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Home › Research › Topics › pet

pet

1,163 studies tagged pet, dated 1983-08-01 to 2026-11-01. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Large-scale head-to-head comparison of on- and off-target profiles of [18F]Tauvid and [18F]MK6240 tau-PET in aging and Alzheimer’s disease 2026-11-01
  2. Detection of tau spatial extent using MK6240 and flortaucipir PET 2026-10-28
  3. Soluble amyloid composition links proximal APP processing, fibrillar burden and the p-tau181 response 2026-10-22

Studies

1,163 studies carry this tag.

Date range

1983 to 2026

Top journals

  • Neurology 88
  • Alzheimer's & dementia : the journal of the Alzheimer's Association 58
  • Brain : a journal of neurology 52
  • Journal of nuclear medicine : official publication, Society of Nuclear Medicine 52
  • Alzheimer's research & therapy 34

337 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Flortaucipir tau PET imaging in semantic variant primary progressive aphasia

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Journal of neurology, neurosurgery, and psychiatry 2017-10-06 Brain scans and imaging

    All seven patients showed elevated FTP uptake in the anterior temporal lobe with a leftward asymmetry that was not observed in healthy controls.

  2. Random Forest Algorithm for the Classification of Neuroimaging Data in Alzheimer's Disease: A Systematic Review

    ✓ Peer-reviewed alzhub usefulness score 68 out of 100. Frontiers in aging neuroscience 2017-10-06 Brain scans and imaging

    Twelve articles-published between the 2007 and 2017-have been included in this systematic review after a quantitative and qualitative selection.

  3. The value of subtraction MRI in detection of amyloid-related imaging abnormalities with oedema or effusion in Alzheimer's patients: An interobserver study

    ✓ Peer-reviewed alzhub usefulness score 69 out of 100. European radiology 2017-09-27 Treatments

    Subtraction MRI has potential as a visual aid increasing the sensitivity of ARIA-E assessment.

  4. Local and distant relationships between amyloid, tau and neurodegeneration in Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. NeuroImage. Clinical 2017-09-25 Brain scans and imaging

    The relationships between β-amyloid (Aβ), tau and neurodegeneration within Alzheimer's Disease pathogenesis are not fully understood.

  5. PET Imaging of Tau Pathology and Relationship to Amyloid, Longitudinal MRI, and Cognitive Change in Down Syndrome: Results from the Down Syndrome Biomarker Initiative (DSBI)

    ✓ Peer-reviewed alzhub usefulness score 53 out of 100. Journal of Alzheimer s Disease 2017-09-18 Brain scans and imaging

    All amyloid negative subjects imaged were tau-negative.

  6. Plasma amyloid β 42/40 ratios as biomarkers for amyloid β cerebral deposition in cognitively normal individuals

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. Alzheimer's & dementia (Amsterdam, Netherlands) 2017-09-12 Biomarkers

    These findings support the use of plasma Aβ42/40 ratios as surrogate biomarkers of cortical Aβ deposition and enrichment tools, reducing the number of subjects submitted to invasive tests and, consequently, recruitment costs in clinical trials targeting cognitively normal individuals.

  7. Correlations of 18F-THK5351 PET with Postmortem Burden of Tau and Astrogliosis in Alzheimer Disease

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2017-09-01 Biomarkers

    Regional in vivo 18 F-THK5351 retention was significantly correlated with the density of tau aggregates in the neocortex and monoamine oxidase-B in the whole brain, but not correlated with that of insoluble amyloid-β.

  8. Distinct 18F-AV-1451 tau PET retention patterns in early- and late-onset Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Brain : a journal of neurology 2017-09-01 Brain scans and imaging

    Patients with Alzheimer's disease can present with different clinical phenotypes.

  9. Sex differences in Alzheimer risk: Brain imaging of endocrine vs chronologic aging

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Neurology 2017-08-30 Brain scans and imaging

    As expected, the MENO group was older than the PERI and CNT groups.

  10. Clinical Use and Utility of Amyloid Imaging

    ✓ Peer-reviewed alzhub usefulness score 44 out of 100. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2017-08-17 Biomarkers

    Currently, 3 amyloid PET tracers are approved and commercially available for clinical use.

  11. Cerebral quantitative susceptibility mapping predicts amyloid-β-related cognitive decline

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Brain : a journal of neurology 2017-08-01 Mild cognitive impairment

    See Derry and Kent (doi:10.1093/awx167) for a scientific commentary on this article.

  12. Imaging plus X: multimodal models of neurodegenerative disease

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. Current opinion in neurology 2017-08-01 Digital health tools

    These models have revealed insights into frontotemporal dementia, Huntington's disease, multiple sclerosis, Parkinson's disease and other conditions.

