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39/100

✓ Peer-reviewed alzhub usefulness score 39 out of 100. Mild cognitive impairment

Topic: Risk, prevention and care in population studies

Plain-language summary

At baseline, the mean ZBI score was 24.5 ± 15.2 and correlated positively with caregiver CES-D and STAI scores and with patient neuropsychiatric symptoms (NPI-frequency × severity) and distress felt by the caregiver (NPI-distress). At follow-up (17.7 ± 9.4 months) the mean ZBI score increased to 31.4 ± 16.3 (P < 0.001); however, no baseline caregiver or patient characteristics were identified associated with the evolution of caregiver burden. Caregivers of patients who received a diagnosis of MCI due to AD report substantial burden, that increased with time. Future studies should investigate caregiver characteristics that may predict burden progression and help delineate strategies to minimise it.

What this study adds

Evidence grade: Low

In caregivers of patients diagnosed with mild cognitive impairment due to Alzheimer's disease, burden increased over a mean follow-up of 17.7 months, but no baseline characteristics predicted this increase. This concerns caregiver burden, not treating, curing or preventing the disease.

Taken from this record’s own fields, not from reading the paper. The grade is assigned from the abstract’s wording; what that means.

Cite this study APA, Vancouver, BibTeX · download .bib or .ris

APA 7th

Rebolo, M., Marôco, J. P., de Mendonça, A., & Melo, G. (2025). Caregiver burden in mild cognitive impairment due to Alzheimer's disease—a longitudinal study. Psychogeriatrics. https://doi.org/10.1111/psyg.70033

Vancouver

Rebolo M, Marôco JP, de Mendonça A, Melo G. Caregiver burden in mild cognitive impairment due to Alzheimer's disease—a longitudinal study. Psychogeriatrics. 2025. doi:10.1111/psyg.70033. PMID: 40202055.

BibTeX

@article{rebolo2025-40202055,
  author  = {Rebolo, Margarida and Marôco, João Paulo and de Mendonça, Alexandre and Melo, Graça},
  title   = {{Caregiver burden in mild cognitive impairment due to Alzheimer's disease—a longitudinal study}},
  journal = {Psychogeriatrics},
  year    = {2025},
  doi     = {10.1111/psyg.70033},
  pmid    = {40202055},
  url     = {https://doi.org/10.1111/psyg.70033}
}

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How to read this study

Design: our record does not state a study design, so check the methods section of the original before weighing the result.
Size: the record gives no participant count. Look for one in the original before trusting a pattern.
Effect: the record gives no effect size, so the summary above cannot say how large any difference was.

What the evidence grade means here

This page is graded low. alzhub.org assigns the grade automatically from keywords in the abstract, not from reading the paper. Low means the abstract matched neither pattern. It is the default label, and it does not mean the work is poor; many sound lab and imaging papers land here. It can add at most 5 of the 100 points in the study score, and it is a label about design, not a verdict on whether the findings are true.

New to reading papers? Six questions to ask of any Alzheimer’s study · how we score.

Key findings

At baseline, the mean ZBI score was 24.5 ± 15.2 and correlated positively with caregiver CES-D and STAI scores and with patient neuropsychiatric symptoms (NPI-frequency × severity) and distress felt by the caregiver (NPI-distress).
At follow-up (17.7 ± 9.4 months) the mean ZBI score increased to 31.4 ± 16.3 (P < 0.001); however, no baseline caregiver or patient characteristics were identified associated with the evolution of caregiver burden.
Caregivers of patients who received a diagnosis of MCI due to AD report substantial burden, that increased with time.
Future studies should investigate caregiver characteristics that may predict burden progression and help delineate strategies to minimise it.

Why it matters

Study details

Evidence strengthLow

How this study scored 39/100

Published in a peer-reviewed journal. Scored zero for study design, sample size, effect reported, studied in people and randomized / blinded because the record does not state it.

Component	Points	Why
Journal tier	7 / 10	Tier 3 — peer-reviewed journal (Psychogeriatrics)
Journal's citation record	0 / 4	Psychogeriatrics: journal h-index 62 (OpenAlex, 2026-10-29)
Study design	0 / 12	No study design recorded — scores zero, not guessed (not stated in the record — scored 0)
Strength of evidence	1 / 5	Rated “low” in our summary
Peer-review validation	10 / 10	Peer-reviewed. Published as an article in a named peer-reviewed journal.
How recent	4 / 5	2025 — within 3 year(s) of the newest study here
Sample size	0 / 4	Participant count not stated — scores zero (not stated in the record — scored 0)
Effect reported	0 / 3	No effect size reported — scores zero (not stated in the record — scored 0)
Studied in people	0 / 3	Not stated whether this was studied in people — scores zero (not stated in the record — scored 0)
Randomized / blinded	0 / 2	No randomization or blinding stated — scores zero (not stated in the record — scored 0)
Times cited	2 / 7	Cited 12 times (OpenAlex, 2026-10-10)
Citations per year	2 / 5	4.0 citations a year over 3 year(s) since 2025
Impact for its field and year	3 / 6	Cited 7.6× the average for papers of its field and year (OpenAlex FWCI)
Cited by studies here	2 / 6	Cited by 4 other studies in this library
Still being cited	1 / 4	Cited 12 times in 2024–2026 (2026 still in progress; OpenAlex)
Senior author's track record	1 / 4	Last-listed author Graça Melo: h-index 6 (OpenAlex, whole career)
Institution's track record	0 / 3	University of Lisbon: institution h-index 605 (OpenAlex)
Multicenter collaboration	2 / 3	OpenAlex lists 4 institution(s) in 1 country
Indexed in PubMed	2 / 2	Indexed in PubMed (PMID 40202055)
Free to read	2 / 2	Free to read
Total	39 / 100	—

What each of these 20 components measures, and what this score is not →

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