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Mild cognitive impairment with subcortical vascular features: clinical characteristics and outcome
Frisoni GB, Frisoni GB, Galluzzi S, Bresciani L, Zanetti O, Geroldi C.. Journal of neurology, 2002-10-01
Topic: Risk, prevention and care in population studies
Objectives To identify non-demented individuals with cognitive impairment due to a cerebrovascular etiology among those coming to observation of a memory clinic and to describe their clinical features and outcome. Methods Patients were enrolled in a prospective study on early cognitive impairment carried out in a Memory Clinic. Mild cognitive impairment of the vascular type (MCI-V) was defined based on modified criteria for subcortical vascular dementia (SVD) by Erkinjuntti and colleagues.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Frisoni, G. B., Galluzzi, S., Bresciani, L., Zanetti, O., & Geroldi, C. (2002). Mild cognitive impairment with subcortical vascular features: clinical characteristics and outcome. Journal of neurology. https://doi.org/10.1007/s00415-002-0861-7
Vancouver
Frisoni GB, Galluzzi S, Bresciani L, Zanetti O, Geroldi C. Mild cognitive impairment with subcortical vascular features: clinical characteristics and outcome. Journal of neurology. 2002. doi:10.1007/s00415-002-0861-7. PMID: 12382161.
BibTeX
@article{frisoni2002-12382161,
author = {Frisoni, G. B. and Galluzzi, S. and Bresciani, L. and Zanetti, O. and Geroldi, C.},
title = {{Mild cognitive impairment with subcortical vascular features: clinical characteristics and outcome}},
journal = {Journal of neurology},
year = {2002},
doi = {10.1007/s00415-002-0861-7},
pmid = {12382161},
url = {https://doi.org/10.1007/s00415-002-0861-7}
}
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Key findings
- Methods Patients were enrolled in a prospective study on early cognitive impairment carried out in a Memory Clinic.
- Mild cognitive impairment of the vascular type (MCI-V) was defined based on modified criteria for subcortical vascular dementia (SVD) by Erkinjuntti and colleagues.
- Twenty-nine patients with MCI-V (age 78 +/- 7, Mini Mental State Exam (MMSE) 24 +/- 3) were compared with 14 with mild cognitive impairment of degenerative etiology (MCI) based on the Mayo Clinic criteria (age 72 +/- 9, MMSE 25 +/- 2), and to 21 patients with frank SVD (age 80 +/- 6, MMSE 21 +/- 3).
- Patients were followed over time for 32 +/- 8 months.
Why it matters
This study described 29 patients with mild cognitive impairment thought to be caused by blood vessel problems in the brain, comparing them with 14 patients whose impairment had a degenerative cause. It aimed to define this vascular type of mild cognitive impairment and describe how it progresses, which could help identify it earlier.
Study details
- Participants21
- Evidence strengthLow
How this study scored 42/100
Published in a peer-reviewed journal. Scored zero for study design, effect reported and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Journal of neurology) |
| Journal's citation record | 2 / 4 | Journal of Neurology: journal h-index 208 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 1 / 5 | 2002 — older than 20 years, still counted |
| Sample size | 1 / 4 | 21 participants |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 5 / 7 | Cited 163 times (OpenAlex, 2026-10-10) |
| Citations per year | 2 / 5 | 6.3 citations a year over 26 year(s) since 2002 |
| Impact for its field and year | 3 / 6 | Cited 4.7× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 2 / 6 | Cited by 4 other studies in this library |
| Still being cited | 1 / 4 | Cited 5 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 2 / 4 | Last-listed author Cristina Geroldi: h-index 49 (OpenAlex, whole career) |
| Institution's track record | 0 / 3 | Centro San Giovanni di Dio Fatebenefratelli: institution h-index 282 (OpenAlex) |
| Multi-centre collaboration | 0 / 3 | OpenAlex lists 1 institution(s) in 1 country — scores zero (affiliation lists can be incomplete) |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 12382161) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Total | 42 / 100 | — |
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