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Home › Research › Topics › pet

pet

1,163 studies tagged pet, dated 1983-08-01 to 2026-11-01. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Large-scale head-to-head comparison of on- and off-target profiles of [18F]Tauvid and [18F]MK6240 tau-PET in aging and Alzheimer’s disease 2026-11-01
  2. Detection of tau spatial extent using MK6240 and flortaucipir PET 2026-10-28
  3. Soluble amyloid composition links proximal APP processing, fibrillar burden and the p-tau181 response 2026-10-22

Studies

1,163 studies carry this tag.

Date range

1983 to 2026

Top journals

  • Neurology 88
  • Alzheimer's & dementia : the journal of the Alzheimer's Association 58
  • Brain : a journal of neurology 52
  • Journal of nuclear medicine : official publication, Society of Nuclear Medicine 52
  • Alzheimer's research & therapy 34

337 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Binding characteristics of [18F]PI-2620 distinguish the clinically predicted tau isoform in different tauopathies by PET

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2021-05-27 Brain scans and imaging

    The novel tau-PET tracer [18F]PI-2620 detects the 3/4-repeat-(R)-tauopathy Alzheimer's disease (AD) and the 4R-tauopathies corticobasal syndrome (CBS) and progressive supranuclear palsy (PSP).

  2. Cortical Thickness from MRI to Predict Conversion from Mild Cognitive Impairment to Dementia in Parkinson Disease: A Machine Learning-based Model

    ✓ Peer-reviewed alzhub usefulness score 46 out of 100. Radiology 2021-05-25 Digital health tools

    Cortical thickness from MRI helped predict conversion from mild cognitive impairment to dementia in Parkinson disease at an individual level, with improved performance when integrated with clinical variables. © RSNA, 2021 Online supplemental material is available for this article.

  3. P-tau/Aβ42 and Aβ42/40 ratios in CSF are equally predictive of amyloid PET status

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. Alzheimer's & dementia (Amsterdam, Netherlands) 2021-05-18 Biomarkers

    These data suggest that p-tau/Aβ42 and Aβ42/40 ratios provide similar clinical information in the assessment of amyloid pathology.

  4. Validation of amyloid PET positivity thresholds in centiloids: a multisite PET study approach

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Alzheimer's research & therapy 2021-05-10 Brain scans and imaging

    The FBB threshold based on the young sample (1.08; 18 CL) was consistent with that of the data-driven approach (1.10; 21 CL), and the existing FBP threshold converted to CL with the derived transformation (1.11; 20 CL).

  5. Cortical [18 F]PI-2620 Binding Differentiates Corticobasal Syndrome Subtypes

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Movement disorders : official journal of the Movement Disorder Society 2021-05-05 Brain scans and imaging

    Twenty-four percent (11 of 45) were β-amyloid-positive.

  6. Characterization of Alzheimer's tau biomarker discordance using plasma, CSF, and PET

    ✓ Peer-reviewed alzhub usefulness score 61 out of 100. Alzheimer's research & therapy 2021-05-04 Brain scans and imaging

    Across different tau biomarker groups, the proportion of participants with a discordant profile varied (plasma+/CSF- 15.6%, plasma-/CSF+ 15.3%, plasma+/PET- 22.4%, and plasma-/PET+ 6.1%).

  7. Association of Intensive vs Standard Blood Pressure Control With Magnetic Resonance Imaging Biomarkers of Alzheimer Disease: Secondary Analysis of the SPRINT MIND Randomized Trial

    ✓ Peer-reviewed alzhub usefulness score 71 out of 100. JAMA neurology 2021-05-01 Treatments

    Intensive treatment was associated with a small but statistically significant greater decrease in hippocampal volume compared with standard treatment, consistent with the observation that intensive treatment is associated with greater decreases in total brain volume.

