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Research

27,380 Alzheimer's and dementia studies in plain English, each scored out of 100.

Find studies

Showing 1–25 of 28 studies in Cognitive tests and assessment published 2012 (page 1 of 2) · 27,380 in the whole library · How the 0–100 score works

Browse by subject, author or institution

Each number is how many studies that link shows, with your other filters kept.

Other subjects

Authors

Names as each record prints them; the same person can appear under two spellings.

Institutions

From OpenAlex; 12,859 studies have no institution on record and are not counted here.

What “Cognitive tests and assessment” covers

Cognitive tests and assessment — Memory and thinking tests, screening tools and rating scales: how well they measure what they claim to.

A note on reading research. One study is rarely the final word.

We try to note the size of a study, whether it was in humans or animals, and how early-stage the finding is. If a summary here doesn't make that clear, treat it with extra caution and check the original source.

Excessive sleepiness is predictive of cognitive decline in the elderly

✓ Peer-reviewed alzhub usefulness score 68 out of 100. Sleep 2012-09-01

Study objectives To examine the association of sleep complaints reported at baseline (insomnia complaints and excessive daytime sleepiness (EDS)) and medication, with cognitive decline in community-dwelling elderly. 4 key findings →

Design: longitudinal study Participants: 4,894 Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

Effects of ω-3 fatty acids on cognitive performance: a meta-analysis

✓ Peer-reviewed alzhub usefulness score 65 out of 100. Neurobiology of aging 2012-02-03

Higher intake of omega-3 fatty acids (n-3 FAs) is associated with a reduced risk of Alzheimer's disease (AD) and milder forms of cognitive impairment (e.g. cognitive impairment no dementia [CIND]); however, findings from interventional trials are inconsistent. 4 key findings →

Design: meta-analysis Participants: 934 Evidence: high

Full summary, score breakdown and related studies → Original source Full text may need a subscription

Progression of Alzheimer's disease as measured by Clinical Dementia Rating Sum of Boxes scores

✓ Peer-reviewed alzhub usefulness score 62 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2012-08-01

This study examined rates of dementia progression as ascertained by the Clinical Dementia Rating Sum of Boxes (CDR-SB) for symptomatic Alzheimer's disease (sAD), and assessed participant characteristics as predictors of CDR-SB progression. 3 key findings →

Design: longitudinal study Participants: 792 Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

Development and assessment of a composite score for memory in the Alzheimer's Disease Neuroimaging Initiative (ADNI)

✓ Peer-reviewed alzhub usefulness score 60 out of 100. Brain imaging and behavior 2012-12-01

We sought to develop and evaluate a composite memory score from the neuropsychological battery used in the Alzheimer's Disease (AD) Neuroimaging Initiative (ADNI). 4 key findings →

Design: longitudinal study Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

Increased risk of cognitive and functional decline in patients with atrial fibrillation: results of the ONTARGET and TRANSCEND studies

✓ Peer-reviewed alzhub usefulness score 59 out of 100. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 2012-02-27

The role of atrial fibrillation in cognitive impairment and dementia, independent of stroke, is uncertain. 4 key findings →

Design: post-hoc analysis Participants: 31,506 Evidence: high

Full summary, score breakdown and related studies → Original source Free full text

Cerebral microbleeds are associated with worse cognitive function: the Rotterdam Scan Study

✓ Peer-reviewed alzhub usefulness score 58 out of 100. Neurology 2012-01-18

Cerebral microbleeds are frequently found in the general elderly population and may reflect underlying vascular disease, but their role in cognitive function is unknown. 4 key findings →

Participants: 3,979 Evidence: low

Full summary, score breakdown and related studies → Original source Full text may need a subscription

Symptoms of rapid eye movement sleep behavior disorder are associated with cholinergic denervation in Parkinson disease

✓ Peer-reviewed alzhub usefulness score 54 out of 100. Annals of neurology 2012-04-01

Rapid eye movement sleep behavior disorder (RBD) is common in Parkinson disease (PD), but its relationship to the varied neurotransmitter deficits of PD and prognostic significance remain incompletely understood. 4 key findings →

Participants: 35 Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Reliability of six physical performance tests in older people with dementia

✓ Peer-reviewed alzhub usefulness score 53 out of 100. Physical therapy 2012-09-13

Physical performance tests are important for assessing the effect of physical activity interventions in older people with dementia, but their psychometric properties have not been systematically established within this specific population. 4 key findings →

Design: cross-sectional Participants: 58 Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Rationale for use of the Clinical Dementia Rating Sum of Boxes as a primary outcome measure for Alzheimer's disease clinical trials

✓ Peer-reviewed alzhub usefulness score 52 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2012-06-01

The CDR-SB assesses both cognitive and functional domains of AD disability. 4 key findings →

Participants: 382 Evidence: low

Full summary, score breakdown and related studies → Original source Full text may need a subscription

The Alzheimer's Disease Assessment Scale-Cognitive-Plus (ADAS-Cog-Plus): an expansion of the ADAS-Cog to improve responsiveness in MCI

✓ Peer-reviewed alzhub usefulness score 51 out of 100. Brain imaging and behavior 2012-12-01

The Alzheimer's Disease Assessment Scale cognitive subscale (ADAS-Cog) is widely used in AD, but may be less responsive to change when used in people with mild cognitive impairment (MCI). 4 key findings →

Participants: 811 Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

The disappearing subject: exclusion of people with cognitive impairment and dementia from geriatrics research

