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Cognitive impairment predicts poststroke death in long-term follow-up
Oksala NK, Jokinen H, Melkas S, Oksala A, Pohjasvaara T, Hietanen M, Vataja R, Kaste M et al.. Journal of neurology, neurosurgery, and psychiatry, 2009-07-19
Topic: Risk, prevention and care in population studies
Background Poststroke global cognitive decline and dementia have been related to poor long-term survival. Whether deficits in specific cognitive domains are associated with long-term survival in patients with ischaemic stroke is not known in detail. Methods Patients with acute stroke subjected to comprehensive neuropsychological evaluation were included in the study (n = 409) and followed up for up to 12 years.
Key findings
- Whether deficits in specific cognitive domains are associated with long-term survival in patients with ischaemic stroke is not known in detail.
- Methods Patients with acute stroke subjected to comprehensive neuropsychological evaluation were included in the study (n = 409) and followed up for up to 12 years.
- Results In Kaplan-Meier analysis, impairments in following cognitive domains predicted poor poststroke survival (estimated years): executive functions (48.2%) (5.8 vs 10.1 years, p<0.0001), memory (59.9%) (6.8 vs 9.3 years, p = 0.009), language (28.9%) (5.3 vs 8.6 years, p = 0.004) and visuospatial/constructional abilities (55.2%) (5.6 vs 10.1 years, p<0.0001).
Why it matters
In 409 patients with acute stroke followed for up to 12 years, impairments in certain cognitive domains predicted poorer long-term survival. This describes cognitive impairment as a marker of post-stroke death risk, but it does not test any treatment for Alzheimer's disease.
Study details
- Participants409
- Effect size48.2%
- Evidence strengthLow
How this study scored 51/100
Published in a peer-reviewed journal. Scored zero for study design and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Journal of neurology, neurosurgery, and psychiatry) |
| Journal's citation record | 3 / 4 | Journal of Neurology Neurosurgery & Psychiatry: journal h-index 336 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 1 / 5 | 2009 — within 20 year(s) of the newest study here |
| Sample size | 2 / 4 | 409 participants |
| Effect reported | 2 / 3 | Effect reported as a number, without an interval or test |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 5 / 7 | Cited 142 times (OpenAlex, 2026-10-10) |
| Citations per year | 2 / 5 | 7.5 citations a year over 19 year(s) since 2009 |
| Impact for its field and year | 3 / 6 | Cited 5.9× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 2 / 6 | Cited by 5 other studies in this library |
| Still being cited | 2 / 4 | Cited 23 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 3 / 4 | Last-listed author Timo Erkinjuntti: h-index 52 (OpenAlex, whole career) |
| Institution's track record | 1 / 3 | University of Helsinki: institution h-index 1,201 (OpenAlex) |
| Multi-centre collaboration | 2 / 3 | OpenAlex lists 4 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 19620138) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Total | 51 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
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Cite this study APA, Vancouver, BibTeX · download .bib or .ris
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record's author list ends in “et al.”, so not every author is named. Check the citation against the original before you use it.
APA 7th
Oksala, N. K., Jokinen, H., Melkas, S., Oksala, A., Pohjasvaara, T., Hietanen, M., et al. (2009). Cognitive impairment predicts poststroke death in long-term follow-up. Journal of neurology, neurosurgery, and psychiatry. https://doi.org/10.1136/jnnp.2009.174573
Vancouver
Oksala NK, Jokinen H, Melkas S, Oksala A, Pohjasvaara T, Hietanen M, et al. Cognitive impairment predicts poststroke death in long-term follow-up. Journal of neurology, neurosurgery, and psychiatry. 2009. doi:10.1136/jnnp.2009.174573. PMID: 19620138.
BibTeX
@article{oksala2009-19620138,
author = {Oksala, N. K. and Jokinen, H. and Melkas, S. and Oksala, A. and Pohjasvaara, T. and Hietanen, M. and Vataja, R. and Kaste, M. and others},
title = {{Cognitive impairment predicts poststroke death in long-term follow-up}},
journal = {Journal of neurology, neurosurgery, and psychiatry},
year = {2009},
doi = {10.1136/jnnp.2009.174573},
pmid = {19620138},
url = {https://doi.org/10.1136/jnnp.2009.174573}
}
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