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Bridging the gap: A conversion framework for CDR-SB and MoCA scores in Alzheimer's disease and related dementia
Babak Haji, Quanwu Zhang, Amir Abbas Tahami Monfared. The Journal of Prevention of Alzheimer s Disease, 2025-06-07
Topic: Risk, prevention and care in population studies
CDR-SB and MoCA scores showed strong inverse correlation (Spearman's ρ = -0.68; p < 0.001). Crosswalk tables demonstrated good agreement across the cognitive spectrum and performed consistently in the full cohort and an AD-specific subgroup. This study provides the first validated, bidirectional CDR-SB-MoCA crosswalk, supporting data harmonization and consistent interpretation of cognitive severity across research and clinical settings.
Key findings
- CDR-SB and MoCA scores showed strong inverse correlation (Spearman's ρ = -0.68; p < 0.001).
- Crosswalk tables demonstrated good agreement across the cognitive spectrum and performed consistently in the full cohort and an AD-specific subgroup.
- This study provides the first validated, bidirectional CDR-SB-MoCA crosswalk, supporting data harmonization and consistent interpretation of cognitive severity across research and clinical settings.
Why it matters
This study provides a validated bidirectional crosswalk between CDR-SB and MoCA scores, which were strongly inversely correlated. It supports harmonizing cognitive severity data across research and clinical settings, but it does not address treating, curing, or preventing dementia.
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Study details
- Study designcross-sectional
- Participants23,717
- Evidence strengthModerate
How this study scored 49/100
Published in a peer-reviewed journal, and it is a snapshot of people at one point in time. Scored zero for effect reported and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (The Journal of Prevention of Alzheimer s Disease) |
| Journal's citation record | 0 / 4 | The Journal of Prevention of Alzheimer s Disease: journal h-index 63 (OpenAlex, 2026-10-29) |
| Study design | 4 / 12 | A snapshot of people at one point in time |
| Strength of evidence | 3 / 5 | Rated “moderate” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 4 / 5 | 2025 — within 3 year(s) of the newest study here |
| Sample size | 4 / 4 | 23,717 participants |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 1 / 7 | Cited 3 times (OpenAlex, 2026-10-10) |
| Citations per year | 1 / 5 | 1.0 citations a year over 3 year(s) since 2025 |
| Impact for its field and year | 2 / 6 | Cited 1.9× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 1 / 6 | Cited by 1 other studies in this library |
| Still being cited | 1 / 4 | Cited 3 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 2 / 4 | Last-listed author Amir Abbas Tahami Monfared: h-index 20 (OpenAlex, whole career) |
| Institution's track record | 1 / 3 | McGill University: institution h-index 1,373 (OpenAlex) |
| Multi-centre collaboration | 1 / 3 | OpenAlex lists 2 institution(s) in 2 countries |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 40484799) |
| Free to read | 2 / 2 | Free to read |
| Total | 49 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
- DOI: 10.1016/j.tjpad.2025.100226
- PubMed: 40484799
- Original source →
- Free full text: The Journal of Prevention of Alzheimer s Disease →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. Check the citation against the original before you use it.
APA 7th
Haji, B., Zhang, Q., & Monfared, A. A. T. (2025). Bridging the gap: A conversion framework for CDR-SB and MoCA scores in Alzheimer's disease and related dementia. The Journal of Prevention of Alzheimer s Disease. https://doi.org/10.1016/j.tjpad.2025.100226
Vancouver
Haji B, Zhang Q, Monfared AAT. Bridging the gap: A conversion framework for CDR-SB and MoCA scores in Alzheimer's disease and related dementia. The Journal of Prevention of Alzheimer s Disease. 2025. doi:10.1016/j.tjpad.2025.100226. PMID: 40484799.
BibTeX
@article{haji2025-40484799,
author = {Haji, Babak and Zhang, Quanwu and Monfared, Amir Abbas Tahami},
title = {{Bridging the gap: A conversion framework for CDR-SB and MoCA scores in Alzheimer's disease and related dementia}},
journal = {The Journal of Prevention of Alzheimer s Disease},
year = {2025},
doi = {10.1016/j.tjpad.2025.100226},
pmid = {40484799},
url = {https://doi.org/10.1016/j.tjpad.2025.100226}
}
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