62/100
✓ Peer-reviewed
alzhub usefulness score 62 out of 100.
·
EP Europace
·
2022-08-24
Atrial fibrillation (AF) is the most common clinical arrhythmia with substantial health and socioeconomic impact on healthcare.1 The number of people affected by this condition was estimated to be 33.5 million in 2010, with an increasing prevalence and incidence over the coming years.2 In 2017, there were 37.6 million [95% confidence interval (CI): 32.5–42.6 million] individuals with AF/atrial flutter globally.3 The estimated number of subjects with AF in 2030 in Europe will be 14–17 million, and the number of new cases of AF per year at 120 000–215 000.4 Atrial fibrillation is independently associated with increased mortality and morbidity from complications such as ischaemic stroke, dementia, and cognitive dysfunction.5 Oral anticoagulation can significantly reduce the risk of stroke, dementia, and death.6 As a part of a holistic or integrated approach to AF care, it is associated with improved outcomes7–9 and is advocated in guidelines.10,11 In many patients, AF can be asymptomatic, and the diagnosis is established after the appearance of a complication typically associated with AF, such as ischaemic stroke/systemic embolic or heart failure. 5 key findings →
Participants: 280
Evidence: high
Full summary, score breakdown and related studies →
Original source
Therefore, respective software was developed in-house.8,9 Segmentation results are then analysed for potential associations with disease risks and to establish reference intervals of organ size and function.10 SHIP is also used as a basis for meta-research with a particular focus on incidental MRI findings and their effects on study participants.11,12 With its large amount of standardized data and the option to internally replicate findings from SHIP-START using data of the independent SHIP-TREND, the project offers good opportunities to apply new bioinformatical tools to mine the data and gain new insights into risk factors and pathomechanisms. 4 key findings →
Design: longitudinal study
Evidence: moderate
Full summary, score breakdown and related studies →
Original source
The study has been harmonized with leading international research so as to ensure adoption of best practice and comparability of results. 3 key findings →
Design: cohort study
Participants: 25
Evidence: moderate
Full summary, score breakdown and related studies →
Original source
n d e n c e Changes in the Place of Death in the United States To the Editor: Where people die is an impor tant determinant of patient and caregiver expe rience.
Participants: 905,874
Evidence: low
Full summary, score breakdown and related studies →
Original source
We sought to assess risk of COVID-19 among front-line health-care workers compared with the general community and the effect of personal protective equipment (PPE) on risk. 2 key findings →
Design: cohort study
Evidence: moderate
Full summary, score breakdown and related studies →
Original source
Patients with BP are more likely to have various neurological diseases, schizophrenia and psoriasis prior to the diagnosis of BP, supporting associations found in other studies. 3 key findings →
Design: case-control study
Participants: 3,485
Evidence: moderate
Full summary, score breakdown and related studies →
Original source
60/100
✓ Peer-reviewed
alzhub usefulness score 60 out of 100.
·
BMJ open
·
2015-05-14
The impact of comorbidities present at the time of transplantation changes with time after transplantation. 5 key findings →
Design: cohort study
Evidence: moderate
Full summary, score breakdown and related studies →
Original source
Illness duration and symptom prevalence, duration, and burden were analysed for children testing positive for SARS-CoV-2 for whom illness duration could be determined, and were assessed overall and for younger (age 5-11 years) and older (age 12-17 years) groups. 4 key findings →
Design: cohort study
Evidence: moderate
Full summary, score breakdown and related studies →
Original source
59/100
✓ Peer-reviewed
alzhub usefulness score 59 out of 100.
·
Stroke
·
1997-03-01
Risk of VaD was associated with history of arterial hypertension (OR, 2.08; 95% confidence interval, 1.29 to 3.35). 5 key findings →
Design: case-control study
Participants: 129
Evidence: moderate
Full summary, score breakdown and related studies →
Original source
This prospective, community-based, nested, case-control study used self-reported data (eg, on demographics, geographical location, health risk factors, and COVID-19 test results, symptoms, and vaccinations) from UK-based, adult (≥18 years) users of the COVID Symptom Study mobile phone app. 5 key findings →
Design: case-control study
Evidence: moderate
Full summary, score breakdown and related studies →
Original source
57/100
✓ Peer-reviewed
alzhub usefulness score 57 out of 100.
·
Military medicine
·
2017-09-01
Repeat HF hospitalizations remain a strong predictor of mortality for existing patients with HF. 3 key findings →
Participants: 51,286
Evidence: moderate
Full summary, score breakdown and related studies →
Original source
GIM services care for a markedly heterogeneous population but the most common conditions were similar across 7 hospitals. 3 key findings →
Design: cross-sectional
Participants: 223
Evidence: low
Full summary, score breakdown and related studies →
Original source
We found higher risks of COVID-19-related outcomes among Black and Hispanic individuals. 5 key findings →
Participants: 138,533
Evidence: low
Full summary, score breakdown and related studies →
Original source
57/100
✓ Peer-reviewed
alzhub usefulness score 57 out of 100.
·
Circulation
·
1999-05-11
C oronary heart disease (CHD) is the single leading cause of death and a significant cause of morbidity among American women. 1 Risk factors for CHD in women are well documented. 2 Compelling data from epidemiological studies and randomized clinical trials show that CHD is largely preventable.
Participants: 2,763
Evidence: high
Full summary, score breakdown and related studies →
Original source
Older adults with hip fracture are at risk for underassessment of pain, considerable delays in analgesic administration after pain is identified, and treatment with inappropriate analgesics (e.g., meperidine) in the ED. 3 key findings →
Design: cohort study
Evidence: moderate
Full summary, score breakdown and related studies →
Original source
The use of methods that focus on determining a single underlying cause may lead to underestimation of the extent of the contribution of some diseases such as dementia and respiratory disease to death in older adults and overestimation of the contribution of other diseases. 1 key finding →
Design: longitudinal study
Evidence: moderate
Full summary, score breakdown and related studies →
Original source
55/100
✓ Peer-reviewed
alzhub usefulness score 55 out of 100.
·
Medical care
·
2014-03-01
Claims data studies that include indicators of potentially diminished patient functional status better capture heterogeneity of patients with multiple chronic conditions. 1 key finding →
Participants: 72,056
Evidence: moderate
Full summary, score breakdown and related studies →
Original source
The purpose of this study was to identify the specific patient comorbidities that are associated with an increased risk of periprosthetic joint infection and of ninety-day postoperative mortality in U.S. Results Comorbid conditions associated with an increased adjusted risk of periprosthetic joint infection (in decreasing order of significance, p < 0.05 for all comparisons) were rheumatologic disease (hazard ratio [HR] = 1.71), obesity (HR = 1.73), coagulopathy (HR = 1.58), and preoperative anemia (HR = 1.36). 4 key findings →
Participants: 40,919
Evidence: low
Full summary, score breakdown and related studies →
Original source
Men with prostate cancer treated with androgen deprivation therapy had a higher likelihood of developing new comorbidities than men who did not receive androgen deprivation therapy. 3 key findings →
Design: cohort study
Evidence: moderate
Full summary, score breakdown and related studies →
Original source
The factors associated with excess risk that have been identified are: serum cholesterol level, blood pressure, cigarette smoking, vital capacity,...References1. 1 key finding →
Design: cross-sectional
Evidence: high
Full summary, score breakdown and related studies →
Original source
NIH Conferences21 June 2005National Institutes of Health State-of-the-Science Conference Statement: Management of Menopause-Related SymptomsFREENIH State-of-the-Science Panel*NIH State-of-the-Science Panel*Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-142-12_Part_1-200506210-00117 SectionsAboutVisual AbstractPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail National Institutes of Health (NIH) consensus and state-of-the-science statements are prepared by independent panels of health professionals and public representatives on the basis of 1) the results of a systematic literature review prepared under contract with the Agency for Healthcare Research and Quality (AHRQ), 2) presentations by investigators working in areas relevant to the conference questions during a 2-day public session, 3) questions and statements from conference attendees during open discussion periods that are part of the public session, and 4) closed deliberations by the panel during the remainder of the second day and the morning of the third. 5 key findings →
Design: cross-sectional
Evidence: high
Full summary, score breakdown and related studies →
Original source
The mean age was 72 years (49-90 years), and 44 (62%) patients were female. 1 key finding →
Participants: 71
Evidence: low
Full summary, score breakdown and related studies →
Original source
52/100
✓ Peer-reviewed
alzhub usefulness score 52 out of 100.
·
PharmacoEconomics
·
1999-04-01
This study provides health economists, researchers and policy-makers with a reference for health utilities of various chronic conditions, different age groups, gender and comorbidities. 2 key findings →
Participants: 17,626
Evidence: low
Full summary, score breakdown and related studies →
Original source
SSAE-3/5 scores correlated with BGTS scores, with high inter-reader intraclass correlation coefficients across all scales. 3 key findings →
Participants: 75
Evidence: low
Full summary, score breakdown and related studies →
Original source
A rise in the incidence of bullous pemphigoid (BP) was documented recently in Europe, and the main risk factors for BP remain unknown. 2 key findings →
Design: case-control study
Evidence: moderate
Full summary, score breakdown and related studies →
Original source
How the 0–100 score works — and why some entries are capped
This is alzhub's own score. It is not an official metric, not an impact factor,
and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a
scientist can tell a landmark trial from a conference abstract without having to already know the
difference. Every point comes from one of 20 components, all of them printed on the study itself,
so you can disagree with our arithmetic rather than having to trust the total.
- Journal tier up to 10 pts
- Journal's citation record up to 4 pts
- Study design up to 12 pts
- Strength of evidence up to 5 pts
- Peer-review validation up to 10 pts
- How recent up to 5 pts
- Sample size up to 4 pts
- Effect reported up to 3 pts
- Studied in people up to 3 pts
- Randomised / blinded up to 2 pts
- Times cited up to 7 pts
- Citations per year up to 5 pts
- Impact for its field and year up to 6 pts
- Cited by studies here up to 6 pts
- Still being cited up to 4 pts
- Senior author's track record up to 4 pts
- Institution's track record up to 3 pts
- Multi-centre collaboration up to 3 pts
- Indexed in PubMed up to 2 pts
- Free to read up to 2 pts
Journals are placed in ordered tiers, never given a numeric impact factor — we
could not verify current impact factors from a source we control, and an invented one would be
worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science,
Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed
journal. A separate part scores how much the journal's own papers are cited, which tells the
tier-3 journals apart.
Two rules we don't bend. First, we never fill in a
missing value: if a record does not state a sample size or a design, that component scores
zero, and if we simply have no data for a part, such as a citation count, that part is left out and
the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed
article is capped at 16/100 and carries a warning chip — so a conference abstract or
a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not
work — above an early positive finding. Someone deciding whether to buy a supplement is served by
that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is
reproducible: the same file always yields the same numbers.
See the whole rubric drawn out →
— four charts covering all 27,780 studies: how the scores are spread and where the cap
bites, which of the 20 components the library is strong and weak on, which subjects rest on
stronger evidence, and what kinds of study each subject is actually built from.