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Prevalence and Misperception: Exploring the Gap Between Objective and Subjective Assessment of Sleep Apnea in a Population at Increased Risk for Dementia
Miren Altuna, Maite García‐Sebastián, Mirian Ecay‐Torres, Jon Saldias, Marta Cañada, Ainara Estanga, Carolina López, Mikel Tainta et al.. Journal of Clinical Medicine, 2025-04-10
Topic: Risk, prevention and care in population studies
Among 322 participants (48.8% women; mean age 71.4 ± 6.4 years), moderate-to-severe OSA (apnea–hypopnea index [AHI] ≥ 15) was identified in 48.49%, despite the absence of prior diagnoses. Subjective screening tools frequently underestimated OSA severity compared to objective assessments. While no significant sex-based differences were noted, higher AHI values correlated strongly with increased body mass index and elevated dementia risk scores. A marked discrepancy between subjective and objective sleep measurements complicates the accurate diagnosis and management of most sleep disorders, including OSA. Sleep disorders remain significantly underdiagnosed in individuals at increased risk for dementia. Integrating wearable technologies and structured tools such as sleep diaries into routine assessments can enhance diagnostic precision, enabling timely interventions for these modifiable risk factors of dementia.
Key findings
- Among 322 participants (48.8% women; mean age 71.4 ± 6.4 years), moderate-to-severe OSA (apnea–hypopnea index [AHI] ≥ 15) was identified in 48.49%, despite the absence of prior diagnoses.
- Subjective screening tools frequently underestimated OSA severity compared to objective assessments.
- While no significant sex-based differences were noted, higher AHI values correlated strongly with increased body mass index and elevated dementia risk scores.
- A marked discrepancy between subjective and objective sleep measurements complicates the accurate diagnosis and management of most sleep disorders, including OSA.
- Sleep disorders remain significantly underdiagnosed in individuals at increased risk for dementia.
Why it matters
In a group at increased risk for dementia, moderate-to-severe sleep apnea was common but often undiagnosed, and subjective screening tools underestimated its severity. This suggests that better objective assessment of sleep apnea could help identify and treat a modifiable risk factor for dementia.
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Study details
- Study designcross-sectional
- Participants322
- Effect size48.8%; 48.49%
- Evidence strengthLow
How this study scored 49/100
Published in a peer-reviewed journal, and it is a snapshot of people at one point in time. Scored zero for randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Journal of Clinical Medicine) |
| Journal's citation record | 2 / 4 | Journal of Clinical Medicine: journal h-index 188 (OpenAlex, 2026-10-29) |
| Study design | 4 / 12 | A snapshot of people at one point in time |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 4 / 5 | 2025 — within 3 year(s) of the newest study here |
| Sample size | 2 / 4 | 322 participants |
| Effect reported | 2 / 3 | Effect reported as a number, without an interval or test |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 2 / 7 | Cited 6 times (OpenAlex, 2026-10-10) |
| Citations per year | 1 / 5 | 2.0 citations a year over 3 year(s) since 2025 |
| Impact for its field and year | 3 / 6 | Cited 3.3× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 1 / 4 | Cited 6 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 2 / 4 | Last-listed author Pablo Martínez‐Lage: h-index 45 (OpenAlex, whole career) |
| Institution's track record | 0 / 3 | Osakidetza: institution h-index 124 (OpenAlex) |
| Multi-centre collaboration | 1 / 3 | OpenAlex lists 2 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 40283437) |
| Free to read | 2 / 2 | Free to read |
| Total | 49 / 100 | — |
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Read the original
- DOI: 10.3390/jcm14082607
- PubMed: 40283437
- Original source →
- Free full text: Journal of Clinical Medicine →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record's author list ends in “et al.”, so not every author is named. Check the citation against the original before you use it.
APA 7th
Altuna, M., García‐Sebastián, M., Ecay‐Torres, M., Saldias, J., Cañada, M., Estanga, A., et al. (2025). Prevalence and Misperception: Exploring the Gap Between Objective and Subjective Assessment of Sleep Apnea in a Population at Increased Risk for Dementia. Journal of Clinical Medicine. https://doi.org/10.3390/jcm14082607
Vancouver
Altuna M, García‐Sebastián M, Ecay‐Torres M, Saldias J, Cañada M, Estanga A, et al. Prevalence and Misperception: Exploring the Gap Between Objective and Subjective Assessment of Sleep Apnea in a Population at Increased Risk for Dementia. Journal of Clinical Medicine. 2025. doi:10.3390/jcm14082607. PMID: 40283437.
BibTeX
@article{altuna2025-40283437,
author = {Altuna, Miren and García‐Sebastián, Maite and Ecay‐Torres, Mirian and Saldias, Jon and Cañada, Marta and Estanga, Ainara and López, Carolina and Tainta, Mikel and others},
title = {{Prevalence and Misperception: Exploring the Gap Between Objective and Subjective Assessment of Sleep Apnea in a Population at Increased Risk for Dementia}},
journal = {Journal of Clinical Medicine},
year = {2025},
doi = {10.3390/jcm14082607},
pmid = {40283437},
url = {https://doi.org/10.3390/jcm14082607}
}
Studies this one cites
Referenced by this study and also in the alzhub library, so you can read them here.