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60/100

✓ Peer-reviewed alzhub usefulness score 60 out of 100. Prevention trials

Topic: Risk, prevention and care in population studies

Plain-language summary

In multi-adjusted models, higher adherence to the EAT-Lancet diet was associated with higher total mean cortical thickness, and thicker cortex in Alzheimer's disease-signature regions, while a higher adherence to the MeDi was associated with better cognitive performance. The results indicate the beneficial effects of both the EAT-Lancet and the MeDi on brain health. HIGHLIGHTS: There were no indications of detrimental effects of adhering to the EAT-Lancet diet. Adhering to the EAT-Lancet planetary health diet was associated with thicker cortex. Results confirm links between the Mediterranean diet and better cognitive function.

Cite this study APA, Vancouver, BibTeX · download .bib or .ris

APA 7th

Samuelsson, J., Stubbendorff, A., Marseglia, A., Lindberg, O. E., Dartora, C. M., Shams, S., et al. (2025). A comparative study of the EAT‐Lancet diet and the Mediterranean diet in relation to neuroimaging biomarkers and cognitive performance. Alzheimer s & Dementia. https://doi.org/10.1002/alz.70191

Vancouver

Samuelsson J, Stubbendorff A, Marseglia A, Lindberg OE, Dartora CM, Shams S, et al. A comparative study of the EAT‐Lancet diet and the Mediterranean diet in relation to neuroimaging biomarkers and cognitive performance. Alzheimer s & Dementia. 2025. doi:10.1002/alz.70191. PMID: 40302043.

BibTeX

@article{samuelsson2025-40302043,
  author  = {Samuelsson, Jessica and Stubbendorff, Anna and Marseglia, Anna and Lindberg, Olof E. and Dartora, Caroline Machado and Shams, Sara and Cedrés, Nira and Kern, Silke and others},
  title   = {{A comparative study of the EAT‐Lancet diet and the Mediterranean diet in relation to neuroimaging biomarkers and cognitive performance}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz.70191},
  pmid    = {40302043},
  url     = {https://doi.org/10.1002/alz.70191}
}

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How to read this study

Design: this is a follow-up (cohort) study. People are observed over time and not assigned to anything, so an association can reflect other differences between groups. Look at how long follow-up lasted, how many dropped out, and whether the authors adjusted for age, education and other health conditions.
Size: the record lists 615 participants. Ask whether that is enough for the question, and who they were.
Effect: the record gives no effect size, so the summary above cannot say how large any difference was.

What the evidence grade means here

This page is graded moderate. alzhub.org assigns the grade automatically from keywords in the abstract, not from reading the paper. Moderate means the abstract mentions a cohort, case-control or longitudinal design. It can add at most 5 of the 100 points in the study score, and it is a label about design, not a verdict on whether the findings are true.

New to reading papers? Six questions to ask of any Alzheimer’s study · how we score.

Key findings

In multi-adjusted models, higher adherence to the EAT-Lancet diet was associated with higher total mean cortical thickness, and thicker cortex in Alzheimer's disease-signature regions, while a higher adherence to the MeDi was associated with better cognitive performance.
The results indicate the beneficial effects of both the EAT-Lancet and the MeDi on brain health.
HIGHLIGHTS: There were no indications of detrimental effects of adhering to the EAT-Lancet diet.
Adhering to the EAT-Lancet planetary health diet was associated with thicker cortex.
Results confirm links between the Mediterranean diet and better cognitive function.

Why it matters

This observational study found that closer adherence to the EAT-Lancet diet was linked to thicker cortex, including in Alzheimer's-related regions, while closer adherence to the Mediterranean diet was linked to better cognitive performance. It cannot show that either diet prevents or treats Alzheimer's disease.

New to this subject? Start with our plain-English guide: Prevention →

Study details

Study designcohort study
Participants615
Evidence strengthModerate

How this study scored 60/100

Published in a peer-reviewed journal, and it is a cohort study following people over time. Scored zero for effect reported and randomized / blinded because the record does not state it.

Component	Points	Why
Journal tier	7 / 10	Tier 3 — peer-reviewed journal (Alzheimer s & Dementia)
Journal's citation record	2 / 4	Alzheimer s & Dementia: journal h-index 228 (OpenAlex, 2026-10-29)
Study design	7 / 12	A cohort study following people over time
Strength of evidence	3 / 5	Rated “moderate” in our summary
Peer-review validation	10 / 10	Peer-reviewed. Published as an article in a named peer-reviewed journal.
How recent	4 / 5	2025 — within 3 year(s) of the newest study here
Sample size	2 / 4	615 participants
Effect reported	0 / 3	No effect size reported — scores zero (not stated in the record — scored 0)
Studied in people	3 / 3	Studied in people (participant count stated)
Randomized / blinded	0 / 2	No randomization or blinding stated — scores zero (not stated in the record — scored 0)
Times cited	2 / 7	Cited 9 times (OpenAlex, 2026-10-10)
Citations per year	2 / 5	3.0 citations a year over 3 year(s) since 2025
Impact for its field and year	3 / 6	Cited 7.6× the average for papers of its field and year (OpenAlex FWCI)
Cited by studies here	0 / 6	No other study in this library cites it
Still being cited	1 / 4	Cited 9 times in 2024–2026 (2026 still in progress; OpenAlex)
Senior author's track record	4 / 4	Last-listed author Ingmar Gr. Skoog: h-index 105 (OpenAlex, whole career)
Institution's track record	3 / 3	Stanford University: institution h-index 2,684 (OpenAlex)
Multicenter collaboration	3 / 3	OpenAlex lists 11 institution(s) in 3 countries
Indexed in PubMed	2 / 2	Indexed in PubMed (PMID 40302043)
Free to read	2 / 2	Free to read
Total	60 / 100	—

What each of these 20 components measures, and what this score is not →

Read the original

Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).

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