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Cortical microinfarcts on 3T MRI: Clinical correlates in memory-clinic patients
van Veluw SJ, Hilal S, Kuijf HJ, Ikram MK, Xin X, Yeow TB, Venketasubramanian N, Biessels GJ et al.. Alzheimer's & dementia : the journal of the Alzheimer's Association, 2015-05-05
Topic: Brain proteins, microglia and lab models
Introduction This is the first study to assess cerebral microinfarcts (CMIs) on 3 tesla (3T) magnetic resonance imaging (MRI) in a memory clinic population. Methods We included 238 consecutive patients (aged 72.5 ± 9.1 years) from a memory clinic in Singapore. All patients underwent extensive neurological and neuropsychological testing and 3T MRI on the same day.
Key findings
- Methods We included 238 consecutive patients (aged 72.5 ± 9.1 years) from a memory clinic in Singapore.
- All patients underwent extensive neurological and neuropsychological testing and 3T MRI on the same day.
- Cortical CMI rating criteria were adapted from a previous study on 7T MRI.
- We analyzed the frequency and association of cortical CMIs with demographic, clinical, cognition, and other MRI findings.
Why it matters
This study assessed cerebral microinfarcts on 3 tesla MRI in 238 memory clinic patients in Singapore. The available text does not report how these microinfarcts related to cognition or diagnosis.
Study details
- Participants238
- Evidence strengthLow
How this study scored 52/100
Published in a leading specialty journal. Scored zero for study design, effect reported and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 9 / 10 | Tier 2 — leading specialty journal (Alzheimer's & dementia : the journal of the Alzheimer's Association) |
| Journal's citation record | 2 / 4 | Alzheimer s & Dementia: journal h-index 228 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 1 / 5 | 2015 — within 20 year(s) of the newest study here |
| Sample size | 2 / 4 | 238 participants |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 5 / 7 | Cited 142 times (OpenAlex, 2026-10-10) |
| Citations per year | 3 / 5 | 10.9 citations a year over 13 year(s) since 2015 |
| Impact for its field and year | 4 / 6 | Cited 11.6× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 2 / 6 | Cited by 6 other studies in this library |
| Still being cited | 2 / 4 | Cited 24 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 3 / 4 | Last-listed author Christopher Chen: h-index 90 (OpenAlex, whole career) |
| Institution's track record | 1 / 3 | National University of Singapore: institution h-index 1,166 (OpenAlex) |
| Multi-centre collaboration | 2 / 3 | OpenAlex lists 5 institution(s) in 2 countries |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 25956990) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Total | 52 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
- DOI: 10.1016/j.jalz.2014.12.010
- PubMed: 25956990
- Original source →
- Free full text: Utrecht University Repository (Utrecht University) →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record's author list ends in “et al.”, so not every author is named. Check the citation against the original before you use it.
APA 7th
van Veluw, S. J., Hilal, S., Kuijf, H. J., Ikram, M. K., Xin, X., Yeow, T. B., et al. (2015). Cortical microinfarcts on 3T MRI: Clinical correlates in memory-clinic patients. Alzheimer's & dementia : the journal of the Alzheimer's Association. https://doi.org/10.1016/j.jalz.2014.12.010
Vancouver
van Veluw SJ, Hilal S, Kuijf HJ, Ikram MK, Xin X, Yeow TB, et al. Cortical microinfarcts on 3T MRI: Clinical correlates in memory-clinic patients. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2015. doi:10.1016/j.jalz.2014.12.010. PMID: 25956990.
BibTeX
@article{vanveluw2015-25956990,
author = {van Veluw, S. J. and Hilal, S. and Kuijf, H. J. and Ikram, M. K. and Xin, X. and Yeow, T. B. and Venketasubramanian, N. and Biessels, G. J. and others},
title = {{Cortical microinfarcts on 3T MRI: Clinical correlates in memory-clinic patients}},
journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
year = {2015},
doi = {10.1016/j.jalz.2014.12.010},
pmid = {25956990},
url = {https://doi.org/10.1016/j.jalz.2014.12.010}
}
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