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42/100

✓ Peer-reviewed alzhub usefulness score 42 out of 100. Long-term cohort studies

Topic: Risk, prevention and care in population studies

Introduction Poor gait has recently emerged as a potential prodromal feature of cognitive decline and dementia. We assessed to what extent various aspects of poor gait are independently associated with cognitive decline and incident dementia. Methods We leveraged detailed quantitative gait (GAITRite™) and cognitive assessments in 4258 dementia-free participants (median age 67 years, 55% women) of the population-based Rotterdam Study (baseline 2009-2013).

Cite this study APA, Vancouver, BibTeX · download .bib or .ris

APA 7th

Darweesh, S. K. L., Licher, S., Wolters, F. J., Koudstaal, P. J., Ikram, M. K., & Ikram, M. A. (2019). Quantitative gait, cognitive decline, and incident dementia: The Rotterdam Study. Alzheimer's & dementia : the journal of the Alzheimer's Association. https://doi.org/10.1016/j.jalz.2019.03.013

Vancouver

Darweesh SKL, Licher S, Wolters FJ, Koudstaal PJ, Ikram MK, Ikram MA. Quantitative gait, cognitive decline, and incident dementia: The Rotterdam Study. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2019. doi:10.1016/j.jalz.2019.03.013. PMID: 31515066.

BibTeX

@article{darweesh2019-31515066,
  author  = {Darweesh, S. K. L. and Licher, S. and Wolters, F. J. and Koudstaal, P. J. and Ikram, M. K. and Ikram, M. A.},
  title   = {{Quantitative gait, cognitive decline, and incident dementia: The Rotterdam Study}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2019},
  doi     = {10.1016/j.jalz.2019.03.013},
  pmid    = {31515066},
  url     = {https://doi.org/10.1016/j.jalz.2019.03.013}
}

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Key findings

We assessed to what extent various aspects of poor gait are independently associated with cognitive decline and incident dementia.
Methods We leveraged detailed quantitative gait (GAITRite™) and cognitive assessments in 4258 dementia-free participants (median age 67 years, 55% women) of the population-based Rotterdam Study (baseline 2009-2013).
We summarized 30 gait parameters into seven mutually independent gait domains and a Global Gait score.
Participants underwent follow-up cognitive assessments between 2014 and 2016 and were followed up for incident dementia until 2016 (median 4 years).

Why it matters

This study found that certain aspects of walking (gait) were linked to cognitive decline and dementia in a large group of older adults without dementia at the start. It suggests that measuring how someone walks might help identify people at risk, but it does not show that changing gait prevents or treats dementia.

Study details

Evidence strengthLow

How this study scored 42/100

Published in a leading specialty journal. Scored zero for study design, sample size, effect reported, studied in people and randomised / blinded because the record does not state it. We have no data on senior author's track record, so that was left out: it earned 40 of the 96 points we could judge it on, which is 42 out of 100.

Component	Points	Why
Journal tier	9 / 10	Tier 2 — leading specialty journal (Alzheimer's & dementia : the journal of the Alzheimer's Association)
Journal's citation record	2 / 4	Alzheimer s & Dementia: journal h-index 228 (OpenAlex, 2026-10-29)
Study design	0 / 12	No study design recorded — scores zero, not guessed (not stated in the record — scored 0)
Strength of evidence	1 / 5	Rated “low” in our summary
Peer-review validation	10 / 10	Peer-reviewed. Published as an article in a named peer-reviewed journal.
How recent	2 / 5	2019 — within 10 year(s) of the newest study here
Sample size	0 / 4	Participant count not stated — scores zero (not stated in the record — scored 0)
Effect reported	0 / 3	No effect size reported — scores zero (not stated in the record — scored 0)
Studied in people	0 / 3	Not stated whether this was studied in people — scores zero (not stated in the record — scored 0)
Randomised / blinded	0 / 2	No randomisation or blinding stated — scores zero (not stated in the record — scored 0)
Times cited	4 / 7	Cited 64 times (OpenAlex, 2026-10-10)
Citations per year	2 / 5	7.1 citations a year over 9 year(s) since 2019
Impact for its field and year	3 / 6	Cited 3.7× the average for papers of its field and year (OpenAlex FWCI)
Cited by studies here	2 / 6	Cited by 3 other studies in this library
Still being cited	2 / 4	Cited 39 times in 2024–2026 (2026 still in progress; OpenAlex)
Senior author's track record	— / 4	Senior author's record not available — left out of this score
Institution's track record	1 / 3	Erasmus MC: institution h-index 1,321 (OpenAlex)
Multi-centre collaboration	0 / 3	OpenAlex lists 1 institution(s) in 1 country — scores zero (affiliation lists can be incomplete)
Indexed in PubMed	2 / 2	Indexed in PubMed (PMID 31515066)
Free to read	0 / 2	Behind a paywall — scores zero
Points	40 / 96	Scored on 19 of 20 parts. We have no data for the rest, so they are left out: 40 of the 96 points we could judge it on is 42 out of 100.
Total	42 / 100	—

What each of these 20 components measures, and what this score is not →

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