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Home › Research › Topics › mice

mice

1,163 studies tagged mice, dated 1986-01-01 to 2026-09-25. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. What Do Sugar, Gila Monsters, and the Therapeutic Dance Have in Common With GLP-1RA, Stroke, and Dementia? 2026-09-25
  2. Myo-inositol as a spectroscopic marker of neuroinflammation in frontotemporal lobar degeneration 2026-09-20
  3. Laromestrocel preserves brain volume and cognitive function in Alzheimers disease by inhibiting neuroinflammation 2026-09-17

Studies

1,163 studies carry this tag.

Date range

1986 to 2026

Top journals

  • The Journal of biological chemistry 109
  • The Journal of neuroscience : the official journal of the Society for Neuroscience 42
  • Proceedings of the National Academy of Sciences of the United States of America 39
  • Neuron 28
  • Nature 23

365 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Chronic Exposure to Thermally Processed Food-Derived Carbon Polymers Accelerated Neuroinflammation in Alzheimer Disease Mice through Microbe–Gut–Brain Axis

    ✓ Peer-reviewed alzhub usefulness score 37 out of 100. Journal of Agricultural and Food Chemistry 2026-01-28 Inflammation and the immune system

    Processed foods are increasingly associated with the prevalence of neurodegenerative diseases, including Alzheimer disease (AD).

  2. Microglial histone H3K18 crotonylation promotes STAT1 expression and induces cognitive deficit in Alzheimer disease

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Frontiers in Immunology 2026-01-27 Inflammation and the immune system

    Hippocampal pan-histone H3 crotonylation (H3Kcr) and H3K18cr were significantly upregulated in both 5xFAD and Aβ42-injected mice compared to controls.

  3. Evidence for reduced somatic T-cell receptor sequence diversity profiles among Midwestern Amish in an aging cohort study

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Annals of human genetics 2026-01-26 Tau biomarkers

    Late-onset Alzheimer disease (LOAD), the most common form of dementia among older adults, is a neurodegenerative disease characterized by brain amyloid-β (Aβ) plaque deposition and neurofibrillary tangles.

  4. From Evasion to Collapse: The Kinetic Cascade of TDP-43 and the Failure of Proteostasis

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. International Journal of Molecular Sciences 2026-01-23 Brain tissue and pathology

    Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are devastating neurodegenerative diseases that, despite the availability of symptomatic and modestly beneficial treatments, still lack therapies capable of halting disease progression.

  5. Peripheral cancer attenuates amyloid pathology in Alzheimer's disease via cystatin-c activation of TREM2

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Cell 2026-01-22 Laboratory science

    Alzheimer's disease (AD) and cancer are among the most devastating diseases worldwide.

  6. Electrical stimulation of the vagus nerve improves amyloid pathology in delirium superimposed on dementia

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Bioelectronic Medicine 2026-01-16 Inflammation and the immune system

    In AD-like mice surgery induced acute changes in amyloid-β; perioperative treatment with pVNS effectively reduced amyloid-β load, plaque sphericity, and neuronal loss.

  7. Defining the Intestinal eCBome and Oxylipin Signaling Systems in a TDP‐43 Mouse Model of Frontotemporal Dementia

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. The FASEB Journal 2026-01-12 Brain tissue and pathology

    Frontotemporal dementia (FTD) is a group of early onset and progressive disorders, characterized by degeneration in the frontal and temporal lobes, and subsequent deterioration in cognition, personality, social behavior, and language, with aggregates of the RNA-binding protein TDP-43 being present in ~45% of the cases.

  8. HOPS disruption impairs APP trafficking and processing, promoting exosomal secretion of APP-CTFs

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Neurobiology of Disease 2026-01-10 Risk genes beyond APOE

    Amyloid precursor protein (APP) is a key player in various neuronal functions but also the source for toxic Aβ that accumulates in the brain of Alzheimer patients.

