In adults aged ≥65 years, dementia with CAD was the cause of 1,256,284 deaths between 1999 and 2023. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Research
27,380 Alzheimer's and dementia studies in plain English, each scored out of 100.
A total of eight studies were included from 1,384 search results, reviewing data from 10,449 cognitively unimpaired older adults. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Our studies showed that DC and DRs in VD and AD groups were significantly lower than those in controls, while AC values were significantly higher. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Lithium is a naturally occurring trace element with established neuroprotective and psychotropic properties at pharmacologic doses. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Full text may need a subscription
Previous research has found that living in a disadvantaged neighborhood is associated with poor health outcomes. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
SDOH are potentially modifiable factors, therefore, a deeper understanding of their effects on ADRD can inform future interventions aimed at reducing ADRD prevalence and disparities. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
In highly segregated counties, Black older adults with elevated CVD demonstrated worse memory than those with lower CVD; in less segregated counties, memory levels did not differ by CVD. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
This study aimed to investigate the bidirectional causal relationship between celiac disease (CD) and the risk of Alzheimer disease (AD) or frontotemporal dementia (FTD) using Mendelian randomization (MR), in order to clarify prior inconsistent findings. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Mean activity from actigraphy did not differ within dyad members. 5 key findings →
Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
Keeping current with the burden and risk factors of Alzheimer disease and other dementias (ADOD) from global to national levels is critical for healthcare planning, prevention strategies, and the allocation of resources. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
33/100
Modifiable risk factors associated with dementia were common in AA and NHW participants. 5 key findings →
Participants: 261 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Fifty-four participants (~8% response rate) from the MindCrowd web-based cohort (mean age of 62.39 years; 39 females; and 23 APOE ε4 carriers) completed 75 trials of Super G. Results show that Super G performance was significantly associated with each of the targeted risk factors. 5 key findings →
Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
Our findings reinforce the notion of a bidirectional association between epilepsy and AD, providing proof-of-concept that epilepsy, especially late-onset, may be successfully integrated into AD risk frameworks. 5 key findings →
Evidence: moderate
Full summary, score breakdown and related studies → Original source Full text may need a subscription
This study aimed to investigate the association between delirium and incident dementia in elderly (≥65 years) type 2 diabetes mellitus (T2DM) patients, addressing the heightened dementia risk in this population. newly diagnosed between January 1, 2005, and December 31, 2007. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Full text may need a subscription
This study aimed to determine the effectiveness of regular dental scaling by evaluating the association between the frequency of dental scaling and the risk of dementia in individuals with moderate to severe periodontal disease. 2 key findings →
Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
The model outperformed conventional ones, with an out-of-bag R2 of 74.8%. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Thirty thousand three hundred and ninety-eight deaths attributable to dementia as the underlying or related cause (multiple causes) were reported during 2015-2019. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Understanding and addressing SDOH associated with hospitalizations among AI/AN older adults, with and without dementia, may aid in the development of strategies that reduce preventable hospitalization. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Participants exhibited strong awareness of the risks associated with complications and the severity of chronic diseases. 5 key findings →
Design: cross-sectional Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
The overall NH admission rate among HCBS users with ADRD was 67%, 55%, and 36% for whites, blacks, and others, respectively. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Obstructive sleep apnea (OSA), a prevalent sleep-disordered breathing condition, is increasingly recognized as a modifiable risk factor for cognitive decline and dementia, including Alzheimer’s disease and vascular dementia. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Individuals aged 70 and above experiencing memory loss in Cochran and Parmer Counties had a statistically significant association with cognitive impairment (p < 0.001). 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Social isolation (SI) and loneliness (perceived social isolation) are considered as risk factors for developing dementia, including Alzheimer's disease (AD), in the elderly population. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Full text may need a subscription
29/100
Researchers are focusing on modifiable risk factors for dementia, including sleep disturbances such as insomnia and sleep-disordered breathing (SDB), which are known to increase the risk of dementia, including Alzheimer’s disease (AD) and vascular dementia (VD). 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Acute ischemic stroke often results in a multitude of neuropsychiatric complications, including depression, dementia, delirium, and fatigue. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
From across this tag
10 of the 1,130 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
- Structural and social determinants of dementia risk among adults racialized as Black: Results from a community‐based system dynamics approach
- Life Course Modifiable Risk Factors of Dementia: Replicating the 2024 Lancet Commission Model in a Single Longitudinal Cohort
- Cognitive impairment and dementia: a new emerging complication of type 2 diabetes-The diabetologist's perspective
- Deep multimodal clustering identifies biological subtypes of normal aging with divergent cognitive decline risk
- Relationships between biomarkers in aging and dementia
- Implications of sleep disturbance and inflammation for Alzheimer's disease dementia
- Diabetes and the risk of multi-system aging phenotypes: a systematic review and meta-analysis
- Associations of Regional Brain Structural Differences With Aging, Modifiable Risk Factors for Dementia, and Cognitive Performance
- Oral glycotoxins are a modifiable cause of dementia and the metabolic syndrome in mice and humans
- Contribution of alcohol use disorders to the burden of dementia in France 2008-13: a nationwide retrospective cohort study
Where “Free full text” comes from
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
How the 0–100 score works — and why some entries are capped
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
- Journal tier up to 10 pts
- Journal's citation record up to 4 pts
- Study design up to 12 pts
- Strength of evidence up to 5 pts
- Peer-review validation up to 10 pts
- How recent up to 5 pts
- Sample size up to 4 pts
- Effect reported up to 3 pts
- Studied in people up to 3 pts
- Randomised / blinded up to 2 pts
- Times cited up to 7 pts
- Citations per year up to 5 pts
- Impact for its field and year up to 6 pts
- Cited by studies here up to 6 pts
- Still being cited up to 4 pts
- Senior author's track record up to 4 pts
- Institution's track record up to 3 pts
- Multi-centre collaboration up to 3 pts
- Indexed in PubMed up to 2 pts
- Free to read up to 2 pts
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 27,380 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
What this library is — and isn't
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,380 records, built mostly from automated pulls of Europe PMC (60.6% of the library) and OpenAlex (18.6%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,032 records (3.8% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →