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51/100

✓ Peer-reviewed alzhub usefulness score 51 out of 100. Lewy body dementia

Topic: Risk, prevention and care in population studies

There were 56.9 million people worldwide living with dementia in 2021, according to the Global Burden of Disease study, and this number is projected to exceed 137 million by 2050. Vascular dementia (VaD) is the second leading cause of dementia. While high-quality global epidemiological data on VaD remain limited, population-based studies with autopsy confirmation allow an approximate estimation. These show that pure VaD represents approximately 15% of all dementia cases, with mixed vascular and degenerative dementia accounting for an additional 16%. According to these estimates, approximately 8.5 million people worldwide suffer from pure VaD, and 9.1 million from mixed dementia. Under the assumption that existing proportional rates remain constant, the global burden of total VaD (i.e. pure VaD and mixed dementia) will reach 42.7 million cases by 2050. However, the impact of cerebrovascular disease is likely to be even greater. Increasing evidence demonstrates that vascular pathology commonly coexists with Alzheimer's and other neurodegenerative pathologies, increasing the risk that these neurodegenerative pathologies cause clinical dementia. Despite the importance of VaD, it remains underrecognized and underresearched compared to other forms of dementia. This fact sheet highlights the urgent need for improved recognition, standardized diagnostic approaches, and enhanced preventive strategies for this highly prevalent yet underrecognized cause of dementia. The factsheet has been reviewed and approved by the World Stroke Organization (WSO) executive.

Key findings

Despite the importance of VaD, it remains underrecognized and underresearched compared to other forms of dementia.

Why it matters

Vascular dementia remains underrecognized and underresearched compared to other forms of dementia, despite being the second leading cause. This fact sheet highlights the urgent need for improved recognition, standardized diagnostic approaches, and enhanced prevention.

Study details

Evidence strengthLow

How this study scored 51/100

Published in a peer-reviewed journal. Scored zero for study design, sample size, effect reported, studied in people and randomised / blinded because the record does not state it.

Component	Points	Why
Journal tier	7 / 10	Tier 3 — peer-reviewed journal (International Journal of Stroke)
Journal's citation record	1 / 4	International Journal of Stroke: journal h-index 133 (OpenAlex, 2026-10-29)
Study design	0 / 12	No study design recorded — scores zero, not guessed (not stated in the record — scored 0)
Strength of evidence	1 / 5	Rated “low” in our summary
Peer-review validation	10 / 10	Peer-reviewed. Published as an article in a named peer-reviewed journal.
How recent	5 / 5	2026 — within 1 year(s) of the newest study here
Sample size	0 / 4	Participant count not stated — scores zero (not stated in the record — scored 0)
Effect reported	0 / 3	No effect size reported — scores zero (not stated in the record — scored 0)
Studied in people	0 / 3	Not stated whether this was studied in people — scores zero (not stated in the record — scored 0)
Randomised / blinded	0 / 2	No randomisation or blinding stated — scores zero (not stated in the record — scored 0)
Times cited	3 / 7	Cited 18 times (OpenAlex, 2026-10-10)
Citations per year	3 / 5	9.0 citations a year over 2 year(s) since 2026
Impact for its field and year	6 / 6	Cited 85.4× the average for papers of its field and year (OpenAlex FWCI)
Cited by studies here	1 / 6	Cited by 1 other studies in this library
Still being cited	2 / 4	Cited 18 times in 2024–2026 (2026 still in progress; OpenAlex)
Senior author's track record	4 / 4	Last-listed author Hugh Stephen Markus: h-index 137 (OpenAlex, whole career)
Institution's track record	2 / 3	University of Cambridge: institution h-index 1,973 (OpenAlex)
Multi-centre collaboration	2 / 3	OpenAlex lists 4 institution(s) in 3 countries
Indexed in PubMed	2 / 2	Indexed in PubMed (PMID 41479247)
Free to read	2 / 2	Free to read
Total	51 / 100	—

What each of these 20 components measures, and what this score is not →

Read the original

Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).

Cite this study APA, Vancouver, BibTeX · download .bib or .ris

Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. Check the citation against the original before you use it.

APA 7th

Cai, Y., Mok, V., & Markus, H. S. (2026). Vascular dementia: World Stroke Organization fact sheet 2026. International Journal of Stroke. https://doi.org/10.1177/17474930251404243

Vancouver

Cai Y, Mok V, Markus HS. Vascular dementia: World Stroke Organization fact sheet 2026. International Journal of Stroke. 2026. doi:10.1177/17474930251404243. PMID: 41479247.

BibTeX

@article{cai2026-41479247,
  author  = {Cai, Yuan and Mok, Vincent and Markus, Hugh Stephen},
  title   = {{Vascular dementia: World Stroke Organization fact sheet 2026}},
  journal = {International Journal of Stroke},
  year    = {2026},
  doi     = {10.1177/17474930251404243},
  pmid    = {41479247},
  url     = {https://doi.org/10.1177/17474930251404243}
}

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