventing the disease.
Study details
- Participants1,709
- Evidence strengthLow
How this study scored 49/100
Published in a peer-reviewed journal. Scored zero for study design, effect reported and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (The Clinical neuropsychologist) |
| Journal's citation record | 1 / 4 | The Clinical Neuropsychologist: journal h-index 128 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 1 / 5 | 2015 — within 20 year(s) of the newest study here |
| Sample size | 3 / 4 | 1,709 participants |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 5 / 7 | Cited 128 times (OpenAlex, 2026-10-10) |
| Citations per year | 3 / 5 | 9.8 citations a year over 13 year(s) since 2015 |
| Impact for its field and year | 2 / 6 | Cited 2.4× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 2 / 6 | Cited by 9 other studies in this library |
| Still being cited | 2 / 4 | Cited 42 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 3 / 4 | Last-listed author Rachelle Smith Doody: h-index 97 (OpenAlex, whole career) |
| Institution's track record | 2 / 3 | Baylor College of Medicine: institution h-index 1,607 (OpenAlex) |
| Multi-centre collaboration | 2 / 3 | OpenAlex lists 4 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 26617181) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Total | 49 / 100 | — |
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