Future educational supports for GPs need to be developed which concentrate on these areas. 1 key finding →
Participants: 300 Evidence: low
Full summary, score breakdown and related studies → Original source Full text may need a subscription
28,180 Alzheimer's and dementia studies in plain English, each scored out of 100.
Future educational supports for GPs need to be developed which concentrate on these areas. 1 key finding →
Participants: 300 Evidence: low
Full summary, score breakdown and related studies → Original source Full text may need a subscription
Dementia is an important cause of morbidity in the geriatric population in this community, where families take responsibility for the care of relatives with dementia. 3 key findings →
Participants: 2,067 Evidence: low
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Dementia is under-diagnosed to a greater extent among ethnic minorities in the age group 60 years and older but is over-diagnosed in the age group younger than 60 years. 3 key findings →
Participants: 219 Evidence: low
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Since the original description of amyloid-β plaques and tau tangles more than 100 years ago, these lesions have been considered the neuropathological hallmarks of Alzheimer disease (AD). 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Nonresponders in community surveys of the elderly appear to be disproportionately cognitively impaired. 3 key findings →
Design: cross-sectional Evidence: low
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Cognitive assessment is a basic element for dementia diagnosis. 2 key findings →
Design: cross-sectional Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
These results suggest that mechanisms leading to atherosclerosis might also lead to an increased number of perivascular spaces. 5 key findings →
Participants: 706 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Little information exists on the performance of black versus white patients with Alzheimer's disease on neuropsychological tests for dementia. 2 key findings →
Participants: 830 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
NLR may be useful to identify and stratify patients who could benefit from adjunctive anti-inflammatory treatment. 1 key finding →
Design: cross-sectional Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Improving transportation access and diabetes care may be important targets for enhancing mobility and reducing racial disparities in mobility. 1 key finding →
Design: cohort study Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
SMC was associated with poorer objective memory performance even after controlling the effect of depression and demographic data, but SMC did not predict faster cognitive decline or dementia over 3 years. 5 key findings →
Participants: 543 Evidence: low
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Previous studies have suggested that 4 latent constructs (depressed affect, well-being, interpersonal problems, somatic symptoms) underlie the item responses on the Center for Epidemiological Studies Depression (CES-D) Scale. 3 key findings →
Participants: 1,183 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Over the next 25 years, the prevalence of dementia in people older than 65 years is projected to exceed 25% nationwide, including metropolitan areas. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
As individuals age, the quality of cognitive function becomes an increasingly important topic. 5 key findings →
Evidence: high
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The prevalence of dementia is increasing in our aging population at an alarming rate. 5 key findings →
Evidence: low
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In contrast to newborns, who spend 16-20 h in sleep each day, adults need only about sleep daily. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Maintenance of brain function depends on a constant blood supply. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
While sarcasm can be conveyed solely through contextual cues such as counterfactual or echoic statements, face-to-face sarcastic speech may be characterized by specific paralinguistic features that alert the listener to interpret the utterance as ironic or critical, even in the absence of contextual information. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Primary progressive aphasia (PPA) is a clinical dementia syndrome with early symptoms of language dysfunction. 1 key finding →
Participants: 16 Evidence: low
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The human anterior insula is anatomically and functionally heterogeneous, containing key nodes within distributed speech-language and viscero-autonomic/social-emotional networks. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Recent findings Corticobasal degeneration and PSP are neurodegenerative diseases characterized by neuronal loss and gliosis in cardinal brain regions, as well as the abnormal deposition of the microtubule associated protein tau in cell bodies and cell processes. 2 key findings →
Evidence: low
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10 years into PD, a significant proportion of patients developed dopa resistant motor and non-motor features. 3 key findings →
Evidence: moderate
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Hereditary frontotemporal dementia (HFTD) is a rare autosomal dominant form of presenile dementia characterized by behavioral changes and reduced speech. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Twenty-one patients showed FDG hypometabolism; the remaining 3 did not. 1 key finding →
Participants: 24 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Language impairment is an important biomarker of neurodegenerative disorders such as Alzheimer's disease (AD). 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 28,180 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 28,180 records, built mostly from automated pulls of Europe PMC (61.7% of the library) and OpenAlex (18.1%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,034 records (3.7% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →