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Frontotemporal dementia: patient characteristics, cognition, and behaviour
Diehl J, Kurz A.. International journal of geriatric psychiatry, 2002-10-01
Topic: Risk, prevention and care in population studies
Objectives To describe sociodemographic data of patients with frontotemporal dementia (FTD), to compare the cognitive profile of patients with FTD with that of severity-matched patients with Alzheimer's disease using the CERAD neuropsychological battery (CERAD-NP), to investigate the frequency of behavioural disturbances, and to examine the relation between FTD-specific non-cognitive behavioural symptoms of patients with FTD with age and sex. Methods Fifty outpatients were diagnosed with FTD according to the Lund-Manchester consensus criteria. Cognitive impairment was assessed in 30 patients using the CERAD-NP. Severity of dementia was rated on the Clinical Dementia Rating (CDR). Eleven non-cognitive symptoms were rated by severity. To compare CERAD-NP results between patients with FTD and AD, 30 patients with AD were matched for age, sex, and global severity of cognitive performance. Results The average age at onset of first symptoms was 57.8 years. Eighteen patients (36%) had a positive family history of dementia. On the CERAD-NP patients with FTD performed significantly better than patients with AD on word list learning, delayed verbal recall and visuoconstruction (p Conclusions The CERAD-NP is a valuable clinical instrument for the cognitive evaluation of patients with suspected FTD. Complementary short tests of attention and executive function may be recommended. To enhance diagnostic sensitivity informant interviews should focus on non-cognitive behavioural changes, taking advantage of standardised questionnaires.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Diehl, J., & Kurz, A. (2002). Frontotemporal dementia: patient characteristics, cognition, and behaviour. International journal of geriatric psychiatry. https://doi.org/10.1002/gps.709
Vancouver
Diehl J, Kurz A. Frontotemporal dementia: patient characteristics, cognition, and behaviour. International journal of geriatric psychiatry. 2002. doi:10.1002/gps.709. PMID: 12325050.
BibTeX
@article{diehl2002-12325050,
author = {Diehl, J. and Kurz, A.},
title = {{Frontotemporal dementia: patient characteristics, cognition, and behaviour}},
journal = {International journal of geriatric psychiatry},
year = {2002},
doi = {10.1002/gps.709},
pmid = {12325050},
url = {https://doi.org/10.1002/gps.709}
}
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Key findings
- To compare CERAD-NP results between patients with FTD and AD, 30 patients with AD were matched for age, sex, and global severity of cognitive performance.
- Results The average age at onset of first symptoms was 57.8 years.
- On the CERAD-NP patients with FTD performed significantly better than patients with AD on word list learning, delayed verbal recall and visuoconstruction (p Conclusions The CERAD-NP is a valuable clinical instrument for the cognitive evaluation of patients with suspected FTD.
Why it matters
This study described characteristics of 50 patients with frontotemporal dementia and compared their cognitive profile with severity-matched patients with Alzheimer's disease. It concerns frontotemporal dementia and cognitive testing, not Alzheimer's treatment, cure or prevention.
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Study details
- Participants30
- Evidence strengthLow
How this study scored 43/100
Published in a peer-reviewed journal. Scored zero for study design, effect reported and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (International journal of geriatric psychiatry) |
| Journal's citation record | 2 / 4 | International Journal of Geriatric Psychiatry: journal h-index 190 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 1 / 5 | 2002 — older than 20 years, still counted |
| Sample size | 1 / 4 | 30 participants |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 4 / 7 | Cited 91 times (OpenAlex, 2026-10-10) |
| Citations per year | 2 / 5 | 3.5 citations a year over 26 year(s) since 2002 |
| Impact for its field and year | 3 / 6 | Cited 4.9× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 2 / 6 | Cited by 4 other studies in this library |
| Still being cited | 1 / 4 | Cited 5 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 3 / 4 | Last-listed author Alexander Kurz: h-index 65 (OpenAlex, whole career) |
| Institution's track record | 1 / 3 | Technical University of Munich: institution h-index 1,092 (OpenAlex) |
| Multi-centre collaboration | 0 / 3 | OpenAlex lists 1 institution(s) in 1 country — scores zero (affiliation lists can be incomplete) |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 12325050) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Total | 43 / 100 | — |
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