  9. Restoration of progranulin by engineered hematopoietic stem cell–derived microglia corrects phenotypes of granulin knockout mice

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Science Translational Medicine 2026-01-07 Inflammation and the immune system

    Autologous hematopoietic stem/progenitor cell (HSC)–gene therapy (GT) represents a promising therapeutic option for progranulin (PGRN)–related neurodegenerative diseases due to mutations in the PGRN encoding gene ( GRN ), such as frontotemporal dementia (FTD) and neuronal ceroid lipofuscinosis 11 (CLN11).

  10. GASDERMIN D-mediated pyroptosis as a therapeutic target in TAU-dependent frontotemporal dementia mouse model

    ✓ Peer-reviewed alzhub usefulness score 42 out of 100. Journal of Biomedical Science 2026-01-05 Lewy body dementia

    AD patients exhibited increased expression of pyroptosis-related genes, supporting the involvement of pyroptosis in neurodegeneration.

  11. TDP-43-mediated alternative polyadenylation is associated with a reduction in VPS35 and VPS29 expression in frontotemporal dementia

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. PLoS Biology 2026-01-05 Lewy body dementia

    TAR DNA-binding protein 43 (TDP-43) dysfunction is a hallmark of several neurodegenerative diseases, including frontotemporal dementia, amyotrophic lateral sclerosis, and Alzheimer's disease.

  12. Propyl Gallate Attenuates Methylglyoxal-Induced Alzheimer-like Cognitive Deficits and Neuroinflammation in Mice

    ✓ Peer-reviewed alzhub usefulness score 42 out of 100. International Journal of Molecular Sciences 2026-01-04 Inflammation and the immune system

    Methylglyoxal (MG), a reactive dicarbonyl metabolite associated with diabetes and metabolic disorders, contributes to carbonyl stress, neuroinflammation, and Alzheimer-like neurodegeneration.

  13. Gut Microbiome–Sphingolipid Metabolism–Brain Axis Interactions: Neuroprotective Effects of Amitriptyline as Functional Inhibitor of Acid Sphingomyelinase in a Mouse Model of Tauopathy

    ✓ Peer-reviewed alzhub usefulness score 37 out of 100. Journal of Neuroimmune Pharmacology 2026-01-03 Disease mechanisms

    Tauopathies are neurodegenerative diseases characterized by accumulation of hyperphosphorylated tau protein (P-tau).

  14. Elevated serum inflammasome adaptor protein ASC is associated with white matter hyperintensities in vascular cognitive impairment

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Brain Communications 2026-01-01 Vascular contributions

    Alzheimer's disease (AD) and vascular dementia (VaD) exhibit distinct neuropathological hallmarks, with AD defined by cortical amyloid plaques and neurofibrillary tangles, while VaD arises primarily from cerebrovascular disease (CeVD).

  15. Glymphatic dysfunction associates with regional white matter hyperintensities and plasma amyloid-β burden across the Alzheimer’s disease continuum

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Psychological Medicine 2026-01-01 Vascular contributions

    Plasma Aβ levels and regional WMH burden are associated with glymphatic dysfunction as indicated by reduced ALPS.

  16. Inhibiting Glycogen Synthase Kinase 3 Suppresses TDP-43-Mediated Neurotoxicity in a Caspase-Dependent Manner

    ✓ Peer-reviewed alzhub usefulness score 42 out of 100. Molecular Neurobiology 2026-01-01 Brain tissue and pathology

    We show that TDP-43 activates GSK3 and promotes caspase-dependent cleavage of TDP-43, generating C-terminal fragments.

  17. Microglia-Derived Extracellular Vesicles from Alzheimer’s Disease Patients Carry miRNAs Driving a Neuroinflammatory Response

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Molecular Neurobiology 2026-01-01 Inflammation and the immune system

    Alzheimer's disease (AD) represents the most common cause of dementia and urgently requires sensitive biomarkers and effective therapies.

  18. Small molecule JRMS modulating importin-β1 chaperone activity as a therapeutic strategy reducing TDP-43 pathology

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Neurotherapeutics 2026-01-01 Brain tissue and pathology

    Neuronal cytoplasmic aggregation and nuclear depletion of the TAR DNA-binding protein 43 (TDP-43) is the most characteristic pathology of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), causing toxicity through cytoplasmic gain and nuclear loss of function mechanisms.

