27,780 Alzheimer's and dementia studies in plain English, each scored out of 100.
To evaluate the possible causality between Alzheimer disease (AD) and delirium, a two-sample Mendelian randomization (MR) method and gene colocalization strategy were employed. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
In 2021, LOAD demonstrated a substantially higher global burden than EOAD: incidence cases (8,455,150 [95% UI: 5,818,063-11,461,560] vs. 1,381,906 [894,768-1,963,453]), mortality cases (1,879,291 [471,472-4,968,222] vs. 73,386 [14,059-232,170]), and DALYs (32,558,570 [14,907,368-71,154,572] vs. 3,774,117 [1,696,439-8,881,154]). 5 key findings →
Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
Between 1990 and 2021, ADOD incidence, prevalence, deaths, and DALYs increased significantly. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Kening Jiang, Daniel D Callow, Adam P Spira; The Role of Sleep in Dementia Prevention: Building the Case for Causality, Sleep, , zsaf285, https://doi.org/1 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Dementia incidence was 0.89 per 1000 person-years. 5 key findings →
Evidence: moderate
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376 323 elective geriatric THA patient samples from the NIS database were included, with an overall dementia prevalence of 2.05%. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
We assessed the spatiotemporal patterns of hospitalization with comorbid cancer and dementia. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
S/SDOH can significantly impact health throughout the life course by determining access to health promoting resources and opportunities, which in turn impacts modifiable risk factors (e.g., diet, physical activity, social contact) known to influence Alzheimer’s disease and related dementia (ADRD) risk. 5 key findings →
Participants: 111 Evidence: moderate
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All the five dimensional SDOH disadvantages were significantly associated with higher odds of both dementia and MCI in the overall sample (p <0.05) (Figure 1). 5 key findings →
Participants: 3,229 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
There are factors, other than the step changes in underlying cause of death coding, driving the progressively increasing temporal trend in relative risk of dementia‐associated death. 2 key findings →
Design: cohort study Evidence: moderate
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Our study suggests that exposure to O3 is associated with the higher risk of dementia in American Indians. 4 key findings →
Participants: 14,910 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
(n = 399) have completed the first follow-up assessments, including MoCA, mCAIDE, memory self-report, demographic information. 5 key findings →
Participants: 399 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
We observed adults aged 50 years and older from the UK Biobank over a median observational period exceeding two years following COVID-19 infection. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
(1) To investigate the association between age at diabetes diagnosis and the incidence of all-cause dementia (ACD), Alzheimer’s disease (AD), and vascular dementia (VD) in individuals with diabetes. 4 key findings →
Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
Alzheimer's disease and related dementias (ADRD) affects millions of patients worldwide and is a leading cause of morbidity in older adults. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Residing in neighborhoods characterized by low-income, low-vehicle access, and higher low-fat milk prices was associated with a greater risk of incident dementia. 3 key findings →
Participants: 6,551 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
In adjusted analyses, low vs. high livability was associated with higher dementia prevalence (B=0.38; p-value=0.31). 5 key findings →
Participants: 46 Evidence: low
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The aging population is increasingly affected by both diabetes mellitus and hearing loss, two conditions that often coexist and can significantly impact quality of life. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
The findings indicate that the burden of dementia is rising in East and Southeast Asia, with women showing a higher burden across all indicators. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Delirium and dementia share similarities in clinical and pathogenic features, leading to the speculation that instead of being distinct clinical entities, the two age-related conditions may be linked by a common pathogenic mechanism. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
It is widely accepted that inflammation plays some role in the progression of chronic neurodegenerative diseases such as AD (Alzheimer's disease), but its precise role remains elusive. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Interest in dementia has increased over the past few decades. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Twenty-seven patients with Alzheimer-type dementia (ATD) were treated with bright light therapy in the morning for four consecutive weeks. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Full text may need a subscription
Higher per-capita food availability was positively associated with dementia outcomes in minimally adjusted models, particularly for the 2005 exposure window, although these associations were substantially attenuated after full covariate adjustment. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Vascular dementia (VaD) is the second commonest subtype of dementia after Alzheimer's disease (AD). 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Full text may need a subscription
9 of the 1,130 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 9. The same 9 appear here every time.
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 27,780 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,780 records, built mostly from automated pulls of Europe PMC (61.1% of the library) and OpenAlex (18.3%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,034 records (3.7% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →