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Home › Research › Topic

Inflammation, microglia and astrocytes

730 studies in this group. A computer grouped them by what their titles and summaries are about, not by a hand-made list. The name describes most of the group, not every study in it.

Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.

Highest usefulness score first. Studies without a score come last.

  1. APOE4 promotes cerebrovascular fibrosis and amyloid deposition via a pericyte-to-myofibroblast transition

    ⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. bioRxiv : the preprint server for biology 2025-09-09 Vascular contributions

    Cerebrovascular disease is a major but poorly understood feature of Alzheimer's disease (AD).

  2. The Silent Saboteur: How Mitochondria Shape the Long-Term Fate of the Injured Brain

    ⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. bioRxiv : the preprint server for biology 2025-03-27 Biomarkers

    Traumatic brain injury (TBI) is a major risk factor for neurodegenerative diseases, including Alzheimer's disease (AD), yet the mechanistic link remains unclear.

  3. Impaired microglial phagocytosis promotes seizure development

    ⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. bioRxiv : the preprint server for biology 2024-01-02 TREM2 and immune genetics

    In the central nervous system, triggering receptor expressed on myeloid cells 2 (TREM2) is exclusively expressed by microglia and is critical for microglial proliferation, migration, and phagocytosis.

  4. INPP5D/SHIP1 regulates inflammasome activation in human microglia

    ⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. bioRxiv : the preprint server for biology 2023-02-26 Inflammation and the immune system

    Microglia and neuroinflammation are implicated in the development and progression of Alzheimer's disease (AD).

  5. ADAMTS13 maintains cerebrovascular integrity to ameliorate Alzheimer-like pathology

    ⚠ Retracted — do not rely on it alzhub usefulness score 12 out of 100. PLoS biology 2019-06-11 Vascular contributions

    Blood-brain barrier (BBB) defects and cerebrovascular dysfunction contribute to amyloid-β (Aβ) brain accumulation and drive Alzheimer disease (AD) pathology.

From across this topic

10 of the 730 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.

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