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40/100

✓ Peer-reviewed alzhub usefulness score 40 out of 100. Getting a diagnosis

Topic: Risk, prevention and care in population studies

Plain-language summary

Probable sarcopenia subjects with dementia were older (68.5(7.8) years old) as compared to those without dementia (66.0(6.0) years old). Among the probable sarcopenia, 66.1% of the subjects with dementia had hypertension, while 64.3% of the sarcopenia subjects had hypertension. Fat mass was significantly higher among dementia subjects with probable sarcopenia (33.0(6.5) %) as compared to non-dementia subjects (30.4(6.8) %). Multivariate analysis revealed that hypertension (OR: 4.049; 95% CI: 1.510; 10.855, p = 0.005) was the only factor associated with dementia risk among older adults with probable sarcopenia and sarcopenia. Hypertension is the only factors associated with risk of dementia after adjusting for potential confounders among older adults with probable sarcopenia and sarcopenia. Good control of blood pressure is essential among sarcopenia patients for lowering risk of dementia. Well-designed clinical trials are essential to investigate optimizing blood pressure level to reduce risk of dementia among patients with sarcopenia and probable sarcopenia.

Cite this study APA, Vancouver, BibTeX · download .bib or .ris

APA 7th

Lipoeto, N. I., Vanoh, D., Desmawati, D., Ishak, W. R. W., & Mohamed, R. (2025). Determinants of dementia risk among older adults with probable sarcopenia and sarcopenia. BMC Public Health. https://doi.org/10.1186/s12889-025-22065-z

Vancouver

Lipoeto NI, Vanoh D, Desmawati D, Ishak WRW, Mohamed R. Determinants of dementia risk among older adults with probable sarcopenia and sarcopenia. BMC Public Health. 2025. doi:10.1186/s12889-025-22065-z. PMID: 40133853.

BibTeX

@article{lipoeto2025-40133853,
  author  = {Lipoeto, Nur Indrawaty and Vanoh, Divya and Desmawati, Desmawati and Ishak, Wan Rosli Wan and Mohamed, Rosminah},
  title   = {{Determinants of dementia risk among older adults with probable sarcopenia and sarcopenia}},
  journal = {BMC Public Health},
  year    = {2025},
  doi     = {10.1186/s12889-025-22065-z},
  pmid    = {40133853},
  url     = {https://doi.org/10.1186/s12889-025-22065-z}
}

Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. Check the citation against the original before you use it.

How to read this study

Design: our record does not state a study design, so check the methods section of the original before weighing the result.
Size: the record gives no participant count. Look for one in the original before trusting a pattern.
Effect: the record reports “66.1%; 64.3%; OR: 4.049”. A statistically significant result can still be small in daily life.

What the evidence grade means here

This page is graded low. alzhub.org assigns the grade automatically from keywords in the abstract, not from reading the paper. Low means the abstract matched neither pattern. It is the default label, and it does not mean the work is poor; many sound lab and imaging papers land here. It can add at most 5 of the 100 points in the study score, and it is a label about design, not a verdict on whether the findings are true.

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Key findings

Probable sarcopenia subjects with dementia were older (68.5(7.8) years old) as compared to those without dementia (66.0(6.0) years old).
Among the probable sarcopenia, 66.1% of the subjects with dementia had hypertension, while 64.3% of the sarcopenia subjects had hypertension.
Fat mass was significantly higher among dementia subjects with probable sarcopenia (33.0(6.5) %) as compared to non-dementia subjects (30.4(6.8) %).
Multivariate analysis revealed that hypertension (OR: 4.049; 95% CI: 1.510; 10.855, p = 0.005) was the only factor associated with dementia risk among older adults with probable sarcopenia and sarcopenia.
Hypertension is the only factors associated with risk of dementia after adjusting for potential confounders among older adults with probable sarcopenia and sarcopenia.

Why it matters

Among older adults with probable sarcopenia or sarcopenia, hypertension was the only factor associated with dementia risk after adjusting for confounders. The authors suggest good blood pressure control may lower dementia risk in these patients, but they call for clinical trials to confirm this.

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Study details

Effect size66.1%; 64.3%; OR: 4.049
Evidence strengthLow

How this study scored 40/100

Published in a peer-reviewed journal. Scored zero for study design, sample size, studied in people and randomized / blinded because the record does not state it. We have no data on senior author's track record, so that was left out: it earned 38 of the 96 points we could judge it on, which is 40 out of 100.

Component	Points	Why
Journal tier	7 / 10	Tier 3 — peer-reviewed journal (BMC Public Health)
Journal's citation record	3 / 4	BMC Public Health: journal h-index 289 (OpenAlex, 2026-10-29)
Study design	0 / 12	No study design recorded — scores zero, not guessed (not stated in the record — scored 0)
Strength of evidence	1 / 5	Rated “low” in our summary
Peer-review validation	10 / 10	Peer-reviewed. Published as an article in a named peer-reviewed journal.
How recent	4 / 5	2025 — within 3 year(s) of the newest study here
Sample size	0 / 4	Participant count not stated — scores zero (not stated in the record — scored 0)
Effect reported	3 / 3	Effect reported with a statistic (interval, p-value, ratio or similar)
Studied in people	0 / 3	Not stated whether this was studied in people — scores zero (not stated in the record — scored 0)
Randomized / blinded	0 / 2	No randomization or blinding stated — scores zero (not stated in the record — scored 0)
Times cited	1 / 7	Cited 3 times (OpenAlex, 2026-10-10)
Citations per year	1 / 5	1.0 citations a year over 3 year(s) since 2025
Impact for its field and year	2 / 6	Cited 1.6× the average for papers of its field and year (OpenAlex FWCI)
Cited by studies here	0 / 6	No other study in this library cites it
Still being cited	1 / 4	Cited 3 times in 2024–2026 (2026 still in progress; OpenAlex)
Senior author's track record	— / 4	OpenAlex's profile for last-listed author Rosminah Mohamed holds only 6 work(s), too few to judge a track record — left out of this score
Institution's track record	0 / 3	Universiti Sains Malaysia: institution h-index 482 (OpenAlex)
Multicenter collaboration	1 / 3	OpenAlex lists 2 institution(s) in 2 countries
Indexed in PubMed	2 / 2	Indexed in PubMed (PMID 40133853)
Free to read	2 / 2	Free to read
Points	38 / 96	Scored on 19 of 20 parts. We have no data for the rest, so they are left out: 38 of the 96 points we could judge it on is 40 out of 100.
Total	40 / 100	—

What each of these 20 components measures, and what this score is not →

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