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Incidence of and risk factors for Alzheimer's disease and mild cognitive impairment in Korean elderly
Bae JB, Kim YJ, Han JW, Kim TH, Park JH, Lee SB, Lee JJ, Jeong HG et al.. Dementia and geriatric cognitive disorders, 2014-11-11
Topic: Amyloid, tau and blood-test diagnosis
Background/aims Knowledge of incidence rates and risk factors is essential for the development of strategies to treat patients with Alzheimer's disease (AD) and mild cognitive impairment (MCI). Methods A subpopulation of the Nationwide Survey on Dementia Epidemiology (460 Korean subjects aged ≥65 years from 2 rural and 2 urban districts) was followed up for 3.5 years. The age-specific incidence was estimated and risk factors were identified. Results The age-standardized incidence of AD and MCI was 7.9 and 28.1 cases per 1,000 person-years, respectively. MCI was associated with a 6-fold increased risk of AD. Depression was a risk factor for AD with MCI. Age, lack of formal education, illiteracy, rural residence, and marital status were associated with the risk of AD. Conclusion Strategies to control modifiable risk factors should be implemented to decrease the incidence of AD.
Key findings
- Results The age-standardized incidence of AD and MCI was 7.9 and 28.1 cases per 1,000 person-years, respectively.
- MCI was associated with a 6-fold increased risk of AD.
- Age, lack of formal education, illiteracy, rural residence, and marital status were associated with the risk of AD.
Why it matters
This follow-up of Korean older adults estimated the incidence of Alzheimer's disease and mild cognitive impairment, and found that mild cognitive impairment was associated with a 6-fold increased risk of Alzheimer's disease. It also identified age, lack of formal education, illiteracy, rural residence and marital status as associated with Alzheimer's disease risk.
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Study details
- Effect sizeor 3.5
- Evidence strengthLow
How this study scored 43/100
Published in a peer-reviewed journal. Scored zero for study design, sample size, studied in people and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Dementia and geriatric cognitive disorders) |
| Journal's citation record | 1 / 4 | Dementia and Geriatric Cognitive Disorders: journal h-index 149 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 1 / 5 | 2015 — within 20 year(s) of the newest study here |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 2 / 3 | Effect reported as a number, without an interval or test |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 5 / 7 | Cited 103 times (OpenAlex, 2026-10-10) |
| Citations per year | 2 / 5 | 7.9 citations a year over 13 year(s) since 2015 |
| Impact for its field and year | 3 / 6 | Cited 3.2× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 1 / 6 | Cited by 2 other studies in this library |
| Still being cited | 2 / 4 | Cited 18 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 3 / 4 | Last-listed author Ki Woong Kim: h-index 69 (OpenAlex, whole career) |
| Institution's track record | 1 / 3 | Seoul National University: institution h-index 1,053 (OpenAlex) |
| Multi-centre collaboration | 2 / 3 | OpenAlex lists 8 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 25401488) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Total | 43 / 100 | — |
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Read the original
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Cite this study APA, Vancouver, BibTeX · download .bib or .ris
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record's author list ends in “et al.”, so not every author is named. Check the citation against the original before you use it.
APA 7th
Bae, J. B., Kim, Y. J., Han, J. W., Kim, T. H., Park, J. H., Lee, S. B., et al. (2015). Incidence of and risk factors for Alzheimer's disease and mild cognitive impairment in Korean elderly. Dementia and geriatric cognitive disorders. https://doi.org/10.1159/000366555
Vancouver
Bae JB, Kim YJ, Han JW, Kim TH, Park JH, Lee SB, et al. Incidence of and risk factors for Alzheimer's disease and mild cognitive impairment in Korean elderly. Dementia and geriatric cognitive disorders. 2015. doi:10.1159/000366555. PMID: 25401488.
BibTeX
@article{bae2015-25401488,
author = {Bae, J. B. and Kim, Y. J. and Han, J. W. and Kim, T. H. and Park, J. H. and Lee, S. B. and Lee, J. J. and Jeong, H. G. and others},
title = {{Incidence of and risk factors for Alzheimer's disease and mild cognitive impairment in Korean elderly}},
journal = {Dementia and geriatric cognitive disorders},
year = {2015},
doi = {10.1159/000366555},
pmid = {25401488},
url = {https://doi.org/10.1159/000366555}
}
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