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leading-causes
109 studies tagged leading-causes, dated 1964-11-01 to 2026-10-29. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Evaluating a primary care pharmacist-led intervention to reduce opioid use for persistent non-cancer pain: the PROMPPT cluster randomised controlled trial protocol 2026-10-29
- Heat-related mortality by comorbidity and cause of death: a time-stratified case-crossover study of 3.7 million deaths in Brazil, 2014–2025 2026-10-22
- Feature harmonization reveals that apparent cross-cohort differences in tau-positivity prediction reflect variable availability and cohort stage structure 2026-10-21
Studies
109 studies carry this tag.
Date range
1964 to 2026
Top journals
- PubMed 7
- medRxiv 6
- Annals of Internal Medicine 5
- Lancet (London, England) 5
- National vital statistics reports : from the Centers for Disease Control and Prevention, National Center for Health Statistics, National Vital Statistics System 5
74 journals in all.
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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The PROMPPT trial will assess whether review by trained clinical pharmacists working in general practices can support safe opioid reduction without compromising pain management and quality of life.
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Because deaths without a given condition differ in cause composition from deaths with it, each condition was also compared with deaths carrying another of the studied conditions: the dementia estimate strengthened to 1.050 (1.036–1.065), and cerebrovascular disease reached 1.018 (1.009–1.027), a smaller but statistically robust positive modification.
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In the primary matched-feature comparison, reference areas under the receiver operating characteristic curve (AUCs) were 0.851 for ADNI tau90, 0.860 for ADNI tau180, and 0.933 for OASIS3 tau180.
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Patients with peripheral artery disease (PAD), chronic limb-threatening ischemia (CLTI), and/or diabetic foot ulcer (DFU) are at increased risk for limb loss and death.
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Seasonally normalized 25(OH)D identifies a reproducible state of systemic vulnerability while reducing exposure misclassification caused by calendar timing of measurement.
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In this setting, selective participation had only a limited effect on prevalence estimates after weighting.
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Among 2144 participants (540 deaths over a median 4.4 years of survivor follow-up; 25% mortality), the seven-marker score plus age and sex achieved an apparent C of 0.74 (optimism-corrected 0.74), versus 0.68 for age and sex alone (Δ ≈ 0.06); the blood panel alone reached C 0.72.
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We examined how often each diagnosed disease appeared on the certificate, its location and selection as the UCD, factors associated with its appearance (logistic regression), disease-specific mortality (multiple decrement life tables), and disease associations (Cause of Death Association Indicator, CDAI).
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Functional decline, as assessed by CGA, was more prominent in patients undergoing hemodialysis than in those not undergoing hemodialysis.
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Among 10,666 patients (mean age 76.6 years; 35% female; 70% White, 21% Black), phenotype distribution was: A, 9.4%; B, 7.1%; C, 50.7%; D, 32.7%.
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16/100
Quantitative measures for tracking functional health have generally been lacking.
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16/100
Previous research has shown patients with mental health issues receive worse quality of diabetes and cardiac care and have poorer outcomes compared with those without mental health issues.
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These findings highlight that extensive long-term utilization of pain management strategies in older adults is associated with increased risks of adverse outcomes, particularly hospitalizations and incident dementia, especially among fit older adults, emphasizing the need for careful monitoring and personalized approaches to pain management in older populations, balancing effective pain control with minimization of potential long-term risks.
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The Ministry of Health, Labor, and Welfare, Japan, launched the Diagnosis Procedure Combination system in 2002.
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Obesity is a significant health crisis affecting more than 123 million adults and children/adolescents in the US.
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52/100
The mean age was 72 years (49-90 years), and 44 (62%) patients were female.
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These three main clusers were confirmed in a testing sample.
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Chronic pain (i.e., pain lasting ≥3 months) is a debilitating condition that affects daily work and life activities for many adults in the United States and has been linked with depression (1), Alzheimer disease and related dementias (2), higher suicide risk (3), and substance use and misuse (4).
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We found higher risks of COVID-19-related outcomes among Black and Hispanic individuals.
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SSAE-3/5 scores correlated with BGTS scores, with high inter-reader intraclass correlation coefficients across all scales.
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Globally, in 2019, there were nearly 10 million deaths and 349 million DALYs due to neurological disorders.
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Atrial fibrillation (AF) is the most common clinical arrhythmia with substantial health and socioeconomic impact on healthcare.1 The number of people affected by this condition was estimated to be 33.5 million in 2010, with an increasing prevalence and incidence over the coming years.2 In 2017, there were 37.6 million [95% confidence interval (CI): 32.5–42.6 million] individuals with AF/atrial flutter globally.3 The estimated number of subjects with AF in 2030 in Europe will be 14–17 million, and the number of new cases of AF per year at 120 000–215 000.4 Atrial fibrillation is independently associated with increased mortality and morbidity from complications such as ischaemic stroke, dementia, and cognitive dysfunction.5 Oral anticoagulation can significantly reduce the risk of stroke, dementia, and death.6 As a part of a holistic or integrated approach to AF care, it is associated with improved outcomes7–9 and is advocated in guidelines.10,11 In many patients, AF can be asymptomatic, and the diagnosis is established after the appearance of a complication typically associated with AF, such as ischaemic stroke/systemic embolic or heart failure.