  8. Four distinct trajectories of tau deposition identified in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 71 out of 100. Nature medicine 2021-04-29 Brain scans and imaging

    Alzheimer's disease (AD) is characterized by the spread of tau pathology throughout the cerebral cortex.

  9. Measures of resting state EEG rhythms for clinical trials in Alzheimer's disease: Recommendations of an expert panel

    ✓ Peer-reviewed alzhub usefulness score 54 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2021-04-15 Mild cognitive impairment

    The Electrophysiology Professional Interest Area (EPIA) and Global Brain Consortium endorsed recommendations on candidate electroencephalography (EEG) measures for Alzheimer's disease (AD) clinical trials.

  10. Transfer Learning in Magnetic Resonance Brain Imaging: A Systematic Review

    ✓ Peer-reviewed alzhub usefulness score 42 out of 100. Journal of imaging 2021-04-01 Digital health tools

    We found 129 articles that applied transfer learning to MR brain imaging tasks.

  11. Early detection of amyloid load using 18F-florbetaben PET

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Alzheimer's research & therapy 2021-03-27 Brain scans and imaging

    SUVR using the whole cerebellum as the reference region and centiloid (CL) cutoffs for early and established amyloid pathology were 1.10 (13.5 CL) and 1.24 (35.7 CL), respectively.

  12. Population-based blood screening for preclinical Alzheimer's disease in a British birth cohort at age 70

    ✓ Peer-reviewed alzhub usefulness score 62 out of 100. Brain : a journal of neurology 2021-03-01 Biomarkers

    Mass spectrometry plasma measures performed significantly better than any other measure (amyloid-β1-42/1-40: 0.817; 0.770-0.864 and amyloid-β composite: 0.820; 0.775-0.866).

  13. Clinical Relevance of [18F]Florbetaben and [18F]FDG PET/CT Imaging on the Management of Patients with Dementia

    ✓ Peer-reviewed alzhub usefulness score 44 out of 100. Molecules (Basel, Switzerland) 2021-02-26 Tau biomarkers

    PET of β-Amyloid plaques (Aβ) using [ 18 F ] florbetaben ( [ 18 F ] FBB) and [ 18 F ] fluorodeoxyglucose ( [ 18 F ] FDG) increasingly aid clinicians in early diagnosis of dementia, including Alzheimer's disease (AD), frontotemporal disease, dementia with Lewy bodies, and vascular dementia.

  14. Pinpointing Brain TREM2 Levels in Two Mouse Models of Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Molecular imaging and biology 2021-02-23 TREM2 and immune genetics

    Transgenic animals displayed higher total exposure, calculated as the AUC based on SUV determined at 24h, 48h, and 72h post injection, of PET radioligand [124I]mAb1729-scFv8D3CL than WT mice.

  15. Imaging Techniques in Alzheimer's Disease: A Review of Applications in Early Diagnosis and Longitudinal Monitoring

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. International journal of molecular sciences 2021-02-20 Hippocampus size on brain scans

    Reduced hippocampal volume is a biomarker for neurodegeneration, but atrophy is not an AD-specific measure.

  16. Data-driven FDG-PET subtypes of Alzheimer's disease-related neurodegeneration

    ✓ Peer-reviewed alzhub usefulness score 51 out of 100. Alzheimer's research & therapy 2021-02-19 Long-term cohort studies

    Previous research has described distinct subtypes of Alzheimer's disease (AD) based on the differences in regional patterns of brain atrophy on MRI.

  17. Machine Learning Algorithms and Statistical Approaches for Alzheimer's Disease Analysis Based on Resting-State EEG Recordings: A Systematic Review

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. International journal of neural systems 2021-02-16 Digital health tools

    Alzheimer's Disease (AD) is a neurodegenerative disorder and the most common type of dementia with a great prevalence in western countries.