  19. LINE-1 retrotransposition in a mouse TDP-43 model of neurodegeneration marks motor cortex neurons for cell-intrinsic and cell non-autonomous programmed cell death

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. PLoS Genetics 2025-12-29 Risk factors

    A key pathological feature of Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD) is the loss of nuclear localization and accumulation of cytoplasmic inclusions of TAR-DNA binding protein 43 (TDP-43).

  20. Pharmacologic reversal of advanced Alzheimer's disease in mice and identification of potential therapeutic nodes in human brain

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Cell reports. Medicine 2025-12-22 Biomarkers

    Alzheimer's disease (AD) is traditionally considered irreversible.

  21. γ-Secretase exosites as targets for substrate-selective lowering of Aβ generation

    ✓ Peer-reviewed alzhub usefulness score 35 out of 100. Structure 2025-12-19 Risk genes beyond APOE

    Intramembrane proteolysis by γ-secretase is critically implicated in Alzheimer disease pathogenesis by processing of its amyloid precursor protein substrate C99 into harmful amyloid-β peptide (Aβ) species.

  22. Deposition of aggregated cystatin C-amyloid-β complexes and reduced cathepsin B activity modulate cerebral amyloid angiopathy pathogenesis

    ✓ Peer-reviewed alzhub usefulness score 32 out of 100. Journal of Neuropathology & Experimental Neurology 2025-12-17 Brain tissue and pathology

    Cystatin C (CST3) colocalizes with amyloid-β (Aβ) around vessels in cerebral amyloid angiopathy (CAA).

  23. Mediterranean Diet, Polyphenols, and Neuroprotection: Mechanistic Insights into Resveratrol and Oleuropein

    ✓ Peer-reviewed alzhub usefulness score 44 out of 100. Nutrients 2025-12-16 Prevention trials

    Epidemiological studies suggest that higher MedDiet adherence is associated with slower cognitive decline, reduced conversion from mild cognitive impairment to Alzheimer’s disease, and better motor and non-motor outcomes in Parkinson’s disease.

  24. Cerebral FURIN deficiency impairs astrocytic lipophagy through ITGAV maturation

    ✓ Peer-reviewed alzhub usefulness score 37 out of 100. Autophagy 2025-12-11 Risk genes beyond APOE

    : ACTB: actin, beta; AD: Alzheimer disease; ADAM10: a disintegrin and metallopeptidase domain 10; ADGGA: acyl diacylglyceryl glucuronide; AHexSIS: acylhexosyl sitosterol; AHexSTS: acylhexosyl stigmasterol; AIF1/IBA1: allograft inflammatory factor 1; APP: amyloid beta precursor protein; ATG5: autophagy related 5; Aβ: amyloid β-protein; BACE1: beta-site APP cleaving enzyme 1; BASulfate: bile acid sulfate; BMP: bismonoacylglycerophosphate; CAR: acylcarnitine; CE: cholesteryl ester; Cer_NS: ceramide non-hydroxyfatty acid-sphingosine; CL: cardiolipin; CMA: chaperone-mediated autophagy; DAPI: 4',6-diamidino-2-phenylindole; DCAE: esterified deoxycholic acid; DEP: differentially expressed protein; DG: diacylglycerol; DGCC: diacylglyceryl-3-O-carboxyhydroxymethylcholine; DLG4/PSD95: discs large MAGUK scaffold protein 4; ECM: extracellular matrix; EtherLPC: ether-linked lysophosphatidylcholine; EtherLPE: ether-linked lysophosphatidylethanolamine; EtherMGDG: ether-linked monogalactosyldiacylglycerol; EtherOxPC: ether-linked oxidized phosphatidylcholine; EtherPC: ether-linked phosphatidylcholine; EtherPE: ether-linked phosphatidylethanolamine; EtherPG: ether-linked phosphatidylglycerol; EtherSMGDG: semino lipid; EtherTG: ether-linked triacylglycerol; FA: fatty acyls; FA: free fatty acid; FAHFA: fatty acid ester of hydroxyl fatty acid; FJC: fluoro-Jade C; GAPDH: glyceraldehyde-3-phosphate dehydrogenase; GDCAE: esterified glycodeoxycholic acid; GFAP: glial fibrillary acidic protein; GL: glycerolipids; GP: glycerophospholipids; HBMP: hemibismonoacylglycerophosphate; HexCer_NS: hexosylceramide non-hydroxyfatty acid-sphingosine; HSPA8/HSC70: heat shock protein 8; IP-MS: immunoprecipitation-mass spectrometry; KEGG: Kyoto Encyclopedia of Genes and Genomes; LAMP1: lysosomal-associated membrane protein 1; LAMP2A: lysosomal-associated membrane protein 2A; LDGCC: lysodiacylglyceryl-3-O-carboxyhydroxymethylcholine; LDs: lipid droplets; LNAPE: N-acyl-lysophosphatidylethanolamine; LNAPS: N-acyl-lysophosphatidylserine; LPA: lysophosphatidic acid; LPC: lyso-phophatidylcholine; LPE: lysophosphatidylethanolamine; LPG: lysophosphatidylglycerol; LPI: lysophosphatidylinositol; LPS: lysophosphatidylserine; MAP1LC3B/LC3B: microtubule-associated protein 1 light chain 3 beta; MGDG: monogalactosyldiacylglycerol; MWM: Morris Water Maze; OA: oleic acid; OFT: Open Field Test; OxPC: oxidized phosphatidylcholine; OxPG: oxidized phosphatidylglycerol; OxPI: oxidized phosphatidylinositol; OxPS: oxidiz

  25. The concentration-dependent protective effects by new generation hypoglycemic agents on delirium, depression, dementia and coma: evidence from a network meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 62 out of 100. Journal of the Royal Society of Medicine 2025-12-08 Clinical safety

    A total of 62 RCTs comprising 200,068 participants were included.

  26. Human TDP-43 overexpression in zebrafish motor neurons triggers MND-like phenotypes through gain-of-function mechanism

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Acta Neuropathologica Communications 2025-12-02 Brain tissue and pathology

    Dysregulation of the TAR DNA-binding protein 43 (TDP-43), including intraneuronal cytoplasmic mislocalisation and aggregation is a feature of multiple neurodegenerative diseases including amyotrophic lateral sclerosis (ALS), frontotemporal lobar dementia (FTLD), limbic-predominant age-related TDP-43 encephalopathy (LATE) and alzheimer’s disease (AD).

  27. Irisin attenuates astrocyte activation and rescues memory in Alzheimer model mice

    ✓ Peer-reviewed alzhub usefulness score 33 out of 100. Alzheimer s & Dementia 2025-12-01 Inflammation and the immune system

    We demonstrate that irisin promotes the expression of brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF), glial cell line-derived neurotrophic factor (GDNF), α5 subunits of integrin receptors and LDH5α, and stimulates transient activation of ERK 1/2 in astrocytes.

  28. Mice with pR927Q and pI712M Erbb4 Mutations Develop Features of Frontotemporal Dementia and ALS

    ✓ Peer-reviewed alzhub usefulness score 33 out of 100. Alzheimer s & Dementia 2025-12-01 Disease mechanisms

    Barnes Maze Acquisition was performed on males (N = 4-5/genotype) after habituation and several days training.

  29. Molecular modeling to simulation: insights into Gaussian QSAR, molecular docking, and DFT for identification of HDAC3 inhibitors for neurocognitive vascular dementia

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Scientific Reports 2025-12-01 Lewy body dementia

    Vascular dementia is the second most common form of dementia.

  30. Monoamine Oxidase‐B (MAO‐B) Identifies Neurotoxic Reactive Astrocytes in Alzheimer's Disease and Related Dementias

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Alzheimer s & Dementia 2025-12-01 Inflammation and the immune system

    Compared to controls, MAO-B immunoreactive area fraction was significantly increased in the frontal cortex and white matter of AD, CBD, and especially PiD and FTLD-TDP, but not PSP.

