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Newest in this topic

  1. Alcohol use disorder accelerates age-related cognitive decline 2026-09-23
  2. A longitudinal study of age-related traits and cognitive function: The Collaborative Amish Aging and Memory Project (CAAMP) 2026-09-20
  3. Associations of menopause hormone therapy with late-life cognition and brain health vary by formulation and APOEε4 presence 2026-09-20

Studies

1,138 studies carry this tag.

Date range

1986 to 2026

Top journals

  • Alzheimer s & Dementia 42
  • Neurology 41
  • Journal of the American Geriatrics Society 36
  • Journal of Alzheimer's disease : JAD 33
  • Nutrients 23

437 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Evaluation of Neighborhood-Level Disadvantage and Cognition in Mexican American and Non-Hispanic White Adults 50 Years and Older in the US

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. JAMA Network Open 2023-08-30 Risk factors

    Among 1614 older adults (mean [SD] age, 66.3 [8.7] years; 980 women [60.7%]), 853 were Mexican American (mean [SD] age, 63.9 [7.9] years; 566 women [66.4%]), and 761 were non-Hispanic White (mean [SD] age, 69.1 [8.7] years; 414 women [54.4%]).

  2. Platelet factors attenuate inflammation and rescue cognition in ageing

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Nature 2023-08-16 Inflammation and the immune system

    Identifying therapeutics to delay, and potentially reverse, age-related cognitive decline is critical in light of the increased incidence of dementia-related disorders forecasted in the growing older population 1 .

  3. Hearing intervention versus health education control to reduce cognitive decline in older adults with hearing loss in the USA (ACHIEVE): a multicentre, randomised controlled trial

    ✓ Peer-reviewed alzhub usefulness score 84 out of 100. Lancet (London, England) 2023-07-18 Prevention and risk

    These findings suggest that a hearing intervention might reduce cognitive change over 3 years in populations of older adults at increased risk for cognitive decline but not in populations at decreased risk for cognitive decline.

  4. Trial of the MIND Diet for Prevention of Cognitive Decline in Older Persons

    ✓ Peer-reviewed alzhub usefulness score 87 out of 100. New England Journal of Medicine 2023-07-18 Prevention and risk

    Among cognitively unimpaired participants with a family history of dementia, changes in cognition and brain MRI outcomes from baseline to year 3 did not differ significantly between those who followed the MIND diet and those who followed the control diet with mild caloric restriction.

  5. Brain structure and phenotypic profile of superagers compared with age-matched older adults: a longitudinal analysis from the Vallecas Project

    ✓ Peer-reviewed alzhub usefulness score 61 out of 100. The lancet. Healthy longevity 2023-07-13 Digital health tools

    We aimed to characterise the brain structure of superagers and identify demographic, lifestyle, and clinical factors associated with this phenotype.

  6. Anxiety adds the risk of cognitive progression and is associated with axon/synapse degeneration among cognitively unimpaired older adults

    ✓ Peer-reviewed alzhub usefulness score 56 out of 100. EBioMedicine 2023-07-08 Long-term cohort studies

    Mental symptoms have been shown to be associated with dementia.

  7. In this clinical trial, older adults with MCI receiving aerobic-resistance exercises with sequential computerized cognitive training significantly improved cognition, although some results were inconsistent.

  8. Effects of Meditation Training and Non-Native Language Training on Cognition in Older Adults: A Secondary Analysis of a Randomized Clinical Trial

    ✓ Peer-reviewed alzhub usefulness score 65 out of 100. JAMA network open 2023-07-03 Treatments

    Among 137 randomized participants, 2 were excluded for not meeting eligibility criteria, leaving 135 (mean [SD] age, 69.3 [3.8] years; 83 female [61%]) eligible for analysis.

  9. Sleep Architecture, Obstructive Sleep Apnea, and Cognitive Function in Adults

    ✓ Peer-reviewed alzhub usefulness score 80 out of 100. JAMA network open 2023-07-03 Long-term cohort studies

    Good sleep is essential for health, yet associations between sleep and dementia risk remain incompletely understood.

  10. Sleep duration is linked to amyloid-β clearance while physical activity is associated with brain volume maintenance.

  11. Association of the Mediterranean Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) Diet With the Risk of Dementia

    ✓ Peer-reviewed alzhub usefulness score 81 out of 100. JAMA Psychiatry 2023-06-01 Prevention and risk

    Further studies are warranted to develop and refine the specific MIND diet for different populations.

  12. Low circulating adropin concentrations predict increased risk of cognitive decline in community-dwelling older adults

    ✓ Peer-reviewed alzhub usefulness score 49 out of 100. GeroScience 2023-05-26 Biomarkers

    The secreted peptide adropin is highly expressed in human brain tissues and correlates with RNA and proteomic risk indicators for dementia.

