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Post-stroke cognitive impairment and dementia research in Southeast Asia: A scoping review
Memory Lucy Mtambo, T. S. Ragu‐Nathan, Devi Mohan, Narelle Warren, Tin Tin Su, Kia Fatt Quek. Asian Journal of Psychiatry, 2025-03-23
Topic: Risk, prevention and care in population studies
9118 references were identified, and 103 articles (from 78 studies) published between 1992 and 2024 were included. Singapore contributed 42 articles, followed by Indonesia with 28, Malaysia with 17 and Thailand with 15. 35 articles each were from cohort and cross-sectional studies, and 13 were case-control design articles. In Indonesia, the prevalence of post-stroke cognitive impairment (PSCI) ranged from 27.6 % to 81.2 %. In Malaysia, it was between 21.6 % and 76 %; in Singapore, it varied from 12 % to 57.2 %; and in Thailand, between 50.3 % and 55 %. The prevalence of post-troke dementia varied between 2.8 % and 48.4 % in the sources. The most risk factors associated with PSCID included increasing age and low levels of education. Mixed findings on the effectiveness of the limited management strategies for PSCI were reported. The region lacks research from low- and lower-middle-income countries (LLMICs). Moreover, thorough research on how PSCID affects survivors' quality of life (QoL) is deficient. PSCID is common in SEA, requiring urgent interventions for improved QoL for survivors. More research focusing on low- and middle-income countries is needed.
Key findings
- 9118 references were identified, and 103 articles (from 78 studies) published between 1992 and 2024 were included.
- Singapore contributed 42 articles, followed by Indonesia with 28, Malaysia with 17 and Thailand with 15. 35 articles each were from cohort and cross-sectional studies, and 13 were case-control design articles.
- In Indonesia, the prevalence of post-stroke cognitive impairment (PSCI) ranged from 27.6 % to 81.2 %.
- In Malaysia, it was between 21.6 % and 76 %; in Singapore, it varied from 12 % to 57.2 %; and in Thailand, between 50.3 % and 55 %.
- The prevalence of post-troke dementia varied between 2.8 % and 48.4 % in the sources.
Why it matters
This review found that post-stroke cognitive impairment and dementia are common in Southeast Asia, with prevalence varying widely across countries. It also found limited and mixed evidence on management strategies, and a lack of research from low- and lower-middle-income countries.
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Study details
- Study designcase-control study
- Evidence strengthModerate
How this study scored 53/100
Published in a peer-reviewed journal, and it is a case-control study. Scored zero for sample size, effect reported, studied in people and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Asian Journal of Psychiatry) |
| Journal's citation record | 1 / 4 | Asian Journal of Psychiatry: journal h-index 98 (OpenAlex, 2026-10-29) |
| Study design | 6 / 12 | A case-control study |
| Strength of evidence | 3 / 5 | Rated “moderate” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 4 / 5 | 2025 — within 3 year(s) of the newest study here |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 3 / 7 | Cited 16 times (OpenAlex, 2026-10-10) |
| Citations per year | 2 / 5 | 5.3 citations a year over 3 year(s) since 2025 |
| Impact for its field and year | 4 / 6 | Cited 10.2× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 1 / 6 | Cited by 1 other studies in this library |
| Still being cited | 2 / 4 | Cited 16 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 2 / 4 | Last-listed author Kia Fatt Quek: h-index 26 (OpenAlex, whole career) |
| Institution's track record | 2 / 3 | The University of Queensland: institution h-index 1,516 (OpenAlex) |
| Multi-centre collaboration | 2 / 3 | OpenAlex lists 5 institution(s) in 3 countries |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 40157215) |
| Free to read | 2 / 2 | Free to read |
| Total | 53 / 100 | — |
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Read the original
- DOI: 10.1016/j.ajp.2025.104460
- PubMed: 40157215
- Original source →
- Free full text: Asian Journal of Psychiatry →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. Check the citation against the original before you use it.
APA 7th
Mtambo, M. L., Ragu‐Nathan, T. S., Mohan, D., Warren, N., Su, T. T., & Quek, K. F. (2025). Post-stroke cognitive impairment and dementia research in Southeast Asia: A scoping review. Asian Journal of Psychiatry. https://doi.org/10.1016/j.ajp.2025.104460
Vancouver
Mtambo ML, Ragu‐Nathan TS, Mohan D, Warren N, Su TT, Quek KF. Post-stroke cognitive impairment and dementia research in Southeast Asia: A scoping review. Asian Journal of Psychiatry. 2025. doi:10.1016/j.ajp.2025.104460. PMID: 40157215.
BibTeX
@article{mtambo2025-40157215,
author = {Mtambo, Memory Lucy and Ragu‐Nathan, T. S. and Mohan, Devi and Warren, Narelle and Su, Tin Tin and Quek, Kia Fatt},
title = {{Post-stroke cognitive impairment and dementia research in Southeast Asia: A scoping review}},
journal = {Asian Journal of Psychiatry},
year = {2025},
doi = {10.1016/j.ajp.2025.104460},
pmid = {40157215},
url = {https://doi.org/10.1016/j.ajp.2025.104460}
}
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