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The Validity and Reliability of the Mini-Mental State Examination-2 for Detecting Vascular Mild Cognitive Impairment and Vascular Dementia in a Korean Population
Min Jae Baek, Young Ho Park, SangYun Kim. Journal of Korean Medical Science, 2025-01-01
Topic: Risk, prevention and care in population studies
The MMSE-2 demonstrated robust performance in differentiating participants across Clinical Dementia Rating (CDR) stages and CDR-Sum of Boxes scores. It exhibited excellent internal consistency, high test-retest reliability, and strong interrater reliability. Concurrent validity with the original MMSE and other neuropsychological measures was also high. The MMSE-2 showed relatively high sensitivity and specificity in distinguishing normal cognitive aging, VaMCI, and VD. The MMSE-2 is a valid and reliable tool for assessing cognitive impairment in patients with VCI in a Korean population. While its specificity in differentiating VaMCI from healthy aging remains relatively modest, the MMSE-2 demonstrates superior sensitivity in detecting VaMCI compared to the original MMSE. These findings suggest that the MMSE-2 is a valuable screening instrument for identifying early cognitive changes associated with VCI.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Baek, M. J., Park, Y. H., & Kim, S. (2025). The Validity and Reliability of the Mini-Mental State Examination-2 for Detecting Vascular Mild Cognitive Impairment and Vascular Dementia in a Korean Population. Journal of Korean Medical Science. https://doi.org/10.3346/jkms.2025.40.e207
Vancouver
Baek MJ, Park YH, Kim S. The Validity and Reliability of the Mini-Mental State Examination-2 for Detecting Vascular Mild Cognitive Impairment and Vascular Dementia in a Korean Population. Journal of Korean Medical Science. 2025. doi:10.3346/jkms.2025.40.e207. PMID: 40827323.
BibTeX
@article{baek2025-40827323,
author = {Baek, Min Jae and Park, Young Ho and Kim, SangYun},
title = {{The Validity and Reliability of the Mini-Mental State Examination-2 for Detecting Vascular Mild Cognitive Impairment and Vascular Dementia in a Korean Population}},
journal = {Journal of Korean Medical Science},
year = {2025},
doi = {10.3346/jkms.2025.40.e207},
pmid = {40827323},
url = {https://doi.org/10.3346/jkms.2025.40.e207}
}
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. Check the citation against the original before you use it.
Key findings
- The MMSE-2 demonstrated robust performance in differentiating participants across Clinical Dementia Rating (CDR) stages and CDR-Sum of Boxes scores.
- It exhibited excellent internal consistency, high test-retest reliability, and strong interrater reliability.
- Concurrent validity with the original MMSE and other neuropsychological measures was also high.
- The MMSE-2 showed relatively high sensitivity and specificity in distinguishing normal cognitive aging, VaMCI, and VD.
- The MMSE-2 is a valid and reliable tool for assessing cognitive impairment in patients with VCI in a Korean population.
Why it matters
The MMSE-2 was found to be a valid and reliable tool for detecting vascular mild cognitive impairment and vascular dementia in a Korean population. This is a screening tool and does not provide a treatment, cure, or prevention for Alzheimer's disease.
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Study details
- Participants66
- Evidence strengthLow
How this study scored 41/100
Published in a peer-reviewed journal. Scored zero for study design, effect reported and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Journal of Korean Medical Science) |
| Journal's citation record | 1 / 4 | Journal of Korean Medical Science: journal h-index 111 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 4 / 5 | 2025 — within 3 year(s) of the newest study here |
| Sample size | 1 / 4 | 66 participants |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 1 / 7 | Cited 4 times (OpenAlex, 2026-10-10) |
| Citations per year | 1 / 5 | 1.3 citations a year over 3 year(s) since 2025 |
| Impact for its field and year | 2 / 6 | Cited 2.5× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 1 / 4 | Cited 4 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 3 / 4 | Last-listed author SangYun Kim: h-index 53 (OpenAlex, whole career) |
| Institution's track record | 1 / 3 | Seoul National University: institution h-index 1,053 (OpenAlex) |
| Multi-centre collaboration | 1 / 3 | OpenAlex lists 2 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 40827323) |
| Free to read | 2 / 2 | Free to read |
| Total | 41 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
- DOI: 10.3346/jkms.2025.40.e207
- PubMed: 40827323
- Original source →
- Free full text: Journal of Korean Medical Science →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
Studies this one cites
Referenced by this study and also in the alzhub library, so you can read them here.
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