  18. Plasma d-glutamate levels for detecting mild cognitive impairment and Alzheimer's disease: Machine learning approaches

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Journal of psychopharmacology (Oxford, England) 2021-02-15 Digital health tools

    This study aimed to use peripheral plasma d-glutamate levels to differentiate patients with mild cognitive impairment (MCI) and Alzheimer's disease (AD) from healthy individuals and to evaluate its prediction ability using machine learning.

  19. Amyloid PET Imaging in Self-Identified Non-Hispanic Black Participants of the Anti-Amyloid in Asymptomatic Alzheimer's Disease (A4) Study

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Neurology 2021-02-10 Treatments

    Reduced amyloid was observed in self-identified NHB participants who passed initial eligibility criteria for the A4 study.

  20. Association Between Ambient Air Pollution and Amyloid Positron Emission Tomography Positivity in Older Adults With Cognitive Impairment

    ✓ Peer-reviewed alzhub usefulness score 62 out of 100. JAMA neurology 2021-02-01 Biomarkers

    The data set included 18 178 patients, of which 10 991 (60.5%) had MCI and 7187 (39.5%) had dementia (mean [SD] age, 75.8 [6.3] years; 9333 women [51.3%]).

  21. Untangling the association of amyloid-β and tau with synaptic and axonal loss in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Brain : a journal of neurology 2021-02-01 Biomarkers

    It is currently unclear how amyloid-β and tau deposition are linked to changes in synaptic function and axonal structure over the course of Alzheimer's disease.

  22. A multilayer multimodal detection and prediction model based on explainable artificial intelligence for Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 76 out of 100. Scientific reports 2021-01-29 Digital health tools

    As a result, physicians struggle to interpret these models, and feel it is hard to trust them.

  23. Mild behavioral impairment and its relation to tau pathology in preclinical Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Translational psychiatry 2021-01-26 Brain scans and imaging

    Mild behavioral impairment (MBI) is suggested as risk marker for neurodegenerative diseases, such as Alzheimer's disease (AD).

  24. Head-to-head comparison of amplified plasmonic exosome Aβ42 platform and single-molecule array immunoassay in a memory clinic cohort

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. European journal of neurology 2021-01-23 Biomarkers

    Compared to Simoa biomarkers, APEX-Aβ42 showed significantly higher correlations with amyloid PET retention values and excellent diagnostic performance (sensitivity 100%, specificity 93.3%, area under the curve 0.995).

  25. Deep Learning-Based Classification and Voxel-Based Visualization of Frontotemporal Dementia and Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. Frontiers in neuroscience 2021-01-21 Long-term cohort studies

    Frontotemporal dementia (FTD) and Alzheimer's disease (AD) have overlapping symptoms, and accurate differential diagnosis is important for targeted intervention and treatment.

  26. A Transfer Learning Approach for Early Diagnosis of Alzheimer's Disease on MRI Images

    ✓ Peer-reviewed alzhub usefulness score 51 out of 100. Neuroscience 2021-01-17 Long-term cohort studies

    Mild cognitive impairment (MCI) detection using magnetic resonance image (MRI), plays a crucial role in the treatment of dementia disease at an early stage.

  27. Matching Clinical Diagnosis and Amyloid Biomarkers in Alzheimer's Disease and Frontotemporal Dementia

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Journal of personalized medicine 2021-01-14 Brain scans and imaging

    Amyloid-PET presented higher diagnostic accuracy, sensitivity, and NPV than CSF Aβ1-42 but not Aβ42/40 ratio.

  28. An MRI-based strategy for differentiation of frontotemporal dementia and Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 49 out of 100. Alzheimer's research & therapy 2021-01-12 Long-term cohort studies

    The differential diagnosis of frontotemporal dementia (FTD) and Alzheimer's disease (AD) is difficult due to the overlaps of clinical symptoms.

  29. Modular machine learning for Alzheimer's disease classification from retinal vasculature

    ✓ Peer-reviewed alzhub usefulness score 51 out of 100. Scientific reports 2021-01-08 Digital health tools

    Alzheimer's disease is the leading cause of dementia.

