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hippocampus
499 studies tagged hippocampus, dated 1986-01-01 to 2026-03-31. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Synaptic loss in alcohol use disorder: clinical and mechanistic insights from a PET imaging study 2026-03-31
- Neighborhood environmental deprivation predicts the generalized neurocognitive deficit in schizophrenia 2025-12-19
- Bridging the Gap: Can Hippocampal Sclerosis Serve as a Surrogate Biomarker for LATE‐NC? 2025-12-01
Studies
499 studies carry this tag.
Date range
1986 to 2026
Top journals
- Neurology 38
- Biological psychiatry 36
- NeuroImage 32
- The American journal of psychiatry 22
- Proceedings of the National Academy of Sciences of the United States of America 20
152 journals in all.
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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The association of neurofibrillary tangles with delayed verbal recall may reflect associated hippocampal atrophy.
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Twenty patients with AD and 25 CN subjects had MRI scans and clinical evaluations twice approximately 1.9 years apart.
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Childhood abuse is linked to posttraumatic stress disorder (PTSD), which follows abuse survivors into adulthood.
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Our findings provide new evidence of abnormalities in the hippocampus in early onset depression.
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Animal studies on the effects of chronic variable stress during the peripubertal-juvenile period on hippocampal structure and function are lacking.
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Hypoxia damages multiple organ systems especially those with high oxygen utilization such as the central nervous system.
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Poor memory ability and small hippocampal volume measurements in magnetic resonance images co-occur in neurological patients.
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53/100
Lesions in the hippocampus (HC), the entorhinal cortex (EC), and the prefrontal cortex (PFC) are associated with impairment of episodic memory; reduced HC volume is linked to memory declines in dementia; and decline in EC volume predicts progression from mild cognitive impairment to dementia.
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Acute stress suppresses new cell birth in the hippocampus in several species.
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These results suggest that BD is associated with decreased volumes of medial temporal lobe structures, with greater effect sizes in the amygdala than in the hippocampus.
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Aging is often accompanied by learning and memory problems, many of which resemble deficits associated with hippocampal damage.
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These findings indicate that the prenatal environment can alter behavior, dysregulate neuroendocrine systems, and affect the hippocampal structure of primates in a persistent manner.
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Rates of hippocampal volume loss have been shown to distinguish subjects with dementia of the Alzheimer type (DAT) from nondemented controls.
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These findings suggest that long-term treatment with paroxetine is associated with improvement of verbal declarative memory deficits and an increase in hippocampal volume in PTSD.
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Serial quantitative magnetic resonance imaging (MRI) allows the detection of subtle volumetric changes in brain volume.
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Our recently published data on children investigated within 5 days of a PFC showed that children investigated by MRI within 48 h of a PFC had large hippocampal volumes and prolongation of T2 relaxation time.
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Antidepressants may have a neuroprotective effect during depression.
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MRI studies using the manual tracing method have shown a smaller-than-normal hippocampal volume in patients with posttraumatic stress disorder (PTSD).
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These results are consistent with deficits in hippocampal function and structure in abuse-related PTSD.
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Processing of speech is obligatory. Thus, during normal speech comprehension, the listener is aware of the overall meaning of the speaker's utterance without the need to direct attention to individual linguistic and paralinguistic (intonational, prosodic, etc.) features contained within the speech signal.
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Borderline personality disorder (BPD) is a common disorder associated with emotional dysregulation and other symptoms that have been hypothesized to be related to dysfunction of limbic brain areas including hippocampus and amygdala.
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Twelve patients with refractory temporal lobe epilepsy and unilateral hippocampal sclerosis had repeat volumetric magnetic resonance imaging scans after a mean of 3.4 years to determine whether progressive hippocampal volume loss occurred.
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These findings support the hypothesis of reduced serotonin receptor binding in temporal lobe epileptic foci.
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Several recent studies indicate that activity of cholinergic enzymes in the cortex of people with mild cognitive impairment (MCI) and early Alzheimer's disease (AD) are preserved.
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Studies have examined hippocampal function and volume in depressed subjects, but none have systematically compared never-treated first-episode patients with those who have had multiple episodes.
