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Comparison of automated and manual MRI volumetry of hippocampus in normal aging and dementia
Hsu YY, Schuff N, Du AT, Mark K, Zhu X, Hardin D, Weiner MW.. Journal of magnetic resonance imaging : JMRI, 2002-09-01
Topic: Risk, prevention and care in population studies
Purpose To determine whether automatic and manual measurements of hippocampal volume differences on MRI between normal aging, cognitive impairment (CI), and Alzheimer's disease (AD) yield similar results. Materials and methods Reliability was determined for an automatic and a manual method on nine volunteers (22-83 years old) who underwent MRI twice in 1 day. Hippocampal volumes of 20 cognitively normal subjects (mean age 74.0 +/- 6.2 years) and age-matched patients (20 CI and 20 AD) were compared. Results The intraclass correlation for automatic calculations of hippocampal volume was 0.94; for manual tracing it was 0.99. Volume differences between cognitively normal, CI, and AD subjects from the automatic and manual methods were similar. Conclusion Because the automatic calculations were faster and less susceptible to rater bias than manual tracing, this automated method is expected to be very useful for analyzing hippocampal changes in studies of aging and dementia.
Key findings
- Purpose To determine whether automatic and manual measurements of hippocampal volume differences on MRI between normal aging, cognitive impairment (CI), and Alzheimer's disease (AD) yield similar results.
- Results The intraclass correlation for automatic calculations of hippocampal volume was 0.94; for manual tracing it was 0.99.
Study details
- Evidence strengthLow
How this study scored 36/100
Published in a peer-reviewed journal. Scored zero for study design, sample size, effect reported, studied in people and randomised / blinded because the record does not state it. We have no data on journal's citation record, times cited, citations per year, impact for its field and year, cited by studies here, still being cited, senior author's track record, institution's track record and multi-centre collaboration, so those were left out: it earned 21 of the 58 points we could judge it on, which is 36 out of 100.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Journal of magnetic resonance imaging : JMRI) |
| Journal's citation record | — / 4 | No journal record from OpenAlex — left out of this score |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 1 / 5 | 2002 — older than 20 years, still counted |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | — / 7 | No citation count (not found in OpenAlex) — left out of this score |
| Citations per year | — / 5 | No citation count or no year — left out of this score |
| Impact for its field and year | — / 6 | No field-weighted citation impact (OpenAlex has none yet) — left out of this score |
| Cited by studies here | — / 6 | Not yet checked against this library's citation graph — left out of this score |
| Still being cited | — / 4 | No yearly citation counts — left out of this score |
| Senior author's track record | — / 4 | Senior author's record not available — left out of this score |
| Institution's track record | — / 3 | No institution listed in OpenAlex — left out of this score |
| Multi-centre collaboration | — / 3 | Institutions not listed — left out of this score |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 12205587) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Points | 21 / 58 | Scored on 11 of 20 parts. We have no data for the rest, so they are left out: 21 of the 58 points we could judge it on is 36 out of 100. |
| Total | 36 / 100 | — |
What each of these 20 components measures, and what this score is not →
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Cite this study APA, Vancouver, BibTeX · download .bib or .ris
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record names 7 authors; APA and Vancouver show the first six, BibTeX and the downloads carry all of them. Check the citation against the original before you use it.
APA 7th
Hsu, Y. Y., Schuff, N., Du, A. T., Mark, K., Zhu, X., Hardin, D., et al. (2002). Comparison of automated and manual MRI volumetry of hippocampus in normal aging and dementia. Journal of magnetic resonance imaging : JMRI. https://doi.org/10.1002/jmri.10163
Vancouver
Hsu YY, Schuff N, Du AT, Mark K, Zhu X, Hardin D, et al. Comparison of automated and manual MRI volumetry of hippocampus in normal aging and dementia. Journal of magnetic resonance imaging : JMRI. 2002. doi:10.1002/jmri.10163. PMID: 12205587.
BibTeX
@article{hsu2002-12205587,
author = {Hsu, Y. Y. and Schuff, N. and Du, A. T. and Mark, K. and Zhu, X. and Hardin, D. and Weiner, M. W.},
title = {{Comparison of automated and manual MRI volumetry of hippocampus in normal aging and dementia}},
journal = {Journal of magnetic resonance imaging : JMRI},
year = {2002},
doi = {10.1002/jmri.10163},
pmid = {12205587},
url = {https://doi.org/10.1002/jmri.10163}
}
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