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The Relationship Between Sleep, Cognition, and Dementia Risk in People With Focal Epilepsy
Xin You Tai, Sijia Zhao, Bernard Liem, Marian Galovic, Masud Husain, Arjune Sen, Sanjay George Manohar. Neurology, 2026-04-22
Topic: Risk, prevention and care in population studies
= 0.991). Optimal sleep modified both cognitive performance and dementia risk in individuals with focal epilepsy compared with stroke patients and healthy controls. Based on self-reported sleep data, these findings suggest that improving sleep may be an impactful intervention to improve cognition and reduce dementia risk particularly in focal epilepsy.
Key findings
- Optimal sleep modified both cognitive performance and dementia risk in individuals with focal epilepsy compared with stroke patients and healthy controls.
- Based on self-reported sleep data, these findings suggest that improving sleep may be an impactful intervention to improve cognition and reduce dementia risk particularly in focal epilepsy.
Why it matters
This cohort study found that optimal sleep modified both cognitive performance and dementia risk in people with focal epilepsy compared with stroke patients and healthy controls. Based on self-reported sleep data, the authors suggest that improving sleep may be an impactful intervention to improve cognition and reduce dementia risk, particularly in focal epilepsy.
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Study details
- Study designcohort study
- Evidence strengthModerate
How this study scored 56/100
Published in a leading specialty journal, and it is a cohort study following people over time. Scored zero for sample size, effect reported, studied in people and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 9 / 10 | Tier 2 — leading specialty journal (Neurology) |
| Journal's citation record | 4 / 4 | Neurology: journal h-index 525 (OpenAlex, 2026-10-29) |
| Study design | 7 / 12 | A cohort study following people over time |
| Strength of evidence | 3 / 5 | Rated “moderate” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 5 / 5 | 2026 — within 1 year(s) of the newest study here |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 1 / 7 | Cited 4 times (OpenAlex, 2026-10-10) |
| Citations per year | 1 / 5 | 2.0 citations a year over 2 year(s) since 2026 |
| Impact for its field and year | 5 / 6 | Cited 33.3× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 1 / 4 | Cited 4 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 2 / 4 | Last-listed author Sanjay Manohar: h-index 41 (OpenAlex, whole career) |
| Institution's track record | 2 / 3 | University of Oxford: institution h-index 2,205 (OpenAlex) |
| Multi-centre collaboration | 2 / 3 | OpenAlex lists 6 institution(s) in 2 countries |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 42018962) |
| Free to read | 2 / 2 | Free to read |
| Total | 56 / 100 | — |
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Read the original
- DOI: 10.1212/wnl.0000000000214985
- PubMed: 42018962
- Original source →
- Free full text: PubMed Central →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record names 7 authors; APA and Vancouver show the first six, BibTeX and the downloads carry all of them. Check the citation against the original before you use it.
APA 7th
Tai, X. Y., Zhao, S., Liem, B., Galovic, M., Husain, M., Sen, A., et al. (2026). The Relationship Between Sleep, Cognition, and Dementia Risk in People With Focal Epilepsy. Neurology. https://doi.org/10.1212/wnl.0000000000214985
Vancouver
Tai XY, Zhao S, Liem B, Galovic M, Husain M, Sen A, et al. The Relationship Between Sleep, Cognition, and Dementia Risk in People With Focal Epilepsy. Neurology. 2026. doi:10.1212/wnl.0000000000214985. PMID: 42018962.
BibTeX
@article{tai2026-42018962,
author = {Tai, Xin You and Zhao, Sijia and Liem, Bernard and Galovic, Marian and Husain, Masud and Sen, Arjune and Manohar, Sanjay George},
title = {{The Relationship Between Sleep, Cognition, and Dementia Risk in People With Focal Epilepsy}},
journal = {Neurology},
year = {2026},
doi = {10.1212/wnl.0000000000214985},
pmid = {42018962},
url = {https://doi.org/10.1212/wnl.0000000000214985}
}
Studies this one cites
Referenced by this study and also in the alzhub library, so you can read them here.