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57/100

✓ Peer-reviewed alzhub usefulness score 57 out of 100. Long-term cohort studies

Topic: Risk, prevention and care in population studies

Background Whether or not there is targeted pharmacotherapy for dementia, an active and healthy lifestyle that includes physical activity (PA) may be a better option than medication for preventing dementia. We examined the association between leisure-time sedentary behavior (SB) and the risk of dementia incidence and mortality. We further quantified the effect on dementia risk of replacing sedentary time with an equal amount of time spent on different physical activities.

Key findings

We examined the association between leisure-time sedentary behavior (SB) and the risk of dementia incidence and mortality.
We further quantified the effect on dementia risk of replacing sedentary time with an equal amount of time spent on different physical activities.
Methods In the UK Biobank, 484,169 participants (mean age = 56.5 years; 45.2% men) free of dementia were followed from baseline (2006-2010) through July 30, 2021.
A standard questionnaire measured individual leisure-time SB (watching TV, computer use, and driving) and PA (walking for pleasure, light and heavy do-it-yourself activity, strenuous sports, and other exercise) frequency and duration in the 4 weeks prior to evaluation.

Why it matters

This study examined the link between leisure-time sedentary behavior and dementia risk, and estimated what happens when sedentary time is replaced with physical activity. It suggests that an active and healthy lifestyle may be a better option than medication for preventing dementia.

Study details

Participants484,169
Effect size45.2%; 82.1%; HR = 1.06
Evidence strengthLow

How this study scored 57/100

Published in a peer-reviewed journal. Scored zero for study design and randomised / blinded because the record does not state it.

Component	Points	Why
Journal tier	7 / 10	Tier 3 — peer-reviewed journal (Journal of sport and health science)
Journal's citation record	1 / 4	Journal of sport and health science/Journal of Sport and Health Science: journal h-index 106 (OpenAlex, 2026-10-29)
Study design	0 / 12	No study design recorded — scores zero, not guessed (not stated in the record — scored 0)
Strength of evidence	1 / 5	Rated “low” in our summary
Peer-review validation	10 / 10	Peer-reviewed. Published as an article in a named peer-reviewed journal.
How recent	3 / 5	2023 — within 6 year(s) of the newest study here
Sample size	4 / 4	484,169 participants
Effect reported	3 / 3	Effect reported with a statistic (interval, p-value, ratio or similar)
Studied in people	3 / 3	Studied in people (participant count stated)
Randomised / blinded	0 / 2	No randomisation or blinding stated — scores zero (not stated in the record — scored 0)
Times cited	4 / 7	Cited 48 times (OpenAlex, 2026-10-10)
Citations per year	3 / 5	9.6 citations a year over 5 year(s) since 2023
Impact for its field and year	3 / 6	Cited 5.5× the average for papers of its field and year (OpenAlex FWCI)
Cited by studies here	2 / 6	Cited by 3 other studies in this library
Still being cited	2 / 4	Cited 41 times in 2024–2026 (2026 still in progress; OpenAlex)
Senior author's track record	2 / 4	Last-listed author Ningjian Wang: h-index 47 (OpenAlex, whole career)
Institution's track record	3 / 3	Harvard University: institution h-index 3,235 (OpenAlex)
Multi-centre collaboration	2 / 3	OpenAlex lists 8 institution(s) in 3 countries
Indexed in PubMed	2 / 2	Indexed in PubMed (PMID 36379419)
Free to read	2 / 2	Free to read
Total	57 / 100	—

What each of these 20 components measures, and what this score is not →

Read the original

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Cite this study APA, Vancouver, BibTeX · download .bib or .ris

Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record's author list ends in “et al.”, so not every author is named. Check the citation against the original before you use it.

APA 7th

Sun, Y., Chen, C., Yu, Y., Zhang, H., Tan, X., Zhang, J., et al. (2023). Replacement of leisure-time sedentary behavior with various physical activities and the risk of dementia incidence and mortality: A prospective cohort study. Journal of sport and health science. https://doi.org/10.1016/j.jshs.2022.11.005

Vancouver

Sun Y, Chen C, Yu Y, Zhang H, Tan X, Zhang J, et al. Replacement of leisure-time sedentary behavior with various physical activities and the risk of dementia incidence and mortality: A prospective cohort study. Journal of sport and health science. 2023. doi:10.1016/j.jshs.2022.11.005. PMID: 36379419.

BibTeX

@article{sun2023-36379419,
  author  = {Sun, Y. and Chen, C. and Yu, Y. and Zhang, H. and Tan, X. and Zhang, J. and Qi, L. and Lu, Y. and others},
  title   = {{Replacement of leisure-time sedentary behavior with various physical activities and the risk of dementia incidence and mortality: A prospective cohort study}},
  journal = {Journal of sport and health science},
  year    = {2023},
  doi     = {10.1016/j.jshs.2022.11.005},
  pmid    = {36379419},
  url     = {https://doi.org/10.1016/j.jshs.2022.11.005}
}

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