Prospective Associations between Single Foods, Alzheimer's Dementia and Memory Decline in the Elderly
Fischer K, Melo van Lent D, Wolfsgruber S, Weinhold L, Kleineidam L, Bickel H, Scherer M, Eisele M et al.. Nutrients, 2018-06-29
Topic: Risk, prevention and care in population studies
Only higher red wine intake was associated with a lower incidence of AD ( HR = 0.92; P = 0.045). Interestingly, this was true only for men ( HR = 0.82; P < 0.001), while in women higher red wine intake was associated with a higher incidence of AD ( HR = 1.15; P = 0.044), and higher white wine intake with a more pronounced memory decline over time ( HR = −0.13; P = 0.052). We found no evidence for these single foods to be protective against cognitive decline, with the exception of red wine, which reduced the risk for AD only in men. Women could be more susceptible to detrimental effects of alcohol.
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APA 7th
Fischer, K., Melo van Lent, D., Wolfsgruber, S., Weinhold, L., Kleineidam, L., Bickel, H., et al. (2018). Prospective Associations between Single Foods, Alzheimer's Dementia and Memory Decline in the Elderly. Nutrients. https://doi.org/10.3390/nu10070852
Vancouver
Fischer K, Melo van Lent D, Wolfsgruber S, Weinhold L, Kleineidam L, Bickel H, et al. Prospective Associations between Single Foods, Alzheimer's Dementia and Memory Decline in the Elderly. Nutrients. 2018. doi:10.3390/nu10070852. PMID: 29966314.
BibTeX
@article{fischer2018-29966314,
author = {Fischer, K. and Melo van Lent, D. and Wolfsgruber, S. and Weinhold, L. and Kleineidam, L. and Bickel, H. and Scherer, M. and Eisele, M. and others},
title = {{Prospective Associations between Single Foods, Alzheimer's Dementia and Memory Decline in the Elderly}},
journal = {Nutrients},
year = {2018},
doi = {10.3390/nu10070852},
pmid = {29966314},
url = {https://doi.org/10.3390/nu10070852}
}
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Key findings
- Only higher red wine intake was associated with a lower incidence of AD ( HR = 0.92; P = 0.045).
- Interestingly, this was true only for men ( HR = 0.82; P < 0.001), while in women higher red wine intake was associated with a higher incidence of AD ( HR = 1.15; P = 0.044), and higher white wine intake with a more pronounced memory decline over time ( HR = −0.13; P = 0.052).
- We found no evidence for these single foods to be protective against cognitive decline, with the exception of red wine, which reduced the risk for AD only in men.
- Women could be more susceptible to detrimental effects of alcohol.
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Study details
- Participants2,622
- Effect sizeHR = 0.92; HR = 0.82; HR = 1.15
- Evidence strengthModerate
How this study scored 61/100
Published in a peer-reviewed journal. Scored zero for study design and randomised / blinded because the record does not state it. We have no data on journal's citation record, times cited, citations per year, impact for its field and year, cited by studies here, still being cited, senior author's track record and institution's track record, so those were left out: it earned 37 of the 61 points we could judge it on, which is 61 out of 100.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Nutrients) |
| Journal's citation record | — / 4 | No journal record from OpenAlex — left out of this score |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 3 / 5 | Rated “moderate” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 2 / 5 | 2018 — within 10 year(s) of the newest study here |
| Sample size | 3 / 4 | 2,622 participants |
| Effect reported | 3 / 3 | Effect reported with a statistic (interval, p-value, ratio or similar) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | — / 7 | No citation count (not found in OpenAlex) — left out of this score |
| Citations per year | — / 5 | No citation count or no year — left out of this score |
| Impact for its field and year | — / 6 | No field-weighted citation impact (OpenAlex has none yet) — left out of this score |
| Cited by studies here | — / 6 | Not yet checked against this library's citation graph — left out of this score |
| Still being cited | — / 4 | No yearly citation counts — left out of this score |
| Senior author's track record | — / 4 | Senior author's record not available — left out of this score |
| Institution's track record | — / 3 | No institution listed in OpenAlex — left out of this score |
| Multi-centre collaboration | 2 / 3 | PubMed indexes it as a multicentre study |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 29966314) |
| Free to read | 2 / 2 | Free to read |
| Points | 37 / 61 | Scored on 12 of 20 parts. We have no data for the rest, so they are left out: 37 of the 61 points we could judge it on is 61 out of 100. |
| Total | 61 / 100 | — |
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