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Research

30,580 Alzheimer's and dementia studies in plain English, each scored out of 100.

Find studies

Showing 401–425 of 559 studies · free to read (page 17 of 23) · 30,580 in the whole library · How the 0–100 score works

Download bibliography of the first 500 of these studies, in this order: BibTeX (.bib) · RIS (.ris)

Showing 559 studies tagged small — clear

Browse by subject, author or institution

Each number is how many studies that link shows, with your other filters kept.

Subjects

Authors

Names as each record prints them; the same person can appear under two spellings.

Institutions

From OpenAlex; 16,054 studies have no institution on record and are not counted here.

A note on reading research. One study is rarely the final word.

We try to note the size of a study, whether it was in humans or animals, and how early-stage the finding is. If a summary here doesn't make that clear, treat it with extra caution and check the original source.

Blood-Brain Barrier Dysfunction Precedes Cognitive Decline and Neurodegeneration in Diabetic Insulin Resistant Mouse Model: An Implication for Causal Link

✓ Peer-reviewed alzhub usefulness score 44 out of 100. Frontiers in aging neuroscience 2017-12-01

Diabetic insulin resistance and pro-diabetic diet are reported to increase dementia risk through unknown mechanisms. 5 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Spontaneous white matter damage, cognitive decline and neuroinflammation in middle-aged hypertensive rats: an animal model of early-stage cerebral small vessel disease

✓ Peer-reviewed alzhub usefulness score 44 out of 100. Acta neuropathologica communications 2014-12-18

Our results indicate that SHR share behavioral and neuropathological characteristics with human cSVD patients and further undergird the relevance of immune responses for the initiation and progression of cSVD. 4 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Advances in arterial spin labelling MRI methods for measuring perfusion and collateral flow

✓ Peer-reviewed alzhub usefulness score 44 out of 100. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2017-06-09

With the publication in 2015 of the consensus statement by the perfusion study group of the International Society for Magnetic Resonance in Medicine (ISMRM) and the EU-COST action 'ASL in dementia' on the implementation of arterial spin labelling MRI (ASL) in a clinical setting, the development of ASL can be considered to have become mature and ready for clinical prime-time. 5 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Ischemic stroke of unclear aetiology: a case-by-case analysis and call for a multi-professional predictive, preventive and personalised approach

✓ Peer-reviewed alzhub usefulness score 44 out of 100. The EPMA journal 2022-11-17

In sub-populations such as diabetes mellitus type 2, proliferative diabetic retinopathy is an independent predictor of ischemic stroke. 5 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Abnormal insula functional network is associated with episodic memory decline in amnestic mild cognitive impairment

✓ Peer-reviewed alzhub usefulness score 44 out of 100. NeuroImage 2012-07-06

Abnormalities of functional connectivity in the default mode network (DMN) recently have been reported in patients with amnestic mild cognitive impairment (aMCI), Alzheimer's disease (AD) or other psychiatric diseases. 4 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Convergence between Microglia and Peripheral Macrophages Phenotype during Development and Neuroinflammation

✓ Peer-reviewed alzhub usefulness score 44 out of 100. The Journal of neuroscience : the official journal of the Society for Neuroscience 2019-12-09

Differently from other myeloid cells, microglia derive exclusively from precursors originating within the yolk sac and migrate to the CNS under development, without any contribution from fetal liver or postnatal hematopoiesis. 4 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Microglia influence host defense, disease, and repair following murine coronavirus infection of the central nervous system

✓ Peer-reviewed alzhub usefulness score 44 out of 100. Glia 2020-05-25

The present study examines functional contributions of microglia in host defense, demyelination, and remyelination following infection of susceptible mice with a neurotropic coronavirus. 4 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Cerebral Blood Flow and Amyloid-β Interact to Affect Memory Performance in Cognitively Normal Older Adults

✓ Peer-reviewed alzhub usefulness score 44 out of 100. Frontiers in aging neuroscience 2017-06-08

Cerebral blood flow (CBF) alterations and amyloid-β (Aβ) accumulation have been independently linked to cognitive deficits in older adults at risk for dementia. 4 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Integrated bioinformatics analysis and biological experiments to identify key immune genes in vascular dementia

✓ Peer-reviewed alzhub usefulness score 44 out of 100. Frontiers in Immunology 2025-03-24

The results of gene set enrichment and gene set variation analyses indicated that immune-related pathways were upregulated in patients with VaD. 4 key findings →

Participants: 1,620 Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

The Role of Oxidative Stress and Inflammation in the Pathogenesis and Treatment of Vascular Dementia

✓ Peer-reviewed alzhub usefulness score 44 out of 100. Cells 2025-04-17

Vascular dementia (VaD) is a heterogeneous group of brain disorders caused by cerebrovascular pathologies and the second most common cause of dementia, accounting for over 20% of cases and posing an important global health concern. 5 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Assessment of localized brain regions correlated with MMSE using VBM analysis of structural MRI in a Japanese sample

✓ Peer-reviewed alzhub usefulness score 44 out of 100. Neuroimage Reports 2025-04-28

The global aging population has led to a significant rise in dementia and cognitive decline, with Alzheimer's disease as the primary cause. 5 key findings →

Design: cross-sectional Participants: 510 Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

Circulating Brain-Related miRNAs as Predictors of Postoperative Delirium in Cardiac Surgery Patients

✓ Peer-reviewed alzhub usefulness score 44 out of 100. International Journal of Molecular Sciences 2025-09-17

Delirium is a neuropsychiatric syndrome that is pathophysiologically related to both mental (dementia, depression) and physical illness. 5 key findings →

Participants: 224 Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Anatomical differences between CBS-corticobasal degeneration and CBS-Alzheimer's disease

✓ Peer-reviewed alzhub usefulness score 43 out of 100. Movement disorders : official journal of the Movement Disorder Society 2010-07-01

We compare patterns of gray matter loss on MRI in subjects presenting as corticobasal syndrome (CBS) with Alzheimer disease pathology (CBS-AD) to those presenting as CBS with corticobasal degeneration pathology (CBS-CBD). 4 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

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Where “Free full text” comes from

Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled.

How the 0–100 score works — and why some entries are capped

This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.

  • Journal tier up to 10 pts
  • Journal's citation record up to 4 pts
  • Study design up to 12 pts
  • Strength of evidence up to 5 pts
  • Peer-review validation up to 10 pts
  • How recent up to 5 pts
  • Sample size up to 4 pts
  • Effect reported up to 3 pts
  • Studied in people up to 3 pts
  • Randomised / blinded up to 2 pts
  • Times cited up to 7 pts
  • Citations per year up to 5 pts
  • Impact for its field and year up to 6 pts
  • Cited by studies here up to 6 pts
  • Still being cited up to 4 pts
  • Senior author's track record up to 4 pts
  • Institution's track record up to 3 pts
  • Multi-centre collaboration up to 3 pts
  • Indexed in PubMed up to 2 pts
  • Free to read up to 2 pts

Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.

Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.

We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.

The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.

See the whole rubric drawn out → — four charts covering all 30,580 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.

What this library is — and isn't

This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 30,580 records, built mostly from automated pulls of Europe PMC (64.7% of the library) and OpenAlex (16.6%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.

1,037 records (3.4% of the library) are not peer-reviewed — 964 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.

See the full, machine-readable breakdown of this library's coverage →

Newest studies, as a dated timeline →    Atom feed    Where this research is being discussed: events