  31. Presenilin 2 regulates corticosterone-induced autophagic death of adult hippocampal neural stem cells

    ✓ Peer-reviewed alzhub usefulness score 28 out of 100. Animal Cells and Systems 2025-12-01 Risk genes beyond APOE

    Chronic psychological stress is a well-known risk factor for neurodegenerative diseases including Alzheimer disease (AD), yet the underlying mechanisms remain unclear.

  32. Small Molecule Targeting of Chaperone {IP Protein} Prevents and Reverses TDP‐43 Aggregation In‐vitro and In‐vivo

    ✓ Peer-reviewed alzhub usefulness score 33 out of 100. Alzheimer s & Dementia 2025-12-01 Brain tissue and pathology

    Acute and chronic treatment of JRMS reduced TDP-25 aggregation in a dose-dependent manner by ∼75% in cells.

  33. Targeting anaplastic lymphoma kinase (ALK) alleviates synaptic dysfunction associated with C9orf72 haploinsufficiency

    ✓ Peer-reviewed alzhub usefulness score 31 out of 100. Alzheimer s & Dementia 2025-12-01 Disease mechanisms

    Primary cortical neurons with C9orf72 haploinsufficiency exhibit alterations in dendritic branching, indicating disrupted neuronal connectivity.

  34. Structural details of helix-mediated multimerization of the conserved region of TDP-43 C-terminal domain

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Nature Communications 2025-11-26 Brain tissue and pathology

    Pathological inclusions of the C-terminal domain (CTD) of TAR DNA binding protein-43 (TDP-43) are neurodegenerative hallmarks in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia, yet CTD's aggregation propensity complicates structural characterization of native TDP-43.

  35. Activated microglial exosomes enhance α-Synuclein internalization and accelerate neurodegeneration in lewy body dementia

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Journal of Nanobiotechnology 2025-11-25 Inflammation and the immune system

    Lewy body dementia (LBD), which includes Parkinson's disease dementia and dementia with Lewy bodies, is characterized by progressive cognitive decline, α-synuclein (α-Syn) aggregation, and concurrent microglial activation and neuroinflammation.

  36. Acupuncture reduces neuroinflammation and apoptosis, regulates peripheral immunity, and modulates T-cell subset distribution in vascular dementia rats

    ✓ Peer-reviewed alzhub usefulness score 32 out of 100. Chinese Medicine 2025-11-25 Inflammation and the immune system

    Acupuncture ameliorated cognitive impairment in VD rats, reduced hippocampal neuronal damage and apoptosis, downregulated pro-apoptotic proteins (cleaved-caspase 3 and Bax), and upregulated anti-apoptotic Bcl-2.

  37. Inhibition of p38α MAPK increases short-term astrocyte reactivity: the exploratory VIP trial in early Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Journal of neuroinflammation 2025-11-24 TREM2 and immune genetics

    Neuro-inflammation was not reduced between the neflamapimod and placebo groups, and no change was observed in [18F]-DPA-714 PET.

  38. Polystyrene Micro- and Nanoplastic Exposure Triggers an Activation and Stress Response in Human Astrocytes

    ✓ Peer-reviewed alzhub usefulness score 37 out of 100. International Journal of Molecular Sciences 2025-11-21 Inflammation and the immune system

    Recent evidence indicates the presence of micro- and nanoplastics in the human brain, with higher accumulation observed in patients with dementia.

  39. Selective agonism of GPR34 stimulates microglial uptake and clearance of amyloid β fibrils

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Alzheimer s Research & Therapy 2025-11-20 Risk genes beyond APOE

    M1 specifically enhanced uptake of Aβ fibrils through reduction of intracellular cAMP levels, without affecting monomeric or oligomeric Aβ internalization.