  13. 18F-Flortaucipir PET/MRI Correlations in Nonamnestic and Amnestic Variants of Alzheimer Disease

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2017-07-26 Brain scans and imaging

    The subgroups showed the expected 18F-flortaucipir-binding patterns.

  14. Presymptomatic atrophy in autosomal dominant Alzheimer's disease: A serial magnetic resonance imaging study

    ✓ Peer-reviewed alzhub usefulness score 51 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2017-07-22 Brain scans and imaging

    Atrophy rates are pathologically increased up to seven years before "expected onset".

  15. Correlation between two methods of florbetapir PET quantitative analysis

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. American journal of nuclear medicine and molecular imaging 2017-07-15 Brain scans and imaging

    This study evaluated performance of a commercially available standardized software program for calculation of florbetapir PET standard uptake value ratios (SUVr) in comparison with an established research method.

  16. Identifying incipient dementia individuals using machine learning and amyloid imaging

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Neurobiology of aging 2017-07-11 Digital health tools

    Identifying individuals destined to develop Alzheimer's dementia within time frames acceptable for clinical trials constitutes an important challenge to design studies to test emerging disease-modifying therapies.

  17. 16S rRNA Next Generation Sequencing Analysis Shows Bacteria in Alzheimer's Post-Mortem Brain

    ✓ Peer-reviewed alzhub usefulness score 49 out of 100. Frontiers in aging neuroscience 2017-06-20 Inflammation and the immune system

    The neurological deterioration associated with Alzheimer's disease (AD), involving accumulation of amyloid-beta peptides and neurofibrillary tangles, is associated with evident neuroinflammation.

  18. Diagnosis of Alzheimer's Disease Based on Structural MRI Images Using a Regularized Extreme Learning Machine and PCA Features

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Journal of healthcare engineering 2017-06-18 Long-term cohort studies

    Alzheimer's disease (AD) is a progressive, neurodegenerative brain disorder that attacks neurotransmitters, brain cells, and nerves, affecting brain functions, memory, and behaviors and then finally causing dementia on elderly people.

  19. Evaluation of Small-Animal PET Outcome Measures to Detect Disease Modification Induced by BACE Inhibition in a Transgenic Mouse Model of Alzheimer Disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2017-06-13 Drug development

    In this study, we investigated the effects of chronic administration of an inhibitor of the β-site amyloid precursor protein-cleaving enzyme 1 (BACE1) on Alzheimer-related pathology by multitracer PET imaging in transgenic APPPS1-21 (TG) mice.

  20. Evaluation of optical coherence tomography angiographic findings in Alzheimer's type dementia

    ✓ Peer-reviewed alzhub usefulness score 49 out of 100. The British journal of ophthalmology 2017-06-09 Cognitive tests and assessment

    Our study included 26 patients in the patient group, and age-matched and sex-matched 26 subjects in the control group.

  21. Functional network integrity presages cognitive decline in preclinical Alzheimer disease

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. Neurology 2017-06-07 Brain scans and imaging

    In clinically normal older adults, lower functional connectivity predicted more rapid decline in PACC scores over time, particularly when coupled with increased Aβ burden.

  22. Association Between Elevated Brain Amyloid and Subsequent Cognitive Decline Among Cognitively Normal Persons

    ✓ Peer-reviewed alzhub usefulness score 73 out of 100. JAMA 2017-06-01 Brain scans and imaging

    Among the 445 participants (243 with normal amyloid, 202 with elevated amyloid), mean (SD) age was 74.0 (5.9) years, mean education was 16.4 (2.7) years, and 52% were women.

  23. EEG spectral analysis as a putative early prognostic biomarker in nondemented, amyloid positive subjects

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Neurobiology of aging 2017-06-01 Mild cognitive impairment

    We studied whether electroencephalography (EEG)-derived measures of brain oscillatory activity are related to clinical progression in nondemented, amyloid positive subjects.

  24. Tau pathology and cognitive reserve in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 46 out of 100. Neurobiology of aging 2017-05-10 Risk factors

    Cognitive reserve (CR) is defined as the ability to maintain functionality despite accumulating pathology.

  25. Primary motor cortex alterations in Alzheimer disease: A study in the 3xTg-AD model

    ✓ Peer-reviewed alzhub usefulness score 34 out of 100. Neurologia 2017-04-19 Biomarkers

    Patients with AD display signs and symptoms of functional impairment from early stages.

  26. Fluorodeoxyglucose metabolism associated with tau-amyloid interaction predicts memory decline

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Annals of neurology 2017-04-06 Brain scans and imaging

    Our study identified a synergistic effect of amyloid and tau deposits and demonstrated, for the first time, in normal elderly its link to AD-like hypometabolism and to AD-like memory decline.

