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A village doctor-led mobile health intervention for cardiovascular risk reduction in rural China: cluster randomised controlled trial
Xingyi Zhang, Siming Wang, Xingyu Zhou, Ya‐Jie Tang, Liying Xing, Shaoning Ma, Xu Yan, Chaoqun Wu et al.. BMJ, 2025-05-27
Topic: Risk, prevention and care in population studies
Plain-language summary
Results Enrolment took place between March 2023 and May 2023. Compared with the control group, the intervention group showed larger reductions in lifetime ASCVD risk (−15.9% v −11.0%; difference −4.59%; Plt;0.001), systolic blood pressure (−23.2 mm Hg v −15.2 mm Hg; difference −7.64 mm Hg; Plt;0.001), diastolic blood pressure (−10.9 mm Hg v −6.9 mm Hg; difference: −3.59 mm Hg; Plt;0.001), fasting blood glucose (−0.9 mmol/L v −0.5 mmol/L; difference −0.30 mmol/L; P=0.008), proportion of daily smokers (−3.1% v −0.6%; odds ratio 0.60, 95% CI 0.43 to 0.84; P=0.003), and insufficient physical activity (−3.0% v 1.3%; odds ratio 0.63, 0.42 to 0.95; P=0.03). No significant differences were observed for change in non-high density lipoprotein cholesterol or proportion of participants with obesity.
What this study adds
Evidence grade: High
This is a trial of 4,533 participants. This trial tested a village doctor-led mobile health intervention in rural China and found improvements in cardiovascular risk factors such as blood pressure, blood glucose and smoking, with no significant change in cholesterol or obesity. Reported effect size: 99.4%; 18.0% to 11.7%; 17.8% to 13.6%.
Taken from this record’s own fields, not from reading the paper. The grade is assigned from the abstract’s wording; what that means.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Zhang, X., Wang, S., Zhou, X., Tang, Y., Xing, L., Ma, S., et al. (2025). A village doctor-led mobile health intervention for cardiovascular risk reduction in rural China: cluster randomised controlled trial. BMJ. https://doi.org/10.1136/bmj-2024-082765
Vancouver
Zhang X, Wang S, Zhou X, Tang Y, Xing L, Ma S, et al. A village doctor-led mobile health intervention for cardiovascular risk reduction in rural China: cluster randomised controlled trial. BMJ. 2025. doi:10.1136/bmj-2024-082765. PMID: 40425261.
BibTeX
@article{zhang2025-40425261,
author = {Zhang, Xingyi and Wang, Siming and Zhou, Xingyu and Tang, Ya‐Jie and Xing, Liying and Ma, Shaoning and Yan, Xu and Wu, Chaoqun and others},
title = {{A village doctor-led mobile health intervention for cardiovascular risk reduction in rural China: cluster randomised controlled trial}},
journal = {BMJ},
year = {2025},
doi = {10.1136/bmj-2024-082765},
pmid = {40425261},
url = {https://doi.org/10.1136/bmj-2024-082765}
}
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record's author list ends in “et al.”, so not every author is named. Check the citation against the original before you use it.
Key findings
- Results Enrolment took place between March 2023 and May 2023.
- Compared with the control group, the intervention group showed larger reductions in lifetime ASCVD risk (−15.9% v −11.0%; difference −4.59%; Plt;0.001), systolic blood pressure (−23.2 mm Hg v −15.2 mm Hg; difference −7.64 mm Hg; Plt;0.001), diastolic blood pressure (−10.9 mm Hg v −6.9 mm Hg; difference: −3.59 mm Hg; Plt;0.001), fasting blood glucose (−0.9 mmol/L v −0.5 mmol/L; difference −0.30 mmol/L; P=0.008), proportion of daily smokers (−3.1% v −0.6%; odds ratio 0.60, 95% CI 0.43 to 0.84; P=0.003), and insufficient physical activity (−3.0% v 1.3%; odds ratio 0.63, 0.42 to 0.95; P=0.03).
- No significant differences were observed for change in non-high density lipoprotein cholesterol or proportion of participants with obesity.
Why it matters
This trial tested a village doctor-led mobile health intervention in rural China and found improvements in cardiovascular risk factors such as blood pressure, blood glucose and smoking, with no significant change in cholesterol or obesity. It did not measure any effect on Alzheimer's disease, dementia or cognition.
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Study details
- Study designrandomized controlled trial
- Participants4,533
- Effect size99.4%; 18.0% to 11.7%; 17.8% to 13.6%
- Evidence strengthHigh
How this study scored 70/100
Published in a leading specialty journal, and it is a randomized controlled trial.
| Component | Points | Why |
|---|---|---|
| Journal tier | 9 / 10 | Tier 2 — leading specialty journal (BMJ) |
| Journal's citation record | 3 / 4 | BMJ: journal h-index 413 (OpenAlex, 2026-10-29) |
| Study design | 11 / 12 | A randomized controlled trial |
| Strength of evidence | 5 / 5 | Rated “high” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 4 / 5 | 2025 — within 3 year(s) of the newest study here |
| Sample size | 3 / 4 | 4,533 participants |
| Effect reported | 2 / 3 | Effect reported as a number, without an interval or test |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomized / blinded | 1 / 2 | Randomized (as stated in the record) |
| Times cited | 2 / 7 | Cited 13 times (OpenAlex, 2026-10-10) |
| Citations per year | 2 / 5 | 4.3 citations a year over 3 year(s) since 2025 |
| Impact for its field and year | 4 / 6 | Cited 11.0× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 1 / 4 | Cited 13 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 3 / 4 | Last-listed author Xi Li: h-index 50 (OpenAlex, whole career) |
| Institution's track record | 1 / 3 | Chinese Academy of Medical Sciences & Peking Union Medical College: institution h-index 950 (OpenAlex) |
| Multicenter collaboration | 2 / 3 | OpenAlex lists 6 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 40425261) |
| Free to read | 2 / 2 | Free to read |
| Total | 70 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
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