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66/100
Men, racial and ethnic minority individuals, older adults, and those with language barriers are at increased risk for undertreatment of depression.
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Therefore, respective software was developed in-house.8,9 Segmentation results are then analysed for potential associations with disease risks and to establish reference intervals of organ size and function.10 SHIP is also used as a basis for meta-research with a particular focus on incidental MRI findings and their effects on study participants.11,12 With its large amount of standardized data and the option to internally replicate findings from SHIP-START using data of the independent SHIP-TREND, the project offers good opportunities to apply new bioinformatical tools to mine the data and gain new insights into risk factors and pathomechanisms.
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41/100
Health screening is an important component of health promotion programs, and countries have promoted general health screening targeting the prevention and early management of common chronic diseases.
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LASI is India’s first ageing study and the world’s largest in terms of sample size, and will provide comprehensive longitudinal data for designing policies and programmes targeted toward the overall well-being of the older population.
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Individuals with poor social health were 42 % more likely to develop CVD (p = 0.01) and twice as likely to die from CVD (p = 0.02) over a median 4.5 years follow-up.
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The findings of this large cohort study suggest that system-level measurement and reporting of specific low-value services is feasible, enables cross-system comparisons, and reveals a broad range of low-value care use.
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45/100
An estimated 2.88 million deaths occurred between March and December 2020.
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Specifically, periodontal disease has been associated with diabetes, metabolic syndrome, obesity, eating disorders, liver disease, cardiovascular disease, Alzheimer disease, rheumatoid arthritis, adverse pregnancy outcomes, and cancer.
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This prospective, community-based, nested, case-control study used self-reported data (eg, on demographics, geographical location, health risk factors, and COVID-19 test results, symptoms, and vaccinations) from UK-based, adult (≥18 years) users of the COVID Symptom Study mobile phone app.
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59/100
Illness duration and symptom prevalence, duration, and burden were analysed for children testing positive for SARS-CoV-2 for whom illness duration could be determined, and were assessed overall and for younger (age 5-11 years) and older (age 12-17 years) groups.
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Women with chronic HIV infection (WWH) living in the United States, experience a disproportionately high rate of obesity compared to uninfected populations.
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Our results highlight the need for adequate isolation and protective measures.
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41/100
Neither medically amenable nor behavioral risk factors are uniformly better in Cuba than comparison countries.
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Of 1648 patients with COVID-19 admitted to 38 hospitals, 398 (24.2%) died during hospitalization and 1250 (75.8%) survived.
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We sought to assess risk of COVID-19 among front-line health-care workers compared with the general community and the effect of personal protective equipment (PPE) on risk.
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Of note, dramatic progress has been made in recent years in diabetes research and clinical practice, which includes approval of antidiabetic agents with novel mechanisms of action along with publication of clinical trial results with these drugs, and novel diagnostic and therapeutic devices, such as continuous glucose monitoring (CGM) and sensor augmented pumps (SAP).
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Prior work has shown that the video component significantly contributes to quality and satisfaction of the visit.3 In addition to the technology itself, patients need to know what to expect for their telehealth appointments.
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Total health care spending increased from an estimated $1.4 trillion in 1996 (13.3% of gross domestic product [GDP]; $5259 per person) to an estimated $3.1 trillion in 2016 (17.9% of GDP; $9655 per person); 85.2% of that spending was included in this study.
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n d e n c e Changes in the Place of Death in the United States To the Editor: Where people die is an impor tant determinant of patient and caregiver expe rience.
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As a result, kidney disease has been largely overlooked by health authorities and governments in most countries [9].
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We compared the observed results with expected values estimated based on the Socio-demographic Index (SDI).
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In 2017, the 10 leading causes of death were, in rank order: Diseases of heart; Malignant neoplasms; Accidents (unintentional injuries); Chronic lower respiratory diseases; Cerebrovascular diseases; Alzheimer disease; Diabetes mellitus; Influenza and pneumonia; Nephritis, nephrotic syndrome and nephrosis; and Intentional self-harm (suicide).
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Until recently, intraindividual visit-to-visit variability of cardiovascular risk factors has been dismissed as random fluctuation.
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In this large population-based study, the overall prevalence of Whipple's disease in the USA is 9.8 cases per 1 million people.
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Globally, approximately one in three of all adults suffer from multiple chronic conditions (MCCs).
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Higher all-cause mortality was observed among apparently healthy older adults who received daily aspirin than among those who received placebo and was attributed primarily to cancer-related death.
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Study objective To examine the risks and compare the occurrences of major long-term side effects (sexual dysfunction, bone fractures, diabetes, cardiovascular morbidity, acute myocardial infarction [MI], and dementia) in patients with prostate cancer who received androgen-deprivation therapy (ADT) with those who did not.
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GIM services care for a markedly heterogeneous population but the most common conditions were similar across 7 hospitals.
From across this tag
4 of the 109 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 4. The same 4 appear here every time.
- Healthy centenarians do not exist, but autonomous centenarians do: a population-based study of morbidity among Danish centenarians
- Lower extremity performance in nondisabled older persons as a predictor of subsequent hospitalization
- Robot-assisted laparoscopic prostatectomy versus open radical retropubic prostatectomy: early outcomes from a randomised controlled phase 3 study
- Repeat Hospitalizations Predict Mortality in Patients With Heart Failure