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Individual goal-oriented cognitive rehabilitation to improve everyday functioning for people with early-stage dementia: A multicentre randomised controlled trial (the GREAT trial)
Clare L, Kudlicka A, Oyebode JR, Jones RW, Bayer A, Leroi I, Kopelman M, James IA et al.. International journal of geriatric psychiatry, 2019-03-01
Topic: Risk, prevention and care in population studies
Objectives To determine whether individual goal-oriented cognitive rehabilitation (CR) improves everyday functioning for people with mild-to-moderate dementia. Design and methods Parallel group multicentre single-blind randomised controlled trial (RCT) comparing CR added to usual treatment (CR) with usual treatment alone (TAU) for people with an ICD-10 diagnosis of Alzheimer, vascular or mixed dementia, and mild-to-moderate cognitive impairment (Mini-Mental State Examination [MMSE] score ≥ 18), and with a family member willing to contribute. Participants allocated to CR received 10 weekly sessions over 3 months and four maintenance sessions over 6 months.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Clare, L., Kudlicka, A., Oyebode, JR., Jones, R. W., Bayer, A., Leroi, I., et al. (2019). Individual goal-oriented cognitive rehabilitation to improve everyday functioning for people with early-stage dementia: A multicentre randomised controlled trial (the GREAT trial). International journal of geriatric psychiatry. https://doi.org/10.1002/gps.5076
Vancouver
Clare L, Kudlicka A, Oyebode JR, Jones RW, Bayer A, Leroi I, et al. Individual goal-oriented cognitive rehabilitation to improve everyday functioning for people with early-stage dementia: A multicentre randomised controlled trial (the GREAT trial). International journal of geriatric psychiatry. 2019. doi:10.1002/gps.5076. PMID: 30724405.
BibTeX
@article{clare2019-30724405,
author = {Clare, L. and Kudlicka, A. and Oyebode, JR. and Jones, R. W. and Bayer, A. and Leroi, I. and Kopelman, M. and James, I. A. and others},
title = {{Individual goal-oriented cognitive rehabilitation to improve everyday functioning for people with early-stage dementia: A multicentre randomised controlled trial (the GREAT trial)}},
journal = {International journal of geriatric psychiatry},
year = {2019},
doi = {10.1002/gps.5076},
pmid = {30724405},
url = {https://doi.org/10.1002/gps.5076}
}
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record's author list ends in “et al.”, so not every author is named. Check the citation against the original before you use it.
Key findings
- Design and methods Parallel group multicentre single-blind randomised controlled trial (RCT) comparing CR added to usual treatment (CR) with usual treatment alone (TAU) for people with an ICD-10 diagnosis of Alzheimer, vascular or mixed dementia, and mild-to-moderate cognitive impairment (Mini-Mental State Examination [MMSE] score ≥ 18), and with a family member willing to contribute.
- Participants allocated to CR received 10 weekly sessions over 3 months and four maintenance sessions over 6 months.
- Participants were followed up 3 and 9 months post randomisation by blinded researchers.
- The primary outcome was self-reported goal attainment at 3 months.
Why it matters
This randomised controlled trial tested individual goal-oriented cognitive rehabilitation added to usual treatment for people with mild-to-moderate dementia. It is a trial of a support programme for everyday functioning, not a treatment that cures or prevents Alzheimer's disease.
Study details
- Study designrandomized controlled trial
- Participants475
- Evidence strengthHigh
How this study scored 72/100
Published in a peer-reviewed journal, and it is a randomised controlled trial. Scored zero for effect reported because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (International journal of geriatric psychiatry) |
| Journal's citation record | 2 / 4 | International Journal of Geriatric Psychiatry: journal h-index 190 (OpenAlex, 2026-10-29) |
| Study design | 11 / 12 | A randomised controlled trial |
| Strength of evidence | 5 / 5 | Rated “high” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 2 / 5 | 2019 — within 10 year(s) of the newest study here |
| Sample size | 2 / 4 | 475 participants |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 2 / 2 | Randomised and blinded or placebo-controlled (as stated in the record) |
| Times cited | 5 / 7 | Cited 155 times (OpenAlex, 2026-10-10) |
| Citations per year | 3 / 5 | 17.2 citations a year over 9 year(s) since 2019 |
| Impact for its field and year | 4 / 6 | Cited 13.0× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 2 / 6 | Cited by 5 other studies in this library |
| Still being cited | 3 / 4 | Cited 60 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 3 / 4 | Last-listed author Bob T. Woods: h-index 85 (OpenAlex, whole career) |
| Institution's track record | 1 / 3 | King's College London: institution h-index 1,348 (OpenAlex) |
| Multi-centre collaboration | 3 / 3 | OpenAlex lists 13 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 30724405) |
| Free to read | 2 / 2 | Free to read |
| Total | 72 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
- DOI: 10.1002/gps.5076
- PubMed: 30724405
- Original source →
- Free full text: International Journal of Geriatric Psychiatry →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
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