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High-resolution magnetic resonance microscopy (MRM) was used to determine regional brain volumetric changes in a mouse model of Alzheimer's disease.
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Patients with major depression may have structural abnormalities of the hippocampus that can be detected by analysis of hippocampal shape but not volume.
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Patients with Alzheimer's disease have higher plasma homocysteine levels than controls, but it is uncertain whether higher plasma homocysteine levels are involved in the early pathogenesis of the disease.
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These results suggest that alterations in amygdala:hippocampal volume ratios in pediatric MDD may more reflect severity of associated anxiety than depression.
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The consistency of MRI measurements obtained across sites, and the consistency between the multisite milameline data and that obtained in prior single-site studies, demonstrate the technical feasibility of using structural MRI measures as a surrogate endpoint of disease progression in therapeutic trials.
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Grey matter volume in the posterior hippocampus of London taxi drivers is greater than in age-matched controls, and the size of this increase correlates positively with time spent taxi driving (E.A.
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A smaller hippocampal volume in adult women with major depressive disorder was observed exclusively in those who had a history of severe and prolonged physical and/or sexual abuse in childhood.
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Schizophrenia is associated with structural deformities of the hippocampus, which suggest a disturbance of the connections between the hippocampus and the frontal cortex.
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In animals, exposure to severe stress can damage the hippocampus.
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Because the automatic calculations were faster and less susceptible to rater bias than manual tracing, this automated method is expected to be very useful for analyzing hippocampal changes in studies of aging and dementia.
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These findings suggest that in patients with schizophrenia spectrum disorders, hippocampal volume is influenced in part by schizophrenia susceptibility genes and an interaction of these genes with fetal hypoxia.
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Compared with controls, relatives, particularly from multiplex families, had significantly smaller left hippocampi.
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Hippocampal volume may index disease severity and predict progression in AD.
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These data provide further evidence of structural brain abnormalities in geriatric depression, particularly in patients with a longer course of illness.
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Evidence from neuroimaging studies has suggested areas of the brain that may be damaged by psychological trauma.
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Our results replicate previous findings of reduced hippocampal volume in PTSD but also suggest independent, generalized, white matter atrophy.
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The effect of depression on the hippocampus has become the focus of a number of structural and functional neuroimaging studies.
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The hippocampus is crucial for normal brain function, especially for the encoding and retrieval of multimodal sensory information.
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Postmortem MRI scans were obtained for the first 56 participants of the Nun Study who were scanned.
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This longitudinal quantitative magnetic resonance imaging study of 24 patients with mild temporal lobe epilepsy shows an ipsilateral hippocampal volume decrease of 9% (range, -30 to +0.5%; p = 0.002, paired t test) over a period of 3.5 +/- 0.7 years.
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Recent intriguing reports have shown an association between major depression and selective and persistent loss of hippocampal volume, prompting considerable speculation as to its underlying causes.
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Hypertension is a main risk factor for cerebrovascular disease, including vascular dementia.
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Longitudinally oriented axon collaterals of CA3 pyramidal cells may be critical for integrating distributed information in the hippocampus.
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Intractable epilepsy is related to various transient and chronic brain electric and neurochemical disturbances.
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The results confirmed the correlation between hippocampal volumes and neuron cell counts.
From across this tag
7 of the 499 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 7. The same 7 appear here every time.
- Chronic antidepressant treatment selectively increases expression of plasticity-related proteins in the hippocampus and medial prefrontal cortex of the rat
- Effect of hippocampal and amygdala volumes on clinical outcomes in major depression: a 3-year prospective magnetic resonance imaging study
- Youthful Brains in Older Adults: Preserved Neuroanatomy in the Default Mode and Salience Networks Contributes to Youthful Memory in Superaging
- Hippocampal changes associated with early-life adversity and vulnerability to depression
- Western diet is associated with a smaller hippocampus: a longitudinal investigation
- Association of Neighborhood-Level Disadvantage With Cerebral and Hippocampal Volume
- Physiological and structural evidence for hippocampal involvement in persistent seizure susceptibility after traumatic brain injury