  13. Cardiometabolic multimorbidity, lifestyle behaviours, and cognitive function: a multicohort study

    ✓ Peer-reviewed alzhub usefulness score 67 out of 100. The lancet. Healthy longevity 2023-05-04 Vascular contributions

    An increasing number of cardiometabolic diseases was dose-dependently associated with the decline in cognitive function score (one disease, β=-0·15 [95% CI -0·17 to -0·13]; two diseases, β=-0·37 [-0·40 to -0·34]; three diseases, β=-0·57 [-0·64 to -0·50]), with comorbid diabetes and stroke (β=-0·23 [-0·29 to -0·17]) contributing most strongly to cardiometabolic disease-associated cognitive decline.

  14. Mediterranean-Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) Diet and Cognitive Function and its Decline: A Prospective Study and Meta-analysis of Cohort Studies

    ✓ Peer-reviewed alzhub usefulness score 78 out of 100. The American journal of clinical nutrition 2023-04-25 Prevention trials

    Our findings suggest that higher adherence to the MIND diet was associated with better cognitive function and potentially slower cognitive decline in later life.

  15. Effectiveness of computer-based interventions for community-dwelling people with cognitive decline: a systematic review with meta-analyses

    ✓ Peer-reviewed alzhub usefulness score 56 out of 100. BMC geriatrics 2023-04-12 Digital health tools

    The results demonstrated that CCIs have beneficial effects on domain-specific cognition in people with MCI but no significant effects on people with dementia.

  16. Serious Games for Learning Among Older Adults With Cognitive Impairment: Systematic Review and Meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Journal of medical Internet research 2023-04-12 Treatments

    The results of the included studies were summarized using a narrative synthesis or meta-analysis, as appropriate.

  17. Nutrition and cognitive health: A life course approach

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Frontiers in public health 2023-03-27 Prevention and risk

    Multiple factors affect cognitive health, such as age-related changes in the brain, injuries, mood disorders, substance abuse, and diseases.

  18. Food Insecurity and Cognitive Trajectories in Community-Dwelling Medicare Beneficiaries 65 Years and Older

    ✓ Peer-reviewed alzhub usefulness score 63 out of 100. JAMA Network Open 2023-03-24 Risk factors

    Of 3037 participants, a weighted 57.8% (raw count, 1345) were younger than 75 years, 56.2% (raw count, 1777) were women, and most (84.9% [raw count, 2268]) were White.

  19. Cognitive Health in Persons With Human Immunodeficiency Virus: The Impact of Early Treatment, Comorbidities, and Aging

    ✓ Peer-reviewed alzhub usefulness score 67 out of 100. The Journal of Infectious Diseases 2023-03-15 Risk factors

    As persons with HIV age, noninfectious comorbidities occur more frequently compared with persons without HIV.

  20. Association between Periodontal Disease and Cognitive Impairment in Adults

    ✓ Peer-reviewed alzhub usefulness score 63 out of 100. International journal of environmental research and public health 2023-03-07 Inflammation and the immune system

    All the included studies show evidence of an association between periodontitis and cognitive impairment or dementia and Alzheimer's disease pathology.

  21. Social Determinants of Health and Traumatic Brain Injury: Implications for Rehabilitation Service Delivery and Outcomes

    ✓ Peer-reviewed alzhub usefulness score 34 out of 100. Journal of Head Trauma Rehabilitation 2023-03-01 Risk factors

    Taken together, findings weave a relatively cohesive narrative: recovery from TBI is inextricably connected to social forces, and such forces warrant increased attention in TBI care and research.

  22. The association of MIND diet with cognitive resilience to neuropathologies

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2023-02-28 Prevention trials

    The MIND diet is associated with both higher cognition and slower rates of cognitive decline, after controlling for neuropathology, indicating the MIND diet may be important to cognitive resilience.

  23. New Opportunities for the Early Detection and Treatment of Cognitive Decline: Adherence Challenges and the Promise of Smart and Person-Centered Technologies

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. BMC digital health 2023-02-14 Prevention trials

    Early detection of age-related cognitive decline has transformative potential to advance the scientific understanding of cognitive impairments and possible treatments by identifying relevant participants for clinical trials.

  24. The role of nutrition and the Mediterranean diet on the trajectories of cognitive decline

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Experimental gerontology 2023-02-02 Prevention trials

    The worldwide burden of dementia is immense, and set to increase to unprecedented levels in the coming decades, due to population aging.

  25. Association Between Consumption of Ultraprocessed Foods and Cognitive Decline

    ✓ Peer-reviewed alzhub usefulness score 72 out of 100. JAMA Neurology 2023-02-01 Prevention and risk

    A higher percentage of daily energy consumption of ultraprocessed foods was associated with cognitive decline among adults from an ethnically diverse sample.

  26. Association of Hearing Aids and Cochlear Implants With Cognitive Decline and Dementia: A Systematic Review and Meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 79 out of 100. JAMA Neurology 2023-02-01 Prevention and risk

    In this meta-analysis, the usage of hearing restorative devices by participants with hearing loss was associated with a 19% decrease in hazards of long-term cognitive decline.

  27. Cognitive stimulation to improve cognitive functioning in people with dementia

    ✓ Peer-reviewed alzhub usefulness score 74 out of 100. The Cochrane database of systematic reviews 2023-01-31 Digital health tools

    Where appropriate, we undertook subgroup analysis by modality (individual versus group), number of sessions and frequency, setting (community versus care home), type of control condition and dementia severity.

  28. Effects of Transcranial Pulse Stimulation (TPS) on Adults with Symptoms of Depression-A Pilot Randomized Controlled Trial

    ✓ Peer-reviewed alzhub usefulness score 67 out of 100. International journal of environmental research and public health 2023-01-28 Treatments

    Transcranial pulse stimulation (TPS) is a recent development in non-invasive brain stimulations (NIBS) that has been proven to be effective in terms of significantly improving Alzheimer patients' cognition, memory, and execution functions.

  29. The beneficial effect on cognition of noninvasive brain stimulation intervention in patients with dementia: a network meta-analysis of randomized controlled trials

    ✓ Peer-reviewed alzhub usefulness score 63 out of 100. Alzheimer's research & therapy 2023-01-25 Treatments

    The present findings provide evidence of the benefits of NIBS, especially tDCS, for beneficial effect on cognition in patients with AD.

  30. Whole Dietary Patterns, Cognitive Decline and Cognitive Disorders: A Systematic Review of Prospective and Intervention Studies

    ✓ Peer-reviewed alzhub usefulness score 78 out of 100. Nutrients 2023-01-09 Prevention trials

    Dementia prevalence is a global public health concern.

  31. Mediterranean Diet, Ketogenic Diet or MIND Diet for Aging Populations with Cognitive Decline: A Systematic Review

    ✓ Peer-reviewed alzhub usefulness score 81 out of 100. Life (Basel, Switzerland) 2023-01-06 Prevention trials

    Only RCTs were included in this study; there were eleven studies ( n = 2609 participants) of the Mediterranean diet, seven studies ( n = 313) of the ketogenic diet and one study ( n = 37) of the MIND diet.

  32. Brain Aging Among Racially and Ethnically Diverse Middle-Aged and Older Adults

    ✓ Peer-reviewed alzhub usefulness score 65 out of 100. JAMA neurology 2023-01-01 Brain scans and imaging

    Offspring participants (497 [33.9%]) had a mean (SD) age of 55 (10.7) years, had a mean (SD) of 13 (3.5) years of education, and included 117 Black individuals (23.5%), 348 Latinx individuals (70%), 32 White individuals (6.4%), and 324 women (65.2%).

  33. Effectiveness of online-based cognitive intervention in community-dwelling older adults with cognitive dysfunction: A systematic review and meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 71 out of 100. International journal of geriatric psychiatry 2023-01-01 Prevention trials

    ICT-based cognitive intervention had a positive effect on cognitive function, depression, and quality of life in older adults with MCI or mild dementia.

  34. Nutrition Strategies Promoting Healthy Aging: From Improvement of Cardiovascular and Brain Health to Prevention of Age-Associated Diseases

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Nutrients 2022-12-22 Prevention trials

    Certain diets, such as the Mediterranean diet, may play a significant role in healthy aging by preventing the onset of certain diseases and by improving the aging process itself.

  35. Cochlear Implants Now More Accessible to Older Adults

    ✓ Peer-reviewed alzhub usefulness score 28 out of 100. The Hearing Journal 2022-12-17 Risk factors

    Benefits Beyond Auditory Rehabilitation Research conducted by Frank Lin and colleagues found that individuals with untreated mild, moderate, and severe hearing loss had, respectively, a twofold, threefold, and fivefold increased risk of dementia compared with individuals with normal hearing. 4 Research suggests that early auditory rehabilitation is important for people of all ages, including older adults, as it can provide benefits and improvements beyond hearing ability such as cognitive function and mitigation of depression.

  36. Dispositional inward anger expression may increase susceptibility to the detrimental impacts of neighborhood disadvantage on cognitive health.

  37. Effects of Mindfulness Training and Exercise on Cognitive Function in Older Adults: A Randomized Clinical Trial

    ✓ Peer-reviewed alzhub usefulness score 84 out of 100. JAMA 2022-12-01 Hippocampus size on brain scans

    Among older adults with subjective cognitive concerns, mindfulness training, exercise, or both did not result in significant differences in improvement in episodic memory or executive function at 6 months.

  38. Hearing impairment is associated with cognitive decline, brain atrophy and tau pathology

    ✓ Peer-reviewed alzhub usefulness score 65 out of 100. EBioMedicine 2022-11-07 Long-term cohort studies

    Hearing impairment was recently identified as the most prominent risk factor for dementia.

  39. ASSOCIATION BETWEEN VIOLENT CRIME INCIDENT PROXIMITY AND COGNITIVE FUNCTION IN OLDER AFRICAN AMERICANS

    ✓ Peer-reviewed alzhub usefulness score 35 out of 100. Innovation in Aging 2022-11-01 Risk factors

    Research on Area Deprivation Index (ADI) suggests that the built environment and neighborhood stressors (e.g., violent crime incidents) play a role in later-life cognitive function.

  40. FOOD INSECURITY AND COGNITIVE TRAJECTORIES IN COMMUNITY-DWELLING OLDER ADULTS

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Innovation in Aging 2022-11-01 Risk factors

    Each year’s cognitive functions were linked to the prior year’s food insecurity values.

  41. Effectiveness of Computerized Cognitive Training in Delaying Cognitive Function Decline in People With Mild Cognitive Impairment: Systematic Review and Meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 81 out of 100. Journal of medical Internet research 2022-10-27 Prevention trials

    This systematic review suggests that CCT interventions could improve global cognitive function in patients with MCI.

  42. Effect of Exercise Training or Complex Mental and Social Activities on Cognitive Function in Adults With Chronic Stroke: A Randomized Clinical Trial

    ✓ Peer-reviewed alzhub usefulness score 69 out of 100. JAMA network open 2022-10-03 Treatments

    One-hundred and twenty participants, with a mean (range) of 1.2 (1-4) strokes, a mean (SD) of 66.5 (53.8) months since the most recent stroke, mean (SD) baseline age of 70 (8) years, mean (SD) baseline ADAS-Cog-Plus of 0.22 (0.81), and 74 (62%) male participants, were randomized to EX (34 participants), ENRICH (34 participants), or BAT (52 participants).

  43. Effects of postoperative cognitive training on neurocognitive decline after heart surgery: a randomized clinical trial

    ✓ Peer-reviewed alzhub usefulness score 74 out of 100. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2022-10-01 Prevention trials

    Since our cognitive training showed beneficial effects, it could be a promising method to prevent POCD.

  44. Effect of a Digital Literacy Program on Older Adults' Digital Social Behavior: A Quasi-Experimental Study

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. International journal of environmental research and public health 2022-09-29 Digital health tools

    In South Korea, digital literacy education programs are expected to help its older population participate in online welfare services to increase their social support, self-esteem and well-being.

  45. Overall, 68 studies were included in the meta-analyses.

  46. Association between urate-lowering therapies and cognitive decline in community-dwelling older adults

    ✓ Peer-reviewed alzhub usefulness score 58 out of 100. Scientific reports 2022-09-12 Treatments

    Long-term use of urate-lowering therapies (ULT) may reduce inflammaging and thus prevent cognitive decline during aging.

  47. Unifying framework for cognitive training interventions in brain aging

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Ageing research reviews 2022-08-27 Prevention trials

    Cognitive training is a promising tool for slowing or preventing cognitive decline in older adults at-risk for dementia.

  48. Home-Based Transcranial Direct Current Stimulation to Enhance Cognition in Stroke: Randomized Controlled Trial

    ✓ Peer-reviewed alzhub usefulness score 76 out of 100. Stroke 2022-08-17 Prevention trials

    RS-tDCS is a safe and feasible rehabilitation modality for poststroke cognitive dysfunction.

  49. Catastrophic health expenditure among Chinese adults living alone with cognitive impairment: findings from the CHARLS

    ✓ Peer-reviewed alzhub usefulness score 54 out of 100. BMC Geriatrics 2022-08-03 Health systems and care delivery

    In comparison with participants living with others and with normal cognition, those adults living alone with cognitive impairment reported a higher percentage of catastrophic health expenditure (19.5% vs. 11.8%, respectively, P < 0.001).

  50. The Link between Obstructive Sleep Apnea and Neurocognitive Impairment: An Official American Thoracic Society Workshop Report

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. Annals of the American Thoracic Society 2022-08-01 Disparities

    There is emerging evidence that obstructive sleep apnea (OSA) is a risk factor for preclinical Alzheimer's disease (AD).

From across this tag

9 of the 1,130 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 9. The same 9 appear here every time.

All topic tags with their study counts