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Using the ascertain dementia eight-item questionnaire to identify at-risk older surgical patients
Ellene Yan, Yasmin Alhamdah, Nina Butris, Paras Kapoor, David He, Leif Erik Lovblom, Maria Carmela Tartaglia, David F. Tang‐Wai et al.. Journal of Clinical Anesthesia, 2026-06-04
Topic: Risk, prevention and care in population studies
Of 689 participants, CI was associated with delirium (adjusted odds ratio [aOR]: 3.64, 95% CI: 1.31, 9.49, P-value = 0.009), 90-day complications (aOR: 2.26, 95% CI: 1.14, 4.28, P-value = 0.015), and 90-day composite adverse outcomes (aOR: 2.03, 95% CI: 1.03, 3.81, P-value = 0.033). Importantly, the AD8 item on repetition was associated with delirium (aOR: 6.11, 95% CI: 2.05, 16.48, P-value = 0.004), 30-day complications (aOR: 2.53, 95% CI: 1.43, 4.45, P-value = 0.004), and 30-day composite adverse outcomes (aOR: 2.52, 95% CI: 1.44, 4.46, P-value = 0.004). Also, memory-related problems showed higher odds of delirium (aOR: 5.11, 95% CI: 1.90, 13.32, P-value = 0.007), 30-day all-cause complications (aOR: 1.77, 95% CI: 1.11, 2.79, P-value = 0.044), and 30-day composite adverse outcomes (aOR: 2.02, 95% CI: 1.30, 3.14, P-value = 0.008). A positive AD8 screen identified older surgical patients at risk of delirium and 90-day complications. Of all AD8 items, repetition was associated with the greatest number of adverse outcomes within 30 days postoperatively, highlighting its potential preoperative utility.
Key findings
- Of 689 participants, CI was associated with delirium (adjusted odds ratio [aOR]: 3.64, 95% CI: 1.31, 9.49, P-value = 0.009), 90-day complications (aOR: 2.26, 95% CI: 1.14, 4.28, P-value = 0.015), and 90-day composite adverse outcomes (aOR: 2.03, 95% CI: 1.03, 3.81, P-value = 0.033).
- Importantly, the AD8 item on repetition was associated with delirium (aOR: 6.11, 95% CI: 2.05, 16.48, P-value = 0.004), 30-day complications (aOR: 2.53, 95% CI: 1.43, 4.45, P-value = 0.004), and 30-day composite adverse outcomes (aOR: 2.52, 95% CI: 1.44, 4.46, P-value = 0.004).
- Also, memory-related problems showed higher odds of delirium (aOR: 5.11, 95% CI: 1.90, 13.32, P-value = 0.007), 30-day all-cause complications (aOR: 1.77, 95% CI: 1.11, 2.79, P-value = 0.044), and 30-day composite adverse outcomes (aOR: 2.02, 95% CI: 1.30, 3.14, P-value = 0.008).
- A positive AD8 screen identified older surgical patients at risk of delirium and 90-day complications.
- Of all AD8 items, repetition was associated with the greatest number of adverse outcomes within 30 days postoperatively, highlighting its potential preoperative utility.
Why it matters
In 689 older surgical patients, a positive AD8 dementia screen was associated with higher odds of delirium and complications after surgery, with the repetition item showing the strongest links. This supports using the AD8 before surgery to flag at-risk patients, but it does not test any treatment or cure.
Study details
- Study designcohort study
- Participants689
- Effect sizeaOR: 2.26; aOR: 2.03; aOR: 6.11
- Evidence strengthModerate
How this study scored 60/100
Published in a peer-reviewed journal, and it is a cohort study following people over time. Scored zero for randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Journal of Clinical Anesthesia) |
| Journal's citation record | 1 / 4 | Journal of Clinical Anesthesia: journal h-index 114 (OpenAlex, 2026-10-29) |
| Study design | 7 / 12 | A cohort study following people over time |
| Strength of evidence | 3 / 5 | Rated “moderate” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 5 / 5 | 2026 — within 1 year(s) of the newest study here |
| Sample size | 2 / 4 | 689 participants |
| Effect reported | 3 / 3 | Effect reported with a statistic (interval, p-value, ratio or similar) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 1 / 7 | Cited 3 times (OpenAlex, 2026-10-10) |
| Citations per year | 1 / 5 | 1.5 citations a year over 2 year(s) since 2026 |
| Impact for its field and year | 4 / 6 | Cited 16.9× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 1 / 4 | Cited 3 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 4 / 4 | Last-listed author Frances F. Chung: h-index 112 (OpenAlex, whole career) |
| Institution's track record | 2 / 3 | University of Toronto: institution h-index 1,923 (OpenAlex) |
| Multi-centre collaboration | 2 / 3 | OpenAlex lists 6 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 42242113) |
| Free to read | 2 / 2 | Free to read |
| Total | 60 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
- DOI: 10.1016/j.jclinane.2026.112256
- PubMed: 42242113
- Original source →
- Free full text: Journal of Clinical Anesthesia →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record's author list ends in “et al.”, so not every author is named. Check the citation against the original before you use it.
APA 7th
Yan, E., Alhamdah, Y., Butris, N., Kapoor, P., He, D., Lovblom, L. E., et al. (2026). Using the ascertain dementia eight-item questionnaire to identify at-risk older surgical patients. Journal of Clinical Anesthesia. https://doi.org/10.1016/j.jclinane.2026.112256
Vancouver
Yan E, Alhamdah Y, Butris N, Kapoor P, He D, Lovblom LE, et al. Using the ascertain dementia eight-item questionnaire to identify at-risk older surgical patients. Journal of Clinical Anesthesia. 2026. doi:10.1016/j.jclinane.2026.112256. PMID: 42242113.
BibTeX
@article{yan2026-42242113,
author = {Yan, Ellene and Alhamdah, Yasmin and Butris, Nina and Kapoor, Paras and He, David and Lovblom, Leif Erik and Tartaglia, Maria Carmela and Tang‐Wai, David F. and others},
title = {{Using the ascertain dementia eight-item questionnaire to identify at-risk older surgical patients}},
journal = {Journal of Clinical Anesthesia},
year = {2026},
doi = {10.1016/j.jclinane.2026.112256},
pmid = {42242113},
url = {https://doi.org/10.1016/j.jclinane.2026.112256}
}
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