  30. Flortaucipir (tau) PET in LGI1 antibody encephalitis

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Annals of clinical and translational neurology 2021-01-07 Brain scans and imaging

    The contributors to persistent cognitive impairment and hippocampal atrophy in leucine-rich glioma-inactivated 1 antibody encephalitis (LGI1) patients are unknown.

  31. Association of Aβ deposition and regional synaptic density in early Alzheimer's disease: a PET imaging study with [11C]UCB-J

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Alzheimer's research & therapy 2021-01-05 Disease mechanisms

    Our findings lend support to a model in which fibrillar Aβ is still accumulating in the early stages of clinical disease but approaching a relative plateau, a point at which Aβ may uncouple from neurodegenerative processes including synaptic loss.

  32. Heterogeneity of Tau Deposition and Microvascular Involvement in MCI and AD

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Current Alzheimer research 2021 Brain scans and imaging

    High tau PET signal was generally observed in the lateral temporal and parietal cortices, with uptake in the occipital cortex in one subject.

  33. Multi-View Separable Pyramid Network for AD Prediction at MCI Stage by 18F-FDG Brain PET Imaging

    ✓ Peer-reviewed alzhub usefulness score 49 out of 100. IEEE transactions on medical imaging 2020-12-29 Long-term cohort studies

    Alzheimer's Disease (AD), one of the main causes of death in elderly people, is characterized by Mild Cognitive Impairment (MCI) at prodromal stage.

  34. 18F-flortaucipir PET to autopsy comparisons in Alzheimer's disease and other neurodegenerative diseases

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Brain : a journal of neurology 2020-12-01 Brain scans and imaging

    Mean SUVRs were calculated for progressive supranuclear palsy, corticobasal degeneration, and neurofibrillary tangle Braak stage regions of interest, and these values were compared to SUVRs derived from young, non-autopsy, cognitively normal controls used as a standard for tau negativity.

  35. Short-term Psychological Outcomes of Disclosing Amyloid Imaging Results to Research Participants Who Do Not Have Cognitive Impairment

    ✓ Peer-reviewed alzhub usefulness score 74 out of 100. JAMA neurology 2020-12-01 Treatments

    Compared with participants who learned that they had a not elevated amyloid result, individuals who learned of an elevated amyloid result were no more likely to experience short-term increases in depression (mean [SD] change in the Geriatric Depression Scale score, 0.02 [1.3] vs 0.04 [1.3]; P = .90), anxiety (mean [SD] change in State-Trait Anxiety Inventory score, -0.02 [3.2] vs -0.15 [3.0]; P = .65), or suicidality (mean [SD] change in the Columbia Suicide Severity Rating Scale score, 0.0 [0.4] vs -0.01 [0.5]; P = .67).

  36. Evaluation of a visual interpretation method for tau-PET with 18F-flortaucipir

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Alzheimer's & dementia (Amsterdam, Netherlands) 2020-11-28 Brain scans and imaging

    Global visual scores were reliable, correlated with global cortical 18F-flortaucipir standardized uptake value ratio (SUVR) and were associated with clinical diagnosis and amyloid status.

  37. Patient-centered connectivity-based prediction of tau pathology spread in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Science advances 2020-11-27 Brain scans and imaging

    In Alzheimer's disease (AD), the Braak staging scheme suggests a stereotypical tau spreading pattern that does, however, not capture interindividual variability in tau deposition.

  38. Distinct Brain Functional Impairment Patterns Between Suspected Non-Alzheimer Disease Pathophysiology and Alzheimer's Disease: A Study Combining Static and Dynamic Functional Magnetic Resonance Imaging

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Frontiers in aging neuroscience 2020-11-23 Tau biomarkers

    It accounts for a quarter of the elderly population and is associated with cognitive decline.

