27,380 Alzheimer's and dementia studies in plain English, each scored out of 100.
Importantly, delirium is not merely a transient cognitive fluctuation; it is independently associated with increased short- and long-term mortality, longer hospital stays, higher healthcare costs, and persistent cognitive impairment comparable to mild dementia[4,5]. 5 key findings →
Evidence: low
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BackgroundWith the growing demand for dementia-friendly care environments, existing smart room designs often lack systematic methods to translate user needs into functional solutions. 5 key findings →
Evidence: low
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Various negative and positive aspects, along with specific needs, were identified. 5 key findings →
Evidence: low
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Three hundred fourteen articles from 48 countries were included. 5 key findings →
Evidence: low
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Voluntary assisted dying (VAD) is an end-of-life care option available to eligible Australians living with a terminal condition, though people living with dementia are typically ineligible to choose VAD as part of their end-of-life care. 5 key findings →
Evidence: low
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A balanced understanding of dementia’s impact (acknowledging both continuity and loss, alternatives and socially constructed aspects) better reflects the realities of dementia and creates new possibilities for supportive care practices to improve pain management and quality of life. 5 key findings →
Evidence: low
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Prion diseases are fatal neurological disorders characterized by the accumulation of abnormal proteins in the central nervous system, leading to rapid neurodegeneration. 1 key finding →
Evidence: low
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These inputs and activities were shown in the logic model to result in short, medium, and long-term outcomes, including reduced healthcare resource use and increased quality of life for people with dementia at the end of life. 2 key findings →
Participants: 18 Evidence: low
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White matter hyperintensity (WMH) is the core imaging hallmark of cerebral small vessel disease (CSVD). 2 key findings →
Evidence: low
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This study aimed to determine the effectiveness of regular dental scaling by evaluating the association between the frequency of dental scaling and the risk of dementia in individuals with moderate to severe periodontal disease. 2 key findings →
Evidence: moderate
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This study explored the ways in which food desert coverage was reported during the COVID-19 pandemic. 1 key finding →
Participants: 85 Evidence: low
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The model outperformed conventional ones, with an out-of-bag R2 of 74.8%. 3 key findings →
Evidence: low
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The prevalence of hypertension showed statistically significant spatial clustering (global Moran’s I=0.442, p<.001), with high-high clusters concentrated in rural eup-myeon areas and low-low clusters in urban dong areas. 4 key findings →
Participants: 62,411 Evidence: low
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Our case series highlighted the relevance of neurological comorbidities in BP patients; although the pathogenesis is still to be elucidated, the neuroinflammation present in neurodegenerative diseases could explain the neurocutaneous link and the chronological relationship between these entities. 3 key findings →
Participants: 257 Evidence: low
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Dementia arising in patients with Parkinson disease or parkinsonian neurodegeneration comprises a heterogeneous neuropathology. 1 key finding →
Evidence: low
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Clinical indications of amyloid imaging in atypical dementia remain unclear. 3 key findings →
Evidence: low
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The precise regulation of DSCR gene expression is crucial to maintain the brain homeostasis, especially in those areas with high levels of gene expression associated with a remarkable process of learning and cognition. 3 key findings →
Evidence: low
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Recently, an increasing number of genes have been associated with global developmental delay (GDD) and intellectual disability (ID). 5 key findings →
Evidence: low
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We performed a retrospective analysis of the patients assessed at our memory unit for whom Alzheimer disease (AD) cerebrospinal fluid biomarker results were available. 4 key findings →
Evidence: low
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A Cognitive Task Force (CTF) was established for the MissionAD program with the aim of reducing the screen failure (SF) rate to ∼30% and thereby reduce unnecessary subject burden, site burden, and excess trial costs. 4 key findings →
Design: clinical trial Evidence: low
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Previously, we found that circadian desynchrony was involved in isoflurane-induced cognitive impairment. 4 key findings →
Evidence: low
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Alzheimer’s disease and related dementias (ADRD) disproportionately impact older Black American adults, with diet-related cardiometabolic conditions contributing to increased risk. 1 key finding →
Evidence: low
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120 patients were included in the audit with a confirmed stroke on CTB/MRI. 5 key findings →
Participants: 44 Evidence: moderate
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Among Medicare beneficiaries from 2008 to 2018, AD prevalence was generally stable, while MCI increased. 2 key findings →
Evidence: low
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There were few differences in how MA plan characteristics affected choice among older adults with and without dementia. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled.
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 27,380 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,380 records, built mostly from automated pulls of Europe PMC (60.6% of the library) and OpenAlex (18.6%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,032 records (3.8% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →