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Financial Incentives to Increase Diversity of Older Participants in a Memory Concerns Registry: A Randomized Clinical Trial
Jacobson M, Molina-Henry D, Chang TY, Jimenez-Maggiora GA, Pramanik R, Shah SB, Aisen PS.. JAMA health forum, 2025-08-01
Topic: Risk, prevention and care in population studies
Results Of 44 844 patients invited to the APT Webstudy, the mean (SD) age was 64.7 (10.1) years, 25 447 (56.8%) were women, 25 044 (55.8%) had Medicaid insurance, 11 347 (25.3%) were Hispanic/Latino, 9526 (21.2%) were non-Hispanic Asian, 6044 (13.5%) were non-Hispanic Black, and 12 109 (27%) were non-Hispanic White. Secondary heterogeneity analyses indicated that patients of White race (adjusted OR, 1.61; 95% CI, 1.15-2.25; P = .006) and male sex (adjusted OR, 2.40; 95% CI, 1.55-3.75; P Conclusions and relevance In this randomized clinical trial, relative to message invitations, invitations with guaranteed, small financial incentives but not lottery incentives increased enrollment of economically but not necessarily racially or ethnically diverse participants to a study that aimed to increase enrollment in clinical studies.
Key findings
- Results Of 44 844 patients invited to the APT Webstudy, the mean (SD) age was 64.7 (10.1) years, 25 447 (56.8%) were women, 25 044 (55.8%) had Medicaid insurance, 11 347 (25.3%) were Hispanic/Latino, 9526 (21.2%) were non-Hispanic Asian, 6044 (13.5%) were non-Hispanic Black, and 12 109 (27%) were non-Hispanic White.
- Secondary heterogeneity analyses indicated that patients of White race (adjusted OR, 1.61; 95% CI, 1.15-2.25; P = .006) and male sex (adjusted OR, 2.40; 95% CI, 1.55-3.75; P < .001) were most responsive to the small $25 incentive relative to the message-only arm.
Why it matters
Offering small guaranteed payments, but not lottery-style prizes, increased enrollment of people with Medicaid insurance into a memory concerns registry. However, it did not clearly increase enrollment of racially or ethnically diverse participants.
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Study details
- Participants844
- Effect size56.8%; 55.8%; 25.3%
- Evidence strengthHigh
How this study scored 61/100
Published in a peer-reviewed journal, and it is a randomised controlled trial.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (JAMA health forum) |
| Journal's citation record | 0 / 4 | JAMA Health Forum: journal h-index 60 (OpenAlex, 2026-10-29) |
| Study design | 11 / 12 | A randomised controlled trial (from PubMed type “Randomized Controlled Trial”) |
| Strength of evidence | 5 / 5 | Rated “high” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 4 / 5 | 2025 — within 3 year(s) of the newest study here |
| Sample size | 2 / 4 | 844 participants |
| Effect reported | 2 / 3 | Effect reported as a number, without an interval or test |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 1 / 2 | Randomised (as stated in the record) |
| Times cited | 1 / 7 | Cited 3 times (OpenAlex, 2026-10-10) |
| Citations per year | 1 / 5 | 1.0 citations a year over 3 year(s) since 2025 |
| Impact for its field and year | 2 / 6 | Cited 2.5× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 1 / 4 | Cited 3 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 4 / 4 | Last-listed author Paul S. S. Aisen: h-index 100 (OpenAlex, whole career) |
| Institution's track record | 2 / 3 | University of Southern California: institution h-index 1,521 (OpenAlex) |
| Multi-centre collaboration | 1 / 3 | OpenAlex lists 2 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 40844772) |
| Free to read | 2 / 2 | Free to read |
| Total | 61 / 100 | — |
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Read the original
- DOI: 10.1001/jamahealthforum.2025.2273
- PubMed: 40844772
- Original source →
- Free full text: JAMA Health Forum →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record names 7 authors; APA and Vancouver show the first six, BibTeX and the downloads carry all of them. Check the citation against the original before you use it.
APA 7th
Jacobson, M., Molina-Henry, D., Chang, T. Y., Jimenez-Maggiora, G. A., Pramanik, R., Shah, S. B., et al. (2025). Financial Incentives to Increase Diversity of Older Participants in a Memory Concerns Registry: A Randomized Clinical Trial. JAMA health forum. https://doi.org/10.1001/jamahealthforum.2025.2273
Vancouver
Jacobson M, Molina-Henry D, Chang TY, Jimenez-Maggiora GA, Pramanik R, Shah SB, et al. Financial Incentives to Increase Diversity of Older Participants in a Memory Concerns Registry: A Randomized Clinical Trial. JAMA health forum. 2025. doi:10.1001/jamahealthforum.2025.2273. PMID: 40844772.
BibTeX
@article{jacobson2025-40844772,
author = {Jacobson, M. and Molina-Henry, D. and Chang, T. Y. and Jimenez-Maggiora, G. A. and Pramanik, R. and Shah, S. B. and Aisen, P. S.},
title = {{Financial Incentives to Increase Diversity of Older Participants in a Memory Concerns Registry: A Randomized Clinical Trial}},
journal = {JAMA health forum},
year = {2025},
doi = {10.1001/jamahealthforum.2025.2273},
pmid = {40844772},
url = {https://doi.org/10.1001/jamahealthforum.2025.2273}
}
Studies this one cites
Referenced by this study and also in the alzhub library, so you can read them here.