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Perceived Control, Cognitive Training, and Incident Alzheimer’s Disease and Related Dementias in the ACTIVE Study
Laura B. Zahodne, Katherine E. M. Miller, Chuxuan Sun, Neika Sharifian, Jeanine M. Parisi, George W. Rebok, Adrienne T. Aiken‐Morgan, Alden L. Gross et al.. The Journals of Gerontology Series B, 2025-04-30
Topic: Risk, prevention and care in population studies
Greater perceived control at study baseline was associated with reduced hazard of ADRD. Perceived control did not moderate associations between intervention group and time to ADRD diagnosis. Strengthening perceived control through individual and/or environmental interventions may lower ADRD risk.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Zahodne, L. B., Miller, K. E. M., Sun, C., Sharifian, N., Parisi, J. M., Rebok, G. W., et al. (2025). Perceived Control, Cognitive Training, and Incident Alzheimer’s Disease and Related Dementias in the ACTIVE Study. The Journals of Gerontology Series B. https://doi.org/10.1093/geronb/gbaf086
Vancouver
Zahodne LB, Miller KEM, Sun C, Sharifian N, Parisi JM, Rebok GW, et al. Perceived Control, Cognitive Training, and Incident Alzheimer’s Disease and Related Dementias in the ACTIVE Study. The Journals of Gerontology Series B. 2025. doi:10.1093/geronb/gbaf086. PMID: 40326605.
BibTeX
@article{zahodne2025-40326605,
author = {Zahodne, Laura B. and Miller, Katherine E. M. and Sun, Chuxuan and Sharifian, Neika and Parisi, Jeanine M. and Rebok, George W. and Aiken‐Morgan, Adrienne T. and Gross, Alden L. and others},
title = {{Perceived Control, Cognitive Training, and Incident Alzheimer’s Disease and Related Dementias in the ACTIVE Study}},
journal = {The Journals of Gerontology Series B},
year = {2025},
doi = {10.1093/geronb/gbaf086},
pmid = {40326605},
url = {https://doi.org/10.1093/geronb/gbaf086}
}
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Key findings
- Greater perceived control at study baseline was associated with reduced hazard of ADRD.
- Perceived control did not moderate associations between intervention group and time to ADRD diagnosis.
- Strengthening perceived control through individual and/or environmental interventions may lower ADRD risk.
Why it matters
In the ACTIVE study, greater perceived control at baseline was linked to lower risk of Alzheimer's disease and related dementias, but perceived control did not change the relationship between the training intervention and time to diagnosis. Strengthening perceived control through individual or environmental interventions may lower dementia risk.
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Study details
- Participants2,021
- Evidence strengthLow
How this study scored 42/100
Published in a peer-reviewed journal. Scored zero for study design, effect reported and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (The Journals of Gerontology Series B) |
| Journal's citation record | 2 / 4 | The Journals of Gerontology Series B: journal h-index 225 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 4 / 5 | 2025 — within 3 year(s) of the newest study here |
| Sample size | 3 / 4 | 2,021 participants |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 1 / 7 | Cited 1 times (OpenAlex, 2026-10-10) |
| Citations per year | 0 / 5 | 0.3 citations a year over 3 year(s) since 2025 |
| Impact for its field and year | 1 / 6 | Cited 0.6× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 0 / 4 | Cited 1 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 2 / 4 | Last-listed author Norma B. Coe: h-index 31 (OpenAlex, whole career) |
| Institution's track record | 2 / 3 | Johns Hopkins University: institution h-index 2,306 (OpenAlex) |
| Multi-centre collaboration | 2 / 3 | OpenAlex lists 7 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 40326605) |
| Free to read | 2 / 2 | Free to read |
| Total | 42 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
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Studies this one cites
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