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Attention Networks Connectivity After Cognitive Rehabilitation in Alzheimer’s Disease
Éric Salmon, Mohamed Ali Bahri, Sophie Kurth, Fabienne Collette, Christophe L. M. Phillips, Steve Majerus, Françoise Lekeu, Anne Quittre et al.. Journal of Geriatric Psychiatry and Neurology, 2026-06-17
Topic: Amyloid, tau and blood-test diagnosis
Introduction Cognitive rehabilitation (CR) enhances the autonomy of patients with Alzheimer’s disease. Their daily activities are likely dependent on attention networks. Method This pilot resting-state fMRI study investigated the cerebral correlates of CR in participants with mild Alzheimer disease (n = 22), compared to a control intervention in patients (n = 21) and in healthy participants (n = 27). Connectivity changes between dorsal and ventral attention networks were expected after 3 months of rehabilitation. Results A mixed ANOVA comparing pre- and post-intervention data across groups revealed increased connectivity between the dorsal and the ventral attention network following CR (FDR-corrected P = .0072). A post hoc correlation analysis of post-intervention data in the CR group showed that greater autonomy in daily activities was associated with stronger functional relationship between the two attention networks (FDR-corrected P = .0001). Conclusion Enhanced connectivity between attention networks may be a characteristic of CR benefits in individuals with mild Alzheimer disease.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Salmon, É., Bahri, M. A., Kurth, S., Collette, F., Phillips, C. L. M., Majerus, S., et al. (2026). Attention Networks Connectivity After Cognitive Rehabilitation in Alzheimer’s Disease. Journal of Geriatric Psychiatry and Neurology. https://doi.org/10.1177/08919887261462178
Vancouver
Salmon É, Bahri MA, Kurth S, Collette F, Phillips CLM, Majerus S, et al. Attention Networks Connectivity After Cognitive Rehabilitation in Alzheimer’s Disease. Journal of Geriatric Psychiatry and Neurology. 2026. doi:10.1177/08919887261462178. PMID: 42308323.
BibTeX
@article{salmon2026-42308323,
author = {Salmon, Éric and Bahri, Mohamed Ali and Kurth, Sophie and Collette, Fabienne and Phillips, Christophe L. M. and Majerus, Steve and Lekeu, Françoise and Quittre, Anne and others},
title = {{Attention Networks Connectivity After Cognitive Rehabilitation in Alzheimer’s Disease}},
journal = {Journal of Geriatric Psychiatry and Neurology},
year = {2026},
doi = {10.1177/08919887261462178},
pmid = {42308323},
url = {https://doi.org/10.1177/08919887261462178}
}
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Key findings
- Method This pilot resting-state fMRI study investigated the cerebral correlates of CR in participants with mild Alzheimer disease (n = 22), compared to a control intervention in patients (n = 21) and in healthy participants (n = 27).
- Results A mixed ANOVA comparing pre- and post-intervention data across groups revealed increased connectivity between the dorsal and the ventral attention network following CR (FDR-corrected P = .0072).
- A post hoc correlation analysis of post-intervention data in the CR group showed that greater autonomy in daily activities was associated with stronger functional relationship between the two attention networks (FDR-corrected P = .0001).
Why it matters
In this pilot resting-state fMRI study, cognitive rehabilitation in people with mild Alzheimer's disease was followed by increased connectivity between the dorsal and ventral attention networks, and greater autonomy in daily activities was associated with stronger connectivity between these networks. The authors conclude that enhanced connectivity between attention networks may be a characteristic of cognitive rehabilitation benefits, but this is a pilot study and does not show a cure or prevention.
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Study details
- Participants22
- Evidence strengthLow
How this study scored 34/100
Published in a peer-reviewed journal. Scored zero for study design, effect reported and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Journal of Geriatric Psychiatry and Neurology) |
| Journal's citation record | 1 / 4 | Journal of Geriatric Psychiatry and Neurology: journal h-index 105 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 5 / 5 | 2026 — within 1 year(s) of the newest study here |
| Sample size | 1 / 4 | 22 participants |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 0 / 7 | Cited 0 times (OpenAlex, 2026-10-10) |
| Citations per year | 0 / 5 | 0.0 citations a year over 2 year(s) since 2026 |
| Impact for its field and year | 0 / 6 | Cited 0.0× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 0 / 4 | Cited 0 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 2 / 4 | Last-listed author Christine Bastin: h-index 35 (OpenAlex, whole career) |
| Institution's track record | 1 / 3 | University of Liège: institution h-index 901 (OpenAlex) |
| Multi-centre collaboration | 1 / 3 | OpenAlex lists 2 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 42308323) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Total | 34 / 100 | — |
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