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Association Between ICD ‐Coded Delirium and Health Determinants in The Atherosclerosis Risk in Communities Study
Mfon E. Umoh, Emmanuel E. Garcia Morales, Wuyang Zhang, Charles H Brown, Esther S. Oh, Nicholas S. Reed. Journal of the American Geriatrics Society, 2026-05-02
Topic: Risk, prevention and care in population studies
In this analytic cohort of 4130 participants, 486 (11.8%) experienced at least one hospitalization with delirium. Unadjusted regression analyses showed a higher incidence of delirium (proportion ratio, PR = 1.32; and 95% CI = 1.03, 1.69) and number of delirium events (incidence rate ratio, IRR = 1.30; 95% CI = 1.05, 1.63) among participants from the highest ADI quartile compared to the lowest quartile. In fully adjusted models, this association was attenuated. Among participants with mild cognitive impairment (MCI) and dementia, those from the most disadvantaged neighborhoods experienced a higher incidence and number of delirium events. In this cohort of hospitalized older adults, participants from more disadvantaged neighborhoods had a higher incidence of delirium; this association was attenuated in adjusted analyses. This suggests that neighborhood-level social disadvantage may be meaningful in studies on prevention and management of delirium, though overlapping demographic and clinical characteristics likely confound this relationship.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Umoh, M. E., Morales, E. E. G., Zhang, W., Brown, C. H., Oh, E. S., & Reed, N. S. (2026). Association Between ICD ‐Coded Delirium and Health Determinants in The Atherosclerosis Risk in Communities Study. Journal of the American Geriatrics Society. https://doi.org/10.1111/jgs.70447
Vancouver
Umoh ME, Morales EEG, Zhang W, Brown CH, Oh ES, Reed NS. Association Between ICD ‐Coded Delirium and Health Determinants in The Atherosclerosis Risk in Communities Study. Journal of the American Geriatrics Society. 2026. doi:10.1111/jgs.70447. PMID: 42068258.
BibTeX
@article{umoh2026-42068258,
author = {Umoh, Mfon E. and Morales, Emmanuel E. Garcia and Zhang, Wuyang and Brown, Charles H and Oh, Esther S. and Reed, Nicholas S.},
title = {{Association Between ICD ‐Coded Delirium and Health Determinants in The Atherosclerosis Risk in Communities Study}},
journal = {Journal of the American Geriatrics Society},
year = {2026},
doi = {10.1111/jgs.70447},
pmid = {42068258},
url = {https://doi.org/10.1111/jgs.70447}
}
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Key findings
- In this analytic cohort of 4130 participants, 486 (11.8%) experienced at least one hospitalization with delirium.
- Unadjusted regression analyses showed a higher incidence of delirium (proportion ratio, PR = 1.32; and 95% CI = 1.03, 1.69) and number of delirium events (incidence rate ratio, IRR = 1.30; 95% CI = 1.05, 1.63) among participants from the highest ADI quartile compared to the lowest quartile.
- In fully adjusted models, this association was attenuated.
- Among participants with mild cognitive impairment (MCI) and dementia, those from the most disadvantaged neighborhoods experienced a higher incidence and number of delirium events.
- In this cohort of hospitalized older adults, participants from more disadvantaged neighborhoods had a higher incidence of delirium; this association was attenuated in adjusted analyses.
Why it matters
In a cohort of 4,130 hospitalized older adults, those from the most disadvantaged neighborhoods had a higher incidence of delirium in unadjusted analyses, but this link weakened after adjusting for other factors. Among those with mild cognitive impairment and dementia, more disadvantaged neighborhoods were still linked to more delirium events, but the study does not test any treatment or prevention.
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Study details
- Study designprospective cohort
- Participants4,130
- Effect size11.8%; RR = 1.30
- Evidence strengthModerate
How this study scored 55/100
Published in a peer-reviewed journal, and it is a prospective cohort study, followed forward from enrollment. Scored zero for randomised / blinded because the record does not state it. We have no data on senior author's track record, so that was left out: it earned 53 of the 96 points we could judge it on, which is 55 out of 100.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Journal of the American Geriatrics Society) |
| Journal's citation record | 3 / 4 | Journal of the American Geriatrics Society: journal h-index 344 (OpenAlex, 2026-10-29) |
| Study design | 7 / 12 | A prospective cohort study, followed forward from enrollment |
| Strength of evidence | 3 / 5 | Rated “moderate” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 5 / 5 | 2026 — within 1 year(s) of the newest study here |
| Sample size | 3 / 4 | 4,130 participants |
| Effect reported | 3 / 3 | Effect reported with a statistic (interval, p-value, ratio or similar) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 0 / 7 | Cited 0 times (OpenAlex, 2026-10-10) |
| Citations per year | 0 / 5 | 0.0 citations a year over 2 year(s) since 2026 |
| Impact for its field and year | 0 / 6 | Cited 0.0× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 0 / 4 | Cited 0 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | — / 4 | OpenAlex's profile for last-listed author Nicholas S. Reed holds only 3 work(s), too few to judge a track record — left out of this score |
| Institution's track record | 3 / 3 | Stanford University: institution h-index 2,684 (OpenAlex) |
| Multi-centre collaboration | 2 / 3 | OpenAlex lists 5 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 42068258) |
| Free to read | 2 / 2 | Free to read |
| Points | 53 / 96 | Scored on 19 of 20 parts. We have no data for the rest, so they are left out: 53 of the 96 points we could judge it on is 55 out of 100. |
| Total | 55 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
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