  27. Chemically treated plasma Aβ is a potential blood-based biomarker for screening cerebral amyloid deposition

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Alzheimer's research & therapy 2017-03-22 Biomarkers

    MPP-Aβ might be one of the potential blood biomarkers for the prediction of PiB-PET positivity in the brain.

  28. Feasibility of in vivo 18F-florbetaben PET/MR imaging of human carotid amyloid-β

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. European journal of nuclear medicine and molecular imaging 2017-03-21 Brain scans and imaging

    18F-Florbetaben uptake was clearly visualized in the carotid arteries.

  29. Prediction and classification of Alzheimer disease based on quantification of MRI deformation

    ✓ Peer-reviewed alzhub usefulness score 53 out of 100. PloS one 2017-03-06 Brain scans and imaging

    Detecting early morphological changes in the brain and making early diagnosis are important for Alzheimer's disease (AD).

  30. 18F-AV-1451 positron emission tomography in Alzheimer's disease and progressive supranuclear palsy

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Brain : a journal of neurology 2017-03-01 Brain scans and imaging

    More specifically, 18F-AV-1451 binding was significantly increased in patients with Alzheimer's disease, relative to patients with progressive supranuclear palsy and with control subjects, in the hippocampus and in occipital, parietal, temporal, and frontal cortices (t's > 2.2, P's < 0.04).

  31. Heterogeneity of neuroanatomical patterns in prodromal Alzheimer's disease: links to cognition, progression and biomarkers

    ✓ Peer-reviewed alzhub usefulness score 65 out of 100. Brain : a journal of neurology 2017-03-01 Mild cognitive impairment

    See Coulthard and Knight (doi:10.1093/aww335) for a scientific commentary on this article.

  32. Relationships between flortaucipir PET tau binding and amyloid burden, clinical diagnosis, age and cognition

    ✓ Peer-reviewed alzhub usefulness score 61 out of 100. Brain : a journal of neurology 2017-03-01 Brain scans and imaging

    For amyloid positron emission tomography positive (Aβ+) subjects, flortaucipir neocortical standard uptake value ratio was significantly higher with more advanced clinical stage (Alzheimer's disease > mild cognitive impairment > older cognitively normal) and was significantly elevated for Aβ+ mild cognitive impairment and Alzheimer's disease subjects relative to the respective Aβ- subjects.

  33. Early and late change on the preclinical Alzheimer's cognitive composite in clinically normal older individuals with elevated amyloid β

    ✓ Peer-reviewed alzhub usefulness score 62 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2017-02-28 Brain tissue and pathology

    Sensitive detection of cognitive decline over the course of preclinical Alzheimer's disease is critical as the field moves toward secondary prevention trials.

  34. Tau and β-Amyloid Are Associated with Medial Temporal Lobe Structure, Function, and Memory Encoding in Normal Aging

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. The Journal of neuroscience : the official journal of the Society for Neuroscience 2017-02-17 Brain scans and imaging

    Normal aging is associated with a decline in episodic memory and also with aggregation of the β-amyloid (Aβ) and tau proteins and atrophy of medial temporal lobe (MTL) structures crucial to memory formation.

  35. Association between tau deposition and antecedent amyloid-β accumulation rates in normal and early symptomatic individuals

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Brain 2017-02-15 Brain scans and imaging

    See Vandenberghe and Schaeverbeke (doi:10.1093/awx065) for a scientific commentary on this article.

  36. [Amyloid positron-emission-tomography with [18 F]-florbetaben in the diagnostic workup of dementia patients]

    ✓ Peer-reviewed alzhub usefulness score 46 out of 100. Der Nervenarzt 2017-02 Brain scans and imaging

    17 out of 33 patients were scored as FBB-PET positive.

  37. Diagnostic impact of [18F]flutemetamol PET in early-onset dementia

    ✓ Peer-reviewed alzhub usefulness score 49 out of 100. Alzheimer's research & therapy 2017-01-17 Brain scans and imaging

    [18F]flutemetamol PET scans were positive in 133 out of 211 (63%) patients, of whom 110 out of 144 (76%) patients had a pre-PET Alzheimer's disease (AD) diagnosis and 23 out of 67 (34%) patients had a non-AD diagnosis.

  38. An easy way to increase confidence in beta-amyloid PET evaluation

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Nuclear medicine review. Central & Eastern Europe 2017 Brain scans and imaging

    Early- and late-phase image fusion displayed with appropriate color tables is presented in three different cases to illustrate the added value of the suggested approach.

  39. Cerebrospinal Fluid Aβ42/40 Corresponds Better than Aβ42 to Amyloid PET in Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Journal of Alzheimer's disease : JAD 2017-01-01 Biomarkers

    The CSF Aβ42/40 ratio is superior to Aβ42 alone as a marker of amyloid-positivity by PET.

  40. Depressive Symptoms and Tau Accumulation in the Inferior Temporal Lobe and Entorhinal Cortex in Cognitively Normal Older Adults: A Pilot Study

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Journal of Alzheimer's disease : JAD 2017-01-01 Brain scans and imaging

    Future longitudinal studies examining the association of more severe depressive symptoms and cerebral tau accumulation are needed to substantiate this finding and to guide prevention and treatment in AD.

  41. In vivo Patterns of Tau Pathology, Amyloid-β Burden, and Neuronal Dysfunction in Clinical Variants of Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Journal of Alzheimer's disease : JAD 2017-01-01 Brain scans and imaging

    The clinical heterogeneity of Alzheimer's disease is not reflected in the rather diffuse cortical deposition of amyloid-β.

  42. Optical Coherence Tomography Reveals Retinal Neuroaxonal Thinning in Frontotemporal Dementia as in Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 49 out of 100. Journal of Alzheimer's disease : JAD 2017-01-01 Cognitive tests and assessment

    Alzheimer's disease (AD) and frontotemporal dementia (FTD) are leading causes of cognitive decline.

  43. The Cerebrospinal Fluid Aβ1-42/Aβ1-40 Ratio Improves Concordance with Amyloid-PET for Diagnosing Alzheimer's Disease in a Clinical Setting

    ✓ Peer-reviewed alzhub usefulness score 64 out of 100. Journal of Alzheimer's disease : JAD 2017-01-01 Biomarkers

    We detected an increased concordance in the visual and quantitative (standardized uptake value ratio (SUVR) and total volume of distribution (VT)) [18F]AV45 PET measures when the CSF Aβ1-42/Aβ1-40 was applied compared to Aβ1-42 alone.

  44. AV-1451 tau and β-amyloid positron emission tomography imaging in dementia with Lewy bodies

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. Annals of neurology 2016-12-19 Brain scans and imaging

    Medial temporal lobe AV-1451 uptake distinguishes AD dementia from probable DLB, which may be useful for differential diagnosis.

  45. Rey's Auditory Verbal Learning Test scores can be predicted from whole brain MRI in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. NeuroImage. Clinical 2016-12-18 Digital health tools

    Rey's Auditory Verbal Learning Test (RAVLT) is a powerful neuropsychological tool for testing episodic memory, which is widely used for the cognitive assessment in dementia and pre-dementia conditions.

  46. Post-mortem histopathology underlying β-amyloid PET imaging following flutemetamol F 18 injection

    ✓ Peer-reviewed alzhub usefulness score 44 out of 100. Acta neuropathologica communications 2016-12-12 Brain scans and imaging

    In vivo imaging of fibrillar β-amyloid deposits may assist clinical diagnosis of Alzheimer's disease (AD), aid treatment selection for patients, assist clinical trials of therapeutic drugs through subject selection, and be used as an outcome measure.

  47. Differential diagnosis of mild cognitive impairment and Alzheimer's disease using structural MRI cortical thickness, hippocampal shape, hippocampal texture, and volumetry

    ✓ Peer-reviewed alzhub usefulness score 51 out of 100. NeuroImage. Clinical 2016-12-07 Long-term cohort studies

    This paper presents a brain T1-weighted structural magnetic resonance imaging (MRI) biomarker that combines several individual MRI biomarkers (cortical thickness measurements, volumetric measurements, hippocampal shape, and hippocampal texture).

  48. Assessment of the Incremental Diagnostic Value of Florbetapir F 18 Imaging in Patients With Cognitive Impairment: The Incremental Diagnostic Value of Amyloid PET With [18F]-Florbetapir (INDIA-FBP) Study

    ✓ Peer-reviewed alzhub usefulness score 49 out of 100. JAMA neurology 2016-12-01 Biomarkers

    Diagnostic change occurred in 46 patients (79%) having both a previous diagnosis of AD and an amyloid-negative scan (P Conclusions and relevance Amyloid PET in addition to routine assessment in patients with cognitive impairment has a significant effect on diagnosis, diagnostic confidence, and drug treatment.

  49. Clinical Amyloid Imaging

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Seminars in nuclear medicine 2016-11-24 Biomarkers

    Amyloid plaques, along with neurofibrillary tangles, are a neuropathologic hallmark of Alzheimer disease (AD).

  50. Presymptomatic cortical thinning in familial Alzheimer disease: A longitudinal MRI study

    ✓ Peer-reviewed alzhub usefulness score 62 out of 100. Neurology 2016-10-12 Brain scans and imaging

    The FAD cortical signature appears to be similar to that described for sporadic AD.

From across this tag

10 of the 1,159 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.

All topic tags with their study counts