  40. The cGAS–STING Pathway in Dementia: An Emerging Mechanism of Neuroinflammation

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Brain Sciences 2025-11-19 Inflammation and the immune system

    Dementia is a growing global health concern in aging societies, leading to a progressive decline in cognitive function that severely impairs daily life.

  41. A modified α-synuclein seed amplification assay in Lewy body dementia using Raman spectroscopy and machine learning analysis

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of Neuroscience Methods 2025-11-15 Digital health tools

    Lewy body dementias (LBD), comprising dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (PDD), are defined by misfolded α-synuclein aggregation.

  42. TDP-43 Regulates Rab4 Levels to Support Synaptic Vesicle Recycling and Neuromuscular Connectivity in Drosophila and Human ALS Models

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. International Journal of Molecular Sciences 2025-11-14 Brain tissue and pathology

    The pathological loss of nuclear TDP-43 is a hallmark of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), leading to extensive alterations in RNA metabolism and a broad number of neuronal transcripts.

  43. The novel sphingolipids cP1P and P1P attenuate neuroinflammation and enhance S1PR1/Akt/mTOR signaling to mitigate cognitive decline in an Alzheimer’s disease mouse model

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Cell Communication and Signaling 2025-11-07 Inflammation and the immune system

    The findings demonstrate that administration of S1P analogs cP1P and P1P at 0.1 mg/kg and 1 mg/kg significantly reduced Aβ burden by inhibiting the amyloidogenic pathway and decreasing hyperphosphorylated tau protein levels in the mouse brain.

  44. Restoration neurite growth by removing the blockage of endosome trafficking in Alzheimer-like mice

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Neurotherapeutics 2025-11-06 Disease mechanisms

    Synaptic loss is strongly associated with cognitive decline in Alzheimer's disease (AD).

  45. Astrocytes upregulate interleukin-15 in response to neuroinflammation during Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 33 out of 100. Journal of Alzheimer s Disease 2025-11-05 Inflammation and the immune system

    Astrocytes are a source of IL-15 in AD, particularly near localized Aβ pathology, and neurons are poised to respond.

  46. Lymphoid gene expression supports neuroprotective microglia function

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Nature 2025-11-05 Laboratory science

    This is primarily a mouse-model study (in amyloid-plaque mouse models such as 5xFAD, with some human tissue validation) identifying a newly recognized, protective state of brain immune cells (microglia) that expresses genes normally associated with the immune system's lymphocytes.

  47. Mitochondrial complex III-derived ROS amplify immunometabolic changes in astrocytes and promote dementia pathology

    ✓ Peer-reviewed alzhub usefulness score 46 out of 100. Nature Metabolism 2025-11-04 Inflammation and the immune system

    Neurodegenerative disorders alter mitochondrial functions, including the production of reactive oxygen species (ROS).

  48. Clemastine ameliorates cognitive deficits in an experimental rat model of chronic cerebral hypoperfusion

    ✓ Peer-reviewed alzhub usefulness score 35 out of 100. Journal of Cerebral Blood Flow & Metabolism 2025-11-03 Disease mechanisms

    Chronic cerebral hypoperfusion (CCH) profoundly affects patient well-being and has been proposed as a risk factor for cognitive impairment and dementia.

  49. Genome‐wide association studies of TDP‐43 proteinopathy and hippocampal sclerosis reveal shared genetic associations with APOE and TMEM106B

    ✓ Peer-reviewed alzhub usefulness score 68 out of 100. Alzheimer s & Dementia 2025-11-01 Genetics

    Two regions achieved genome-wide significance with TDP-43: apolipoprotein E (APOE) and TMEM106B. Three loci reached genome-wide significance with HS: APOE, TMEM106B, and granulin precursor (GRN).

  50. Neurogranin in cerebrospinal fluid as a marker of synaptic dysfunction in hip fracture patients with delirium: a multicentre cross-sectional study

    ✓ Peer-reviewed alzhub usefulness score 44 out of 100. BMJ Open 2025-11-01 Disease mechanisms

    180 patients (46 %) developed delirium and 70% of these had dementia.

From across this tag

10 of the 1,159 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.

All topic tags with their study counts