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Home › Research › Topic

Gut, metabolism and diet

1,048 studies in this group. A computer grouped them by what their titles and summaries are about, not by a hand-made list. The name describes most of the group, not every study in it.

Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.

Highest usefulness score first. Studies without a score come last.

  1. Chronic Inflammation as an Immunological Abnormality and Effectiveness of Exercise

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Biomolecules 2019-06-07 Prevention trials

    Reduced levels of physical activity in people's daily lives cause the development of metabolic syndromes or age-related disorders.

  2. Antibiotics, gut microbiota, and Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Journal of neuroinflammation 2019-05-22 Disease mechanisms

    Alzheimer's disease (AD) is a neurodegenerative disease whose various pathophysiological aspects are still being investigated.

  3. Hyperhomocysteinemia as a Risk Factor and Potential Nutraceutical Target for Certain Pathologies

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Frontiers in nutrition 2019-04-24 Biomarkers

    Hyperhomocysteinemia is recognized as a risk factor for several diseases, including cardiovascular and neurological conditions.

  4. Insulin Signaling Impairment in the Brain as a Risk Factor in Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Frontiers in aging neuroscience 2019-04-24 Drug development

    Type 2 diabetes is a risk factor for developing Alzheimer's disease (AD).

  5. Oxidative Stress: A Key Modulator in Neurodegenerative Diseases

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Molecules (Basel, Switzerland) 2019-04-22 Disease mechanisms

    Oxidative stress is proposed as a regulatory element in ageing and various neurological disorders.

  6. The Therapeutic Potential of Apigenin

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. International journal of molecular sciences 2019-03-15 Risk factors

    Several plant bioactive compounds have exhibited functional activities that suggest they could play a remarkable role in preventing a wide range of chronic diseases.

  7. Liraglutide and its Neuroprotective Properties-Focus on Possible Biochemical Mechanisms in Alzheimer's Disease and Cerebral Ischemic Events

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. International journal of molecular sciences 2019-02-28 Drug development

    Liraglutide is a GLP-1 analog (glucagon like peptide-1) used primarily in the treatment of diabetes mellitus type 2 (DM2) and obesity.

  8. Disturbed homocysteine metabolism is associated with cancer

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Experimental & molecular medicine 2019-02-21 Down syndrome and Alzheimer's

    Hyperhomocysteinemia/Homocysteinuria is characterized by an increased level of toxic homocysteine in the plasma.

  9. Early-Stage Alzheimer’s Disease Is Associated with Simultaneous Systemic and Central Nervous System Dysregulation of Insulin-Linked Metabolic Pathways

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Journal of Alzheimer s Disease 2019-02-12 Drug development

    In MCI/AD, both the CSF and serum samples had significantly elevated mean levels of C-peptide and an incretin, and reduced expression of Visfatin, whereas only CSF showed significant reductions in insulin and leptin and only serum had increased glucagon, PAI-1, and ghrelin.

  10. Psychobiotics in mental health, neurodegenerative and neurodevelopmental disorders

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Journal of food and drug analysis 2019-02-10 Disease mechanisms

    Psychobiotics are a group of probiotics that affect the central nervous system (CNS) related functions and behaviors mediated by the gut-brain-axis (GBA) via immune, humoral, neural, and metabolic pathways to improve not only the gastrointestinal (GI) function but also the antidepressant and anxiolytic capacity.

  11. The ketogenic diet influences taxonomic and functional composition of the gut microbiota in children with severe epilepsy

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. NPJ biofilms and microbiomes 2019-01-23 Disease mechanisms

    The gut microbiota has been linked to various neurological disorders via the gut-brain axis.

  12. The Role of Nutrients in Reducing the Risk for Noncommunicable Diseases during Aging

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Nutrients 2019-01-04 Costs and economics

    An increasing aging population worldwide accounts for a growing share of noncommunicable diseases (NCDs) of the overall social and economic burden.

  13. Geniposide-mediated protection against amyloid deposition and behavioral impairment correlates with downregulation of mTOR signaling and enhanced autophagy in a mouse model of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Aging 2019-01-01 Drug development

    Geniposide, an iridoid glycoside extract from the gardenia fruit, is used in traditional Chinese medicine to alleviate symptoms of liver and inflammatory diseases.

  14. Impact of Metabolic Syndrome on Neuroinflammation and the Blood-Brain Barrier

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Frontiers in neuroscience 2018-12-11 Disease mechanisms

    Metabolic syndrome, which includes diabetes and obesity, is one of the most widespread medical conditions.

  15. Oxidative Stress and the Microbiota-Gut-Brain Axis

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Oxidative medicine and cellular longevity 2018-12-09 Disease mechanisms

    The gut-brain axis is increasingly recognized as an important pathway of communication and of physiological regulation, and gut microbiota seems to play a significant role in this mutual relationship.

  16. Gut Microbiota and Their Neuroinflammatory Implications in Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Nutrients 2018-11-14 Disease mechanisms

    The bidirectional communication between the central nervous system (CNS) and the gut microbiota plays a pivotal role in human health.

  17. The Gut Microbiome Alterations and Inflammation-Driven Pathogenesis of Alzheimer's Disease-a Critical Review

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Molecular neurobiology 2018-06-23 Disease mechanisms

    One of the most important scientific discoveries of recent years was the disclosure that the intestinal microflora takes part in bidirectional communication between the gut and the brain.

  18. Abnormal gut microbiota composition contributes to cognitive dysfunction in SAMP8 mice

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Aging 2018-06-10 Disease mechanisms

    Alzheimer's disease is characterized by cognitive dysfunction and aging is an important predisposing factor; however, the pathological and therapeutic mechanisms are not fully understood.

  19. Interplay among gut microbiota, intestinal mucosal barrier and enteric neuro-immune system: a common path to neurodegenerative diseases?

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Acta neuropathologica 2018-05-24 Disease mechanisms

    Neurological diseases, such as Parkinson's disease, Alzheimer's disease, amyotrophic lateral sclerosis (ALS) and multiple sclerosis, are often associated with functional gastrointestinal disorders.

  20. Ketogenic diet enhances neurovascular function with altered gut microbiome in young healthy mice

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Scientific reports 2018-04-27 Disease mechanisms

    Neurovascular integrity, including cerebral blood flow (CBF) and blood-brain barrier (BBB) function, plays a major role in determining cognitive capability.

  21. Galantamine improves cognition, hippocampal inflammation, and synaptic plasticity impairments induced by lipopolysaccharide in mice

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Journal of neuroinflammation 2018-04-18 Biomarkers

    These findings indicate that galantamine could be a promising treatment to improve endotoxin-induced cognitive decline and neuroinflammation in neurodegenerative diseases.

  22. The diabetes drug liraglutide reverses cognitive impairment in mice and attenuates insulin receptor and synaptic pathology in a non-human primate model of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. The Journal of pathology 2018-04-02 Drug development

    Alzheimer's disease (AD) is a devastating neurological disorder that still lacks an effective treatment, and this has stimulated an intense pursuit of disease-modifying therapeutics.

  23. Mitochondrial dysfunction in down syndrome: molecular mechanisms and therapeutic targets

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Molecular medicine (Cambridge, Mass.) 2018-03-15 Down syndrome and Alzheimer's

    Trisomy of chromosome 21 (TS21) is the most common autosomal aneuploidy compatible with postnatal survival with a prevalence of 1 in 700 newborns.

  24. Role of Plant Derived Alkaloids and Their Mechanism in Neurodegenerative Disorders

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. International journal of biological sciences 2018-03-09 Treatments

    Neurodegenerative diseases are conventionally demarcated as disorders with selective loss of neurons.

  25. SLAB51 Probiotic Formulation Activates SIRT1 Pathway Promoting Antioxidant and Neuroprotective Effects in an AD Mouse Model

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Molecular neurobiology 2018-02-28 Disease mechanisms

    The gut-brain axis is a bidirectional communication network functionally linking the gut and the central nervous system (CNS).

From across this topic

10 of the 1,048 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.

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