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Biomarker-based prognosis for people with mild cognitive impairment (ABIDE): a modelling study
van Maurik IS, Vos SJ, Bos I, Bouwman FH, Teunissen CE, Scheltens P, Barkhof F, Frolich L et al.. The Lancet. Neurology, 2019-09-13
Topic: Risk, prevention and care in population studies
The models could aid clinicians in the interpretation of CSF biomarker and hippocampal volume results in individuals with MCI, and help research and clinical settings to prepare for a future of precision medicine in Alzheimer's disease.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
van Maurik, I. S., Vos, S. J., Bos, I., Bouwman, F. H., Teunissen, C. E., Scheltens, P., et al. (2019). Biomarker-based prognosis for people with mild cognitive impairment (ABIDE): a modelling study. The Lancet. Neurology. https://doi.org/10.1016/s1474-4422(19)30283-2
Vancouver
van Maurik IS, Vos SJ, Bos I, Bouwman FH, Teunissen CE, Scheltens P, et al. Biomarker-based prognosis for people with mild cognitive impairment (ABIDE): a modelling study. The Lancet. Neurology. 2019. doi:10.1016/s1474-4422(19)30283-2. PMID: 31526625.
BibTeX
@article{vanmaurik2019-31526625,
author = {van Maurik, I. S. and Vos, S. J. and Bos, I. and Bouwman, F. H. and Teunissen, C. E. and Scheltens, P. and Barkhof, F. and Frolich, L. and others},
title = {{Biomarker-based prognosis for people with mild cognitive impairment (ABIDE): a modelling study}},
journal = {The Lancet. Neurology},
year = {2019},
doi = {10.1016/s1474-4422(19)30283-2},
pmid = {31526625},
url = {https://doi.org/10.1016/s1474-4422(19)30283-2}
}
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record's author list ends in “et al.”, so not every author is named. Check the citation against the original before you use it.
Key findings
- The models could aid clinicians in the interpretation of CSF biomarker and hippocampal volume results in individuals with MCI, and help research and clinical settings to prepare for a future of precision medicine in Alzheimer's disease.
Why it matters
This modelling study suggests that combining CSF biomarker and hippocampal volume results could help clinicians interpret test results in people with mild cognitive impairment. It is about improving prognosis and preparing for precision medicine, not about a treatment, cure or prevention.
Study details
- Participants883
- Evidence strengthModerate
How this study scored 60/100
Published in a leading specialty journal. Scored zero for study design, effect reported and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 9 / 10 | Tier 2 — leading specialty journal (The Lancet. Neurology) |
| Journal's citation record | 3 / 4 | The Lancet Neurology: journal h-index 457 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 3 / 5 | Rated “moderate” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 2 / 5 | 2019 — within 10 year(s) of the newest study here |
| Sample size | 2 / 4 | 883 participants |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 5 / 7 | Cited 128 times (OpenAlex, 2026-10-10) |
| Citations per year | 3 / 5 | 14.2 citations a year over 9 year(s) since 2019 |
| Impact for its field and year | 4 / 6 | Cited 10.5× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 3 / 6 | Cited by 14 other studies in this library |
| Still being cited | 2 / 4 | Cited 40 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 4 / 4 | Last-listed author Wiesje M. van der Flier: h-index 132 (OpenAlex, whole career) |
| Institution's track record | 2 / 3 | University of Oxford: institution h-index 2,205 (OpenAlex) |
| Multi-centre collaboration | 3 / 3 | OpenAlex lists 52 institution(s) in 13 countries |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 31526625) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Total | 60 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
- DOI: 10.1016/s1474-4422(19)30283-2
- PubMed: 31526625
- Original source →
- Free full text: The Lancet Neurology →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
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