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Diagnostic efficacy of computerized spectral versus visual EEG analysis in elderly normal, demented and depressed subjects
Brenner RP, Reynolds CF, Ulrich RF.. Electroencephalography and clinical neurophysiology, 1988-02-01
Topic: Risk, prevention and care in population studies
Computerized spectral and visual EEG analyses were performed in 35 patients with Alzheimer's disease (AD) and compared to 23 patients with major depression and to 61 healthy elderly controls. In particular, we were interested in the diagnostic efficacy of these two techniques in the identification of cases of AD with only mild cognitive impairment (as measured by the Folstein Mini-Mental State score). For the computer analyzed data, in differentiating AD patients from controls, the spectral pooled parasagittal mean frequency was used. In comparing AD patients to depressed subjects, a combined parasagittal delta and theta spectral score was employed. Visual analysis criteria were based on the severity of generalized EEG abnormalities (with or without focal features). We found that spectral analysis afforded only modest advantages over visual EEG analysis in differentiating AD patients from elderly controls as well as from those with major depression. Since the degree of spectral and visual EEG abnormalities correlated with the severity of dementia, both tests more often correctly classified those AD patients with lower Folstein scores. Also, both tests identified primarily the same patients. We did not find the computer to be more sensitive than the eye in the identification of AD patients with mild impairment. However, computerized spectral data was derived from only 4 channels, while 16 channels and a longer recording time were used for visual analysis. In addition, some areas which have been reported to show EEG abnormalities in AD were not included in the computerized data.
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APA 7th
Brenner, R. P., Reynolds, C. F., & Ulrich, R. F. (1988). Diagnostic efficacy of computerized spectral versus visual EEG analysis in elderly normal, demented and depressed subjects. Electroencephalography and clinical neurophysiology. https://doi.org/10.1016/0013-4694(88)90206-4
Vancouver
Brenner RP, Reynolds CF, Ulrich RF. Diagnostic efficacy of computerized spectral versus visual EEG analysis in elderly normal, demented and depressed subjects. Electroencephalography and clinical neurophysiology. 1988. doi:10.1016/0013-4694(88)90206-4. PMID: 2446830.
BibTeX
@article{brenner1988-2446830,
author = {Brenner, R. P. and Reynolds, C. F. and Ulrich, R. F.},
title = {{Diagnostic efficacy of computerized spectral versus visual EEG analysis in elderly normal, demented and depressed subjects}},
journal = {Electroencephalography and clinical neurophysiology},
year = {1988},
doi = {10.1016/0013-4694(88)90206-4},
pmid = {2446830},
url = {https://doi.org/10.1016/0013-4694(88)90206-4}
}
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Key findings
- Computerized spectral and visual EEG analyses were performed in 35 patients with Alzheimer's disease (AD) and compared to 23 patients with major depression and to 61 healthy elderly controls.
- We found that spectral analysis afforded only modest advantages over visual EEG analysis in differentiating AD patients from elderly controls as well as from those with major depression.
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Study details
- Participants35
- Evidence strengthLow
How this study scored 43/100
Published in a peer-reviewed journal. Scored zero for study design, effect reported and randomised / blinded because the record does not state it. We have no data on journal's citation record, times cited, citations per year, impact for its field and year, cited by studies here, still being cited, senior author's track record, institution's track record and multi-centre collaboration, so those were left out: it earned 25 of the 58 points we could judge it on, which is 43 out of 100.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Electroencephalography and clinical neurophysiology) |
| Journal's citation record | — / 4 | No journal record from OpenAlex — left out of this score |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 1 / 5 | 1988 — older than 20 years, still counted |
| Sample size | 1 / 4 | 35 participants |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | — / 7 | No citation count (not found in OpenAlex) — left out of this score |
| Citations per year | — / 5 | No citation count or no year — left out of this score |
| Impact for its field and year | — / 6 | No field-weighted citation impact (OpenAlex has none yet) — left out of this score |
| Cited by studies here | — / 6 | Not yet checked against this library's citation graph — left out of this score |
| Still being cited | — / 4 | No yearly citation counts — left out of this score |
| Senior author's track record | — / 4 | Senior author's record not available — left out of this score |
| Institution's track record | — / 3 | No institution listed in OpenAlex — left out of this score |
| Multi-centre collaboration | — / 3 | Institutions not listed — left out of this score |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 2446830) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Points | 25 / 58 | Scored on 11 of 20 parts. We have no data for the rest, so they are left out: 25 of the 58 points we could judge it on is 43 out of 100. |
| Total | 43 / 100 | — |
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