  39. Accelerated MRI-predicted brain ageing and its associations with cardiometabolic and brain disorders

    ✓ Peer-reviewed alzhub usefulness score 46 out of 100. Scientific reports 2020-11-17 Long-term cohort studies

    Brain structure in later life reflects both influences of intrinsic aging and those of lifestyle, environment and disease.

  40. Defining the Lowest Threshold for Amyloid-PET to Predict Future Cognitive Decline and Amyloid Accumulation

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Neurology 2020-11-16 Biomarkers

    These optimized thresholds can help to inform future research and clinical trials targeting early Aβ.

  41. Amyloid-PET and 18F-FDG-PET in the diagnostic investigation of Alzheimer's disease and other dementias

    ✓ Peer-reviewed alzhub usefulness score 62 out of 100. The Lancet. Neurology 2020-11-01 Getting a diagnosis

    Various biomarkers are available to support the diagnosis of neurodegenerative diseases in clinical and research settings.

  42. Effect of APOE ε4 genotype on amyloid-β and tau accumulation in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. Alzheimer's research & therapy 2020-10-31 Brain scans and imaging

    Progressive tau accumulation may be more prominent in ε4 carriers, particularly in the medial and lateral temporal cortices.

  43. Alzheimer's Disease Detection Through Whole-Brain 3D-CNN MRI

    ✓ Peer-reviewed alzhub usefulness score 51 out of 100. Frontiers in bioengineering and biotechnology 2020-10-30 Digital health tools

    The projected burden of dementia by Alzheimer's disease (AD) represents a looming healthcare crisis as the population of most countries grows older.

  44. EEG microstate complexity for aiding early diagnosis of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 51 out of 100. Scientific reports 2020-10-19 Mild cognitive impairment

    The dynamics of the resting brain exhibit transitions between a small number of discrete networks, each remaining stable for tens to hundreds of milliseconds.

  45. Associations of quantitative susceptibility mapping with Alzheimer's disease clinical and imaging markers

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. NeuroImage 2020-10-06 Brain scans and imaging

    Altered iron metabolism has been hypothesized to be associated with Alzheimer's disease pathology, and prior work has shown associations between iron load and beta amyloid plaques.

  46. Predicting future rates of tau accumulation on PET

    ✓ Peer-reviewed alzhub usefulness score 53 out of 100. Brain : a journal of neurology 2020-10-01 Brain scans and imaging

    In the cognitively unimpaired group, only higher baseline amyloid PET was a significant independent predictor of higher tau accumulation rates (P < 0.001).

  47. Development and evaluation of an automated quantification tool for amyloid PET images

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. EJNMMI physics 2020-09-29 Brain scans and imaging

    Compared with manual step-by-step processing, our developed automated quantification tool reduced processing time by 85%.

  48. Amyloid PET imaging in clinical practice

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Practical neurology 2020-09-24 Brain scans and imaging

    Amyloid positron emission tomography (PET) imaging enables in vivo detection of brain Aβ deposition, one of the neuropathological hallmarks of Alzheimer's disease.

  49. Neuroimaging advances regarding subjective cognitive decline in preclinical Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 62 out of 100. Molecular neurodegeneration 2020-09-22 Digital health tools

    Subjective cognitive decline (SCD) is regarded as the first clinical manifestation in the Alzheimer's disease (AD) continuum.

  50. Classifications of Neurodegenerative Disorders Using a Multiplex Blood Biomarkers-Based Machine Learning Model

    ✓ Peer-reviewed alzhub usefulness score 49 out of 100. International journal of molecular sciences 2020-09-21 Digital health tools

    Easily accessible biomarkers for Alzheimer's disease (AD), Parkinson's disease (PD), frontotemporal dementia (FTD), and related neurodegenerative disorders are urgently needed in an aging society to assist early-stage diagnoses.

From across this tag

7 of the 1,159 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 7. The same 7 appear here every time.

All topic tags with their study counts