✓ Peer-reviewed alzhub usefulness score 50 out of 100. Journal of the American Geriatrics Society 2012-01-30

All original research articles published in 2008 and 2009 in the Journal of the American Geriatrics Society (n = 434) were reviewed using a structured data collection tool. 4 key findings →

Participants: 434 Evidence: low

Full summary, score breakdown and related studies → Original source Full text may need a subscription

The Montreal Cognitive Assessment is superior to the Mini-Mental State Examination in detecting patients at higher risk of dementia

✓ Peer-reviewed alzhub usefulness score 49 out of 100. International psychogeriatrics 2012-06-12

Memory clinic patients were administered the MoCA, MMSE, and a comprehensive formal neuropsychological battery. 4 key findings →

Participants: 36 Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Comparison of the quick mild cognitive impairment (Qmci) screen and the SMMSE in screening for mild cognitive impairment

✓ Peer-reviewed alzhub usefulness score 49 out of 100. Age and ageing 2012-05-18

The AB Cognitive Screen (ABCS) 135, sensitive in differentiating MCI from dementia, was modified to improve sensitivity and specificity, producing the quick mild cognitive impairment (Qmci) screen. 4 key findings →

Participants: 630 Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Microglial activation and TDP-43 pathology correlate with executive dysfunction in amyotrophic lateral sclerosis

✓ Peer-reviewed alzhub usefulness score 48 out of 100. Acta neuropathologica 2012-01-01

While cognitive deficits are increasingly recognized as common symptoms in amyotrophic lateral sclerosis (ALS), the underlying histopathologic basis for this is not known, nor has the relevance of neuroinflammatory mechanisms and microglial activation to cognitive impairment (CI) in ALS been systematically analyzed. 4 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Weight loss and rapid cognitive decline in community-dwelling patients with Alzheimer's disease

✓ Peer-reviewed alzhub usefulness score 48 out of 100. Journal of Alzheimer's disease : JAD 2012-01-01

Weight loss is a frequent complication of Alzheimer's disease (AD) and a strong predictor of adverse outcomes in patients suffering from this disease. 4 key findings →

Evidence: moderate

Full summary, score breakdown and related studies → Original source Full text may need a subscription

Microglia, amyloid, and glucose metabolism in Parkinson's disease with and without dementia

✓ Peer-reviewed alzhub usefulness score 47 out of 100. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2012-12-06

[(11)C](R)PK11195-PET measures upregulation of translocator protein, which is associated with microglial activation, [(11)C]PIB-PET is a marker of amyloid, while [(18)F]FDG-PET measures cerebral glucose metabolism (rCMRGlc). 4 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

The Modified Mini-Mental State Examination test: normative data for Singapore Chinese older adults and its performance in detecting early cognitive impairment

✓ Peer-reviewed alzhub usefulness score 46 out of 100. Singapore medical journal 2012-07-01

This study aimed to determine the stratified normative data by age and education for a modified version of the Mini-Mental State Examination (MMSE) test from a large sample of community-dwelling Chinese older adults in Singapore, and to examine the MMSE's value in detecting early cognitive impairment. 4 key findings →

Participants: 1,763 Evidence: low

Full summary, score breakdown and related studies → Original source Full text may need a subscription

Validity of a brief computerized cognitive screening test in dementia

✓ Peer-reviewed alzhub usefulness score 43 out of 100. Journal of geriatric psychiatry and neurology 2012-06-01

CogState and standard neuropsychological task scores were significantly lower for dementia participants than that of the nondementia groups (P < .05), with a single CogState test distinguishing control from MCI participants, but minimal differentiation existing between dementias using the CogState. 2 key findings →

Participants: 37 Evidence: low

Full summary, score breakdown and related studies → Original source

Evaluation of chewing ability and its relationship with activities of daily living, depression, cognitive status and food intake in the community-dwelling elderly

✓ Peer-reviewed alzhub usefulness score 42 out of 100. Geriatrics & gerontology international 2012-12-21

The aim of this study was to assess chewing ability using color-changeable chewing gum and to show the association between chewing ability and geriatric functions, as well as dietary status in the community-dwelling elderly. 4 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source Full text may need a subscription

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Where “Free full text” comes from

Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read

How the 0–100 score works — and why some entries are capped

This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.

  • Journal tier up to 10 pts
  • Journal's citation record up to 4 pts
  • Study design up to 12 pts
  • Strength of evidence up to 5 pts
  • Peer-review validation up to 10 pts
  • How recent up to 5 pts
  • Sample size up to 4 pts
  • Effect reported up to 3 pts
  • Studied in people up to 3 pts
  • Randomised / blinded up to 2 pts
  • Times cited up to 7 pts
  • Citations per year up to 5 pts
  • Impact for its field and year up to 6 pts
  • Cited by studies here up to 6 pts
  • Still being cited up to 4 pts
  • Senior author's track record up to 4 pts
  • Institution's track record up to 3 pts
  • Multi-centre collaboration up to 3 pts
  • Indexed in PubMed up to 2 pts
  • Free to read up to 2 pts

Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.

Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.

We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.

The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.

See the whole rubric drawn out → — four charts covering all 27,380 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.

What this library is — and isn't

This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,380 records, built mostly from automated pulls of Europe PMC (60.6% of the library) and OpenAlex (18.6%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.

1,032 records (3.8% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.

See the full, machine-readable breakdown of this library's coverage →

Newest studies, as a dated timeline →    Atom feed