27,380 Alzheimer's and dementia studies in plain English, each scored out of 100.
Among 2144 participants (540 deaths over a median 4.4 years of survivor follow-up; 25% mortality), the seven-marker score plus age and sex achieved an apparent C of 0.74 (optimism-corrected 0.74), versus 0.68 for age and sex alone (Δ ≈ 0.06); the blood panel alone reached C 0.72. 2 key findings →
Design: longitudinal study Participants: 2,144 Evidence: moderate
Full summary, score breakdown and related studies → Original source
The SPICT-TR is a culturally adapted, valid, and reliable assessment tool for identifying patients with palliative care needs within the Turkish healthcare system. 4 key findings →
Participants: 356 Evidence: low
Full summary, score breakdown and related studies → Original source
We examined how often each diagnosed disease appeared on the certificate, its location and selection as the UCD, factors associated with its appearance (logistic regression), disease-specific mortality (multiple decrement life tables), and disease associations (Cause of Death Association Indicator, CDAI). 3 key findings →
Evidence: moderate
Full summary, score breakdown and related studies → Original source
Data collection started on June 3, 2026, and is planned to close on June 30, 2026. 2 key findings →
Design: cross-sectional Evidence: low
Full summary, score breakdown and related studies → Original source
We included 23 studies with qualitative (73.9%) or quantitative/mixed-methods (26.1%) designs. 5 key findings →
Design: longitudinal study Participants: 23 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Persons with dementia (PWD) and their care partners experience multidimensional care transitions across the illness trajectory. 1 key finding →
Participants: 20 Evidence: low
Full summary, score breakdown and related studies → Original source
Forty‑two studies published between 1997 and 2025 were included. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Polypharmacy and PIMs are highly prevalent in end-of-life elderly cancer patients. 3 key findings →
Design: cross-sectional Participants: 183 Evidence: low
Full summary, score breakdown and related studies → Original source
Recorded PD-related mortality was lower among Black than White adults, whereas AD-related mortality showed no statistically significant racial difference. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
This nationwide study provides epidemiological data on dementia and MCI among adults aged ≥ 60 years across all 12 administrative regions of Morocco. 1 key finding →
Design: cross-sectional Participants: 1,662 Evidence: low
Full summary, score breakdown and related studies → Original source
Memory IIV may be more closely linked to hippocampal white matter, while mean memory performance may better reflect hippocampal volume. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
This study reports the prevalence of CF among elderly hypertensive residents of a community in Inner Mongolia. 5 key findings →
Design: cross-sectional Evidence: low
Full summary, score breakdown and related studies → Original source
Drama therapy is in an accelerated growth phase, with substantial scholarly expansion expected over the next two decades. 4 key findings →
Participants: 785 Evidence: high
Full summary, score breakdown and related studies → Original source
In a contemporary, diverse cohort, most established dementia risk algorithms had limited power in discriminating amyloid positivity, pTau-217 positivity, and current cognitive status despite acceptable calibration. 3 key findings →
Participants: 603 Evidence: moderate
Full summary, score breakdown and related studies → Original source
This study demonstrated MMSE scores can be systematically extracted and curated from the VA EHR. 3 key findings →
Design: cross-sectional Participants: 49,555 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Changes in four outcome measures from initiation of treatment to discharge were evaluated for statistical significance: quality of life and three therapist-rated Functional Communication Measures (FCMs) of overall cognition, language expression, and language comprehension. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
We validated results in CSF from 397 participants in the Accelerated Medicine Partnership-Alzheimer’s Disease cohort. 5 key findings →
Participants: 500 Evidence: moderate
Full summary, score breakdown and related studies → Original source
We found opposite effects of age on FMAR at both short and long time scales, respectively (ßAge=0.014, 95% C.I. [0.009,0.019] and ßAge=-0.015, 95% C.I. [-0.026,-0.005]), as well as differences between women and men at long time scales (ßSexMen=+0.028, 95% C.I. [0.012,0.044]). 5 key findings →
Design: cross-sectional Evidence: moderate
Full summary, score breakdown and related studies → Original source
Neurodegenerative conditions increasingly adopt digital and assistive technologies in community and home-based settings to support independence, symptom management and quality of life. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
In SPRINT, intensive vs standard SBP control yielded a significantly larger 4-year absolute risk reduction in dementia among APOE ε4 carriers (−1.7%) than non-carriers (0.2%; P-interaction = .045); the relative-scale interactions were directionally consistent but not significant. 3 key findings →
Design: randomized controlled trial Evidence: high
Full summary, score breakdown and related studies → Original source
Lifetime TBI exposure is associated with increased likelihood and long-term risk of psychiatric disorders in individuals with dementia, stroke, and Parkinson’s disease, with mood disorders being the most consistent outcome across conditions. 4 key findings →
Participants: 502,154 Evidence: moderate
Full summary, score breakdown and related studies → Original source
In this setting, selective participation had only a limited effect on prevalence estimates after weighting. 2 key findings →
Participants: 25,977 Evidence: low
Full summary, score breakdown and related studies → Original source
People with Down syndrome have higher age-specific mortality rates compared to the general population as well as peers with other intellectual and developmental disabilities. 2 key findings →
Design: case-control study Participants: 137,293 Evidence: moderate
Full summary, score breakdown and related studies → Original source
We recommend using a broad (ADRD) algorithm without CMS or medication data, particularly for epidemiological studies or a strict AD algorithm including CMS and medication cases for genetic discovery of late-onset AD associations in VA EMR, and a strict AD algorithm without CMS data for applications focused solely on AD and sensitive to misspecification. 3 key findings →
Evidence: moderate
Full summary, score breakdown and related studies → Original source
Earlier diagnosis increases total expenditures but improves care and cost allocation. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 27,380 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,380 records, built mostly from automated pulls of Europe PMC (60.6% of the library) and OpenAlex (18.6%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,032 records (3.8% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →