27,380 Alzheimer's and dementia studies in plain English, each scored out of 100.
We found declining dementia incidence but increasing dementia prevalence in a sample that includes the vast majority of older adults in the United States. 3 key findings →
Participants: 1,000 Evidence: moderate
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Overall, these findings highlight the generally robust, protective effect of social support on cognitive abilities in this large, diverse cohort of older adults. 5 key findings →
Participants: 2,811 Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
= 0.14. The effect of ADI score was also significant, β = -0.36, t = -2.30, p < .05; while the effect of RUCC, β = 0.06, t = 0.34, p = .73, and the interaction between ADI and RUCC, β = -0.001, t = 0.27, p = .99, were nonsignificant. 3 key findings →
Design: cross-sectional Participants: 114 Evidence: low
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Among 5757 participants (21.7% Black, 20.3% Latinx, 58.1% AORE), we found lower odds of amyloid positivity in Black (odds ratio [OR]: 0.72, 95% confidence interval [CI]: 0.62-0.83) and Latinx (OR: 0.78, 95% CI: 0.67-0.91) compared to AORE. 4 key findings →
Participants: 5,757 Evidence: moderate
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Lower objective SES was associated with poorer performance on all cognitive domains: episodic memory (β = 0.115, p = 0.003), executive function (β = 0.210, p 0.05). 5 key findings →
Design: cross-sectional Evidence: high
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Higher ADI was significantly associated with increased CRP (r=0.469, p = 0.002) and TREM-1 (r=0.316, p = 0.047). 5 key findings →
Design: cross-sectional Participants: 40 Evidence: moderate
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We found 5 distinct clusters of subjects (N=38, N=16, N=24, N=14, N=21) with a composition statistically independent from that obtained using available clinical diagnostic criteria (each cluster included all phenotypical groups). 3 key findings →
Participants: 20 Evidence: moderate
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Loneliness moderated the relationship between national ADI scores and short-term visuospatial memory. 5 key findings →
Design: cross-sectional Participants: 136 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Dementia is a growing problem of global relevance, currently affecting over 55 million people worldwide. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Many medical and epidemiological studies use multivariable regression to test whether several independent variables (exposures) are causal determinants of a health outcome. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Delirium, a severe neuropsychiatric syndrome characterised by acute deficits in attention and self-awareness, is common among elderly inpatients, with incidence increasing with age and prolonged hospitalisation. 2 key findings →
Participants: 89 Evidence: low
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Metabolomics provide a promising tool for understanding dementia pathogenesis and identifying novel biomarkers. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Evidence is accumulating which suggests that, in addition to leading to unprecedented rates of obesity, the current food environment is contributing to the development of cognitive impairment and dementia. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Older adults with Alzheimer's disease (AD) frequently present to emergency departments (EDs) with multiple coexisting conditions. 5 key findings →
Design: cross-sectional Participants: 125,461 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Socioeconomic disadvantage is recognized as a risk factor for cognitive decline, yet its associated neural pathways remain unclear. 5 key findings →
Participants: 822 Evidence: low
Full summary, score breakdown and related studies → Original source
Bivariate analyses showed that chain grocery store shoppers reported significantly greater fruit and vegetable intake (2.42 vs. 2.14 times/day for independent grocery store shoppers, p < 0.001) and lower rates of food insecurity compared to independent store shoppers (45.9% vs. 65.3% for independent grocery store shoppers, p < 0.001). 5 key findings →
Design: cross-sectional Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Due to rapidly aging populations, the number of people worldwide experiencing dementia is increasing, and the projections are grim. 1 key finding →
Evidence: low
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Hypertension is a global health problem, with >1.3 billion individuals with high blood pressure worldwide. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Several plant bioactive compounds have exhibited functional activities that suggest they could play a remarkable role in preventing a wide range of chronic diseases. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Disruptions of normal circadian rhythms and sleep cycles are consequences of aging and can profoundly affect health. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Astrocytes serve important roles that affect recruitment and function of neurons at the local and network levels. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Sleep disturbances are associated with future risk of Alzheimer disease. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
We examined five patients with Alzheimer's disease who complained of poor vision. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Age-related hearing loss (ARHL), presbycusis, is a chronic health condition that affects approximately one-third of the world's population. 1 key finding →
Design: narrative review Evidence: low
Full summary, score breakdown and related studies → Original source
VR immersion training is an effective teaching method to help medical and health professions students develop empathy and is a budding area for library partnerships. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 27,380 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,380 records, built mostly from automated pulls of Europe PMC (60.6% of the library) and OpenAlex (18.6%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